Genomic Location: :...
NR annotation: XP_047125874.1, MAP kinase-activated protein kinase 2 [Hydra vulgaris]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q3SYZ2 | MAP kinase-activated protein kinase 3 OS=Bos taurus OX=9913 GN=MAPKAPK3 PE=2 SV=1 | ||||
| P49137 | MAP kinase-activated protein kinase 2 OS=Homo sapiens OX=9606 GN=MAPKAPK2 PE=1 SV=1 | ||||
| P49139 | MAP kinase-activated protein kinase 2 (Fragment) OS=Oryctolagus cuniculus OX=9986 GN=MAPKAPK2 PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | bHLH |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01866 | Diphthamide_syn | Putative diphthamide synthesis protein | Family | Interproscan |
| PF02826 | 2-Hacid_dh_C | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain | Domain | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF07707 | BACK | BTB And C-terminal Kelch | Domain | Interproscan |
| PF01344 | Kelch_1 | Kelch motif | Repeat | Interproscan |
| PF00010 | HLH | Helix-loop-helix DNA-binding domain | Domain | Interproscan |
| PF01663 | Phosphodiest | Type I phosphodiesterase / nucleotide pyrophosphatase | Family | Interproscan |
| PF12796 | Ank_2 | Ankyrin repeats (3 copies) | Repeat | Interproscan |
| PF16095 | COR | C-terminal of Roc, COR, domain | Family | Interproscan |
| PF08477 | Roc | Ras of Complex, Roc, domain of DAPkinase | Domain | Interproscan |
| PF13855 | LRR_8 | Leucine rich repeat | Repeat | Interproscan |
| PF00994 | MoCF_biosynth | Probable molybdopterin binding domain | Domain | Interproscan |
| PF03453 | MoeA_N | MoeA N-terminal region (domain I and II) | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR016435 | Family | Diphthamide synthesis DPH1/DPH2 | Interproscan |
| IPR042265 | Homologous_superfamily | Diphthamide synthesis DPH1/DPH2, domain 3 | Interproscan |
| IPR042263 | Homologous_superfamily | Diphthamide synthesis DPH1/DPH2, domain 1 | Interproscan |
| IPR006140 | Domain | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain | Interproscan |
| IPR036291 | Homologous_superfamily | NAD(P)-binding domain superfamily | Interproscan |
| IPR035914 | Homologous_superfamily | Spermadhesin, CUB domain superfamily | Interproscan |
| IPR000358 | Family | Ribonucleotide reductase small subunit family | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR027442 | Homologous_superfamily | MAP kinase activated protein kinase, C-terminal | Interproscan |
| IPR050205 | Family | Calcium-dependent Serine/Threonine Protein Kinases | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR011705 | Domain | BTB/Kelch-associated | Interproscan |
| IPR006652 | Repeat | Kelch repeat type 1 | Interproscan |
| IPR015915 | Homologous_superfamily | Kelch-type beta propeller | Interproscan |
| IPR036638 | Homologous_superfamily | Helix-loop-helix DNA-binding domain superfamily | Interproscan |
| IPR050283 | Family | E-box Binding Transcriptional Regulators | Interproscan |
| IPR011598 | Domain | Myc-type, basic helix-loop-helix (bHLH) domain | Interproscan |
| IPR017850 | Homologous_superfamily | Alkaline-phosphatase-like, core domain superfamily | Interproscan |
| IPR002591 | Family | Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase | Interproscan |
| IPR035014 | Domain | cGMP-dependent protein kinase, catalytic domain | Interproscan |
| IPR032675 | Homologous_superfamily | Leucine-rich repeat domain superfamily | Interproscan |
| IPR001611 | Repeat | Leucine-rich repeat | Interproscan |
| IPR036770 | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR002110 | Repeat | Ankyrin repeat | Interproscan |
| IPR020859 | Domain | Roc domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR001453 | Domain | MoaB/Mog domain | Interproscan |
| IPR032171 | Domain | C-terminal of Roc (COR) domain | Interproscan |
| IPR036135 | Homologous_superfamily | MoeA, N-terminal and linker domain superfamily | Interproscan |
| IPR038987 | Family | Molybdopterin biosynthesis protein MoeA-like | Interproscan |
| IPR036425 | Homologous_superfamily | MoaB/Mog-like domain superfamily | Interproscan |
| IPR036388 | Homologous_superfamily | Winged helix-like DNA-binding domain superfamily | Interproscan |
| IPR008284 | Conserved_site | Molybdenum cofactor biosynthesis, conserved site | Interproscan |
| IPR011044 | Homologous_superfamily | Quinoprotein amine dehydrogenase, beta chain-like | Interproscan |
| IPR003591 | Repeat | Leucine-rich repeat, typical subtype | Interproscan |
| IPR005110 | Domain | MoeA, N-terminal and linker domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10762 | DIPHTHAMIDE BIOSYNTHESIS PROTEIN | Interproscan |
| PTHR43333 | 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR23409 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN | Interproscan |
| PTHR24349 | SERINE/THREONINE-PROTEIN KINASE | Interproscan |
| PTHR45632 | LD33804P | Interproscan |
| PTHR23349 | BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST | Interproscan |
| PTHR10151 | ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE | Interproscan |
| PTHR24353 | CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE | Interproscan |
| PTHR10192 | MOLYBDOPTERIN BIOSYNTHESIS PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0017183 | Biological Process | protein histidyl modification to diphthamide | Interproscan |
| GO:0090560 | Molecular Function | 2-(3-amino-3-carboxypropyl)histidine synthase activity | Interproscan |
| GO:0051287 | Molecular Function | NAD binding | Interproscan |
| GO:0004748 | Molecular Function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0009263 | Biological Process | deoxyribonucleotide biosynthetic process | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0004683 | Molecular Function | calcium/calmodulin-dependent protein kinase activity | Interproscan |
| GO:0005516 | Molecular Function | calmodulin binding | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0009931 | Molecular Function | calcium-dependent protein serine/threonine kinase activity | Interproscan |
| GO:0018105 | Biological Process | peptidyl-serine phosphorylation | Interproscan |
| GO:0035556 | Biological Process | intracellular signal transduction | Interproscan |
| GO:0046777 | Biological Process | protein autophosphorylation | Interproscan |
| GO:0051019 | Molecular Function | mitogen-activated protein kinase binding | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0046983 | Molecular Function | protein dimerization activity | Interproscan |
| GO:0000977 | Molecular Function | RNA polymerase II transcription regulatory region sequence-specific DNA binding | Interproscan |
| GO:0000981 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0032502 | Biological Process | developmental process | Interproscan |
| GO:0004692 | Molecular Function | cGMP-dependent protein kinase activity | Interproscan |
| GO:0032324 | Biological Process | molybdopterin cofactor biosynthetic process | Interproscan |
| GO:0006777 | Biological Process | Mo-molybdopterin cofactor biosynthetic process | Interproscan |
| GO:0018315 | Biological Process | molybdenum incorporation into molybdenum-molybdopterin complex | Interproscan |
| GO:0061599 | Molecular Function | molybdopterin molybdotransferase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K04345 | PKA; protein kinase A | EC:2.7.11.11 | Protein kinases | ko01001 | deepkoala |
| Transcription factors | ko03000 | deepkoala | |||
| Ubiquitin system | ko04121 | deepkoala | |||
| Chromosome and associated proteins | ko03036 | deepkoala |