Genomic Location: :...
NR annotation: NXD16146.1, FRDA protein [Nothocercus nigrocapillus]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q05B87 | Frataxin, mitochondrial OS=Bos taurus OX=9913 GN=FXN PE=2 SV=1 | ||||
| O35943 | Frataxin, mitochondrial OS=Mus musculus OX=10090 GN=Fxn PE=1 SV=1 | ||||
| Q16595 | Frataxin, mitochondrial OS=Homo sapiens OX=9606 GN=FXN PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | THAP |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF05153 | MIOX | Myo-inositol oxygenase | Family | Interproscan |
| PF00909 | Ammonium_transp | Ammonium Transporter Family | Family | Interproscan |
| PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF05485 | THAP | THAP domain | Domain | Interproscan |
| PF21788 | TNP-like_GBD | TNP-like, GTP-binding insertion domain | Domain | Interproscan |
| PF21787 | TNP-like_RNaseH_N | TNP-like, RNase H N-terminal domain | Domain | Interproscan |
| PF01491 | Frataxin_Cyay | Frataxin-like domain | Domain | Interproscan |
| PF00786 | PBD | P21-Rho-binding domain | Domain | Interproscan |
| PF00568 | WH1 | WH1 domain | Domain | Interproscan |
| PF02205 | WH2 | WH2 motif | Family | Interproscan |
| PF00004 | AAA | ATPase family associated with various cellular activities (AAA) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR007828 | Family | Inositol oxygenase | Interproscan |
| IPR029020 | Homologous_superfamily | Ammonium/urea transporter | Interproscan |
| IPR024041 | Domain | Ammonium transporter AmtB-like domain | Interproscan |
| IPR036383 | Homologous_superfamily | Thrombospondin type-1 (TSP1) repeat superfamily | Interproscan |
| IPR000884 | Repeat | Thrombospondin type-1 (TSP1) repeat | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR000477 | Domain | Reverse transcriptase domain | Interproscan |
| IPR052035 | Family | Zinc finger BED domain-containing | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR038441 | Homologous_superfamily | THAP-type zinc finger superfamily | Interproscan |
| IPR006612 | Domain | THAP-type zinc finger | Interproscan |
| IPR048366 | Domain | Transposable element P transposase-like, GTP-binding insertion domain | Interproscan |
| IPR052224 | Family | THAP domain-containing protein | Interproscan |
| IPR048365 | Domain | Transposable element P transposase-like, RNase H domain, N-terminal | Interproscan |
| IPR020895 | Conserved_site | Frataxin conserved site | Interproscan |
| IPR002908 | Family | Frataxin/CyaY | Interproscan |
| IPR036524 | Homologous_superfamily | Frataxin/CyaY superfamily | Interproscan |
| IPR017789 | Family | Frataxin | Interproscan |
| IPR000095 | Domain | CRIB domain | Interproscan |
| IPR000697 | Domain | WH1/EVH1 domain | Interproscan |
| IPR029061 | Homologous_superfamily | Thiamin diphosphate-binding fold | Interproscan |
| IPR011026 | Homologous_superfamily | Actin nucleation-promoting factor WAS, C-terminal | Interproscan |
| IPR003124 | Domain | WH2 domain | Interproscan |
| IPR036936 | Homologous_superfamily | CRIB domain superfamily | Interproscan |
| IPR051412 | Family | Formin Homology Diaphanous subfamily | Interproscan |
| IPR033927 | Domain | WASP family, EVH1 domain | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR036691 | Homologous_superfamily | Endonuclease/exonuclease/phosphatase superfamily | Interproscan |
| IPR050168 | Family | AAA ATPase domain-containing protein | Interproscan |
| IPR047533 | Domain | Peroxisomal biogenesis factor 6, second ATPase domain | Interproscan |
| IPR003960 | Conserved_site | ATPase, AAA-type, conserved site | Interproscan |
| IPR003959 | Domain | ATPase, AAA-type, core | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR003593 | Domain | AAA+ ATPase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12588 | MYOINOSITOL OXYGENASE | Interproscan |
| PTHR11730 | AMMONIUM TRANSPORTER | Interproscan |
| PTHR33395 | TRANSCRIPTASE, PUTATIVE-RELATED-RELATED | Interproscan |
| PTHR47027 | REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR46481 | ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 | Interproscan |
| PTHR46927 | AGAP005574-PA | Interproscan |
| PTHR16821 | FRATAXIN | Interproscan |
| PTHR45691 | PROTEIN DIAPHANOUS | Interproscan |
| PTHR33244 | INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED | Interproscan |
| PTHR23077 | AAA-FAMILY ATPASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005506 | Molecular Function | iron ion binding | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0019310 | Biological Process | inositol catabolic process | Interproscan |
| GO:0050113 | Molecular Function | inositol oxygenase activity | Interproscan |
| GO:0008519 | Molecular Function | ammonium channel activity | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0072488 | Biological Process | ammonium transmembrane transport | Interproscan |
| GO:0005887 | Cellular Component | plasma membrane | Interproscan |
| GO:0097272 | Biological Process | ammonium homeostasis | Interproscan |
| GO:0008199 | Molecular Function | ferric iron binding | Interproscan |
| GO:0016226 | Biological Process | iron-sulfur cluster assembly | Interproscan |
| GO:0004322 | Molecular Function | ferroxidase activity | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0006879 | Biological Process | intracellular iron ion homeostasis | Interproscan |
| GO:0018283 | Biological Process | iron incorporation into metallo-sulfur cluster | Interproscan |
| GO:0008198 | Molecular Function | ferrous iron binding | Interproscan |
| GO:0034986 | Molecular Function | iron chaperone activity | Interproscan |
| GO:0051537 | Molecular Function | 2 iron, 2 sulfur cluster binding | Interproscan |
| GO:0007015 | Biological Process | actin filament organization | Interproscan |
| GO:0003779 | Molecular Function | actin binding | Interproscan |
| GO:0005884 | Cellular Component | actin filament | Interproscan |
| GO:0030041 | Biological Process | actin filament polymerization | Interproscan |
| GO:0005778 | Cellular Component | peroxisomal membrane | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0016558 | Biological Process | protein import into peroxisome matrix | Interproscan |
| GO:0016887 | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K23209 | THAP9; DNA transposase THAP9 | EC:2.7.7.- | Mitochondrial biogenesis | ko03029 | deepkoala |
| Membrane trafficking | ko04131 | deepkoala | |||
| Chromosome and associated proteins | ko03036 | deepkoala |