Gene detail

Detailed information of g784.t1 in Calvadosia cruxmelitensis

Genomic Location: not available for this species
NR annotation: XP_047125874.1, MAP kinase-activated protein kinase 2 [Hydra vulgaris]
Species Calvadosia cruxmelitensis · all data for this species · gene families

Sequence

Sequence data are not available for Calvadosia cruxmelitensis.
Nucleotide and protein sequences are provided for the species whose genome annotation is complete (see annotated genomes); for this species only the assembly is archived. The functional annotation below is likewise unavailable.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q3SYZ2	MAP kinase-activated protein kinase 3 OS=Bos taurus OX=9913 GN=MAPKAPK3 PE=2 SV=1
P49137	MAP kinase-activated protein kinase 2 OS=Homo sapiens OX=9606 GN=MAPKAPK2 PE=1 SV=1
P49139	MAP kinase-activated protein kinase 2 (Fragment) OS=Oryctolagus cuniculus OX=9986 GN=MAPKAPK2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000056 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000139 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000154 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000221 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000402 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0001159 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0001649 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0001879 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0003408 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0003958 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0006503 (this species only) · gene tree & orthology
Transcription factor family	bHLH · all TF in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01866 all species →	Diphthamide_syn	Putative diphthamide synthesis protein	Family	Interproscan
PF02826 all species →	2-Hacid_dh_C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	Domain	Interproscan
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF07707 all species →	BACK	BTB And C-terminal Kelch	Domain	Interproscan
PF01344 all species →	Kelch_1	Kelch motif	Repeat	Interproscan
PF00010 all species →	HLH	Helix-loop-helix DNA-binding domain	Domain	Interproscan
PF01663 all species →	Phosphodiest	Type I phosphodiesterase / nucleotide pyrophosphatase	Family	Interproscan
PF12796 all species →	Ank_2	Ankyrin repeats (3 copies)	Repeat	Interproscan
PF16095 all species →	COR	C-terminal of Roc, COR, domain	Family	Interproscan
PF08477 all species →	Roc	Ras of Complex, Roc, domain of DAPkinase	Domain	Interproscan
PF13855 all species →	LRR_8	Leucine rich repeat	Repeat	Interproscan
PF00994 all species →	MoCF_biosynth	Probable molybdopterin binding domain	Domain	Interproscan
PF03453 all species →	MoeA_N	MoeA N-terminal region (domain I and II)	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR016435 all species →	Family	Diphthamide synthesis DPH1/DPH2	Interproscan
IPR042265 all species →	Homologous_superfamily	Diphthamide synthesis DPH1/DPH2, domain 3	Interproscan
IPR042263 all species →	Homologous_superfamily	Diphthamide synthesis DPH1/DPH2, domain 1	Interproscan
IPR006140 all species →	Domain	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain	Interproscan
IPR036291 all species →	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan
IPR035914 all species →	Homologous_superfamily	Spermadhesin, CUB domain superfamily	Interproscan
IPR000358 all species →	Family	Ribonucleotide reductase small subunit family	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR027442 all species →	Homologous_superfamily	MAP kinase activated protein kinase, C-terminal	Interproscan
IPR050205 all species →	Family	Calcium-dependent Serine/Threonine Protein Kinases	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR011705 all species →	Domain	BTB/Kelch-associated	Interproscan
IPR006652 all species →	Repeat	Kelch repeat type 1	Interproscan
IPR015915 all species →	Homologous_superfamily	Kelch-type beta propeller	Interproscan
IPR036638 all species →	Homologous_superfamily	Helix-loop-helix DNA-binding domain superfamily	Interproscan
IPR050283 all species →	Family	E-box Binding Transcriptional Regulators	Interproscan
IPR011598 all species →	Domain	Myc-type, basic helix-loop-helix (bHLH) domain	Interproscan
IPR017850 all species →	Homologous_superfamily	Alkaline-phosphatase-like, core domain superfamily	Interproscan
IPR002591 all species →	Family	Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase	Interproscan
IPR035014 all species →	Domain	cGMP-dependent protein kinase, catalytic domain	Interproscan
IPR032675 all species →	Homologous_superfamily	Leucine-rich repeat domain superfamily	Interproscan
IPR001611 all species →	Repeat	Leucine-rich repeat	Interproscan
IPR036770 all species →	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	Interproscan
IPR002110 all species →	Repeat	Ankyrin repeat	Interproscan
IPR020859 all species →	Domain	Roc domain	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR001453 all species →	Domain	MoaB/Mog domain	Interproscan
IPR032171 all species →	Domain	C-terminal of Roc (COR) domain	Interproscan
IPR036135 all species →	Homologous_superfamily	MoeA, N-terminal and linker domain superfamily	Interproscan
IPR038987 all species →	Family	Molybdopterin biosynthesis protein MoeA-like	Interproscan
IPR036425 all species →	Homologous_superfamily	MoaB/Mog-like domain superfamily	Interproscan
IPR036388 all species →	Homologous_superfamily	Winged helix-like DNA-binding domain superfamily	Interproscan
IPR008284 all species →	Conserved_site	Molybdenum cofactor biosynthesis, conserved site	Interproscan
IPR011044 all species →	Homologous_superfamily	Quinoprotein amine dehydrogenase, beta chain-like	Interproscan
IPR003591 all species →	Repeat	Leucine-rich repeat, typical subtype	Interproscan
IPR005110 all species →	Domain	MoeA, N-terminal and linker domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10762 all species →	DIPHTHAMIDE BIOSYNTHESIS PROTEIN	Interproscan
PTHR43333 all species →	2-HACID_DH_C DOMAIN-CONTAINING PROTEIN	Interproscan
PTHR23409 all species →	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN	Interproscan
PTHR24349 all species →	SERINE/THREONINE-PROTEIN KINASE	Interproscan
PTHR45632 all species →	LD33804P	Interproscan
PTHR23349 all species →	BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST	Interproscan
PTHR10151 all species →	ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE	Interproscan
PTHR24353 all species →	CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE	Interproscan
PTHR10192 all species →	MOLYBDOPTERIN BIOSYNTHESIS PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0017183 all species →	Biological Process	protein histidyl modification to diphthamide	Interproscan
GO:0090560 all species →	Molecular Function	2-(3-amino-3-carboxypropyl)histidine synthase activity	Interproscan
GO:0051287 all species →	Molecular Function	NAD binding	Interproscan
GO:0004748 all species →	Molecular Function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0009263 all species →	Biological Process	deoxyribonucleotide biosynthetic process	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004683 all species →	Molecular Function	calcium/calmodulin-dependent protein kinase activity	Interproscan
GO:0005516 all species →	Molecular Function	calmodulin binding	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0009931 all species →	Molecular Function	calcium-dependent protein serine/threonine kinase activity	Interproscan
GO:0018105 all species →	Biological Process	peptidyl-serine phosphorylation	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0046777 all species →	Biological Process	protein autophosphorylation	Interproscan
GO:0051019 all species →	Molecular Function	mitogen-activated protein kinase binding	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0046983 all species →	Molecular Function	protein dimerization activity	Interproscan
GO:0000977 all species →	Molecular Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Interproscan
GO:0000981 all species →	Molecular Function	DNA-binding transcription factor activity, RNA polymerase II-specific	Interproscan
GO:0006357 all species →	Biological Process	regulation of transcription by RNA polymerase II	Interproscan
GO:0032502 all species →	Biological Process	developmental process	Interproscan
GO:0004692 all species →	Molecular Function	cGMP-dependent protein kinase activity	Interproscan
GO:0032324 all species →	Biological Process	molybdopterin cofactor biosynthetic process	Interproscan
GO:0006777 all species →	Biological Process	Mo-molybdopterin cofactor biosynthetic process	Interproscan
GO:0018315 all species →	Biological Process	molybdenum incorporation into molybdenum-molybdopterin complex	Interproscan
GO:0061599 all species →	Molecular Function	molybdopterin molybdotransferase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04345	PKA; protein kinase A	EC:2.7.11.11	Chromosome and associated proteins	ko03036	deepkoala
K04443	MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2	EC:2.7.11.1	Protein kinases	ko01001	deepkoala
K09073	PTF1A; pancreas-specific transcription factor 1a	-	Transcription factors	ko03000	deepkoala
K10448	KLHL10; kelch-like protein 10	-	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Calvadosia cruxmelitensis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Calvadosia cruxmelitensis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	sequence table not available	–
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	sequence table not available	–
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →