Gene detail

Detailed information of g7888.t1 in Montipora capitata

Genomic Location: Sc0000186:263326...285367
NR annotation: XP_029194535.2, rho-associated protein kinase 2-like isoform X2 [Acropora millepora]
Species Montipora capitata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

g7888.t1

atgcttcttgataaacatggtcacctcaagcttgctgattttgggacatgtatgagaatggacaaggatggtatggtgagatccgacactgccgtggggacacctgattacatctccccagaggttttgaaatcccagggaggtgaaggctactatggccgagagtgtgattggtggagtgtaggtgtcttcctgtatgaattgcttataggtgacacaccattttatgcagactcacttgtaggaacttatgctgttcccccagtagtgcctgaattgttaagtgatgatgatgccacccattttgatgacattcctgagccagacagtggggaggagttttttcccataccaaagacttttgctggcaatcatcttcccttcataggatttacttactctgagactgtaaggtggaataatattcaaaacaagggctctgatggaatggatggaagtcgcagcaatgaaagtggaccaaagctggaggctgcgaaccacaaaatcaaagaattagaagagcaagttagtttggaaatgcaagctagagatgaagtggaacacaattacagaaatgtcagttccaaactagagaaagtaatgaaggaactggacagcgagttggaaaataaaagagcgattgagtcagcaaaccgagaacttgagagaaaggcagcactctttaaacatgatttaaaagaggcccagagacgaggcgaatttgaaaatgaagccaaaaggaagcttgaaggcaaagttcaagaacttcagagccgtcttgatgcagaattggatgctcgagataaaatctcgcagacttcacacagcgtgcagaacaaaatcagccaacttgagaagcaggtctgggatcttacggaccagctgaaaaaggagacagatgcacatgccaaagtgaataagtcgcatggcgaattgcaaaagttatatgctgtaatggaaaggtcacacggggatcttcaagacaagaacagggtcattagtgaacagaaggcaaaagccaatactgaatatgagctcaagtcaatgaagagcaaatttgaaaaggtcactagtgattaccagcaacaaattaccagttttcaaacagagaagaataggctatcattgaccttggaggagagaactgaacaggagcgtgcagaacaaaccaagactttggaaagactggaacaagagctggaatttcgaggaaaagctgaagcagcagccgcagaggctgaaagacagcggcaagtcctagctgtggatcttaaagatatgaatcaaaagtatgagagactgctgcaggaacacaatgctcttcttgacgagaataaagctttgaataccaggctcgactgcgacaaccaaaagaaaacaaatctagaaagtgaattggaactcaatgctcaagaaattctcggtcttagagcaacagaaaagcagctgacaaagcaaatagaggaactgatggatgaacggaaacggttggaggatgcatgtgcaaaactaaaaaatgcgagtgctgtggatgacttgcagatgaaagaacttcaagatcagcttgaggcagaaacgtacttttcgactttatacaaaacacaagtcaaagagttacaagaagaggtcgttgagaaagccaaacagttacaggatttgaattctgagatcaaccagcttaacgaagaacgggaatctctatcagcgcagctggagttaacattaacgaaggctcactcggaacagctcgccaggtcaattgctgaagagcagtattcagacttggaaaaggaaaagaccatgattgagttggaggtcaaagaattgattgccaggcacaagagcgacatgtccgaaaaaggcgcacagataagccagttagaggagctaaatcaacagctaacggactctttgggtcagaaaatggcggagaaagatgagataaattctaaaatcaagggtttgcaagaggaactcgagaaagcaaaggacaatcgcaatgaaattgatactgtcacggaacaattcaaaaagcagcttgaaatcgagaaatcaaaaacaatccaagctgtgaataaactggctgagataatgaacaggaaggactttcagcgtgagaccagcaagaaacgaaaagcaccatctgatgacttgagaaggaaggagaaagaaaataggaaactccatcaggaactaggggcggaagtacagaaaagagtcaaagtacacaatgtgccaccaaacggaacggaactgtgcatggataattatgacaatttcggatacagcaacaattatgtatgcgacgacgacgaagatgatgatgatgttgagtgtgaccaggacgatggtaggttcatttga

Transcript

g7888.t1

ATGCTTCTTGATAAACATGGTCACCTCAAGCTTGCTGATTTTGGGACATGTATGAGAATGGACAAGgaTGGTATGGTGAGATCCGACACTGCCGTGGGGACACCTGATTACATCTCCCCAGAGGTTTTGAAATCCCAGGGAGGTGAAGGCTACTATGGCCGAGAGTGTGATTGGTGGAGTGTAGGTGTCTTCCTGTATGAATTGCTTATAGGTGACACACCATTTTATGCAGACTCACTTGTAGGAACTTATGCTGTTCCCCCAGTAGTGCCTGAATTGTTAAGTGATGATGATGCCACCCATTTTGATGACATTCCTGAGCCAGACAGTGGGGAGGAGTTTTTTCCCATACCAAAGacTTTTGCTGGCAATCATCTTCCCTTCATAGGATTTACTTACTCTGAGACTGTAAGGTGGAATAATATTCAAAACAAGGGCTCTGATGGAATGGATGGAAGTCGCAGCAATGAAAGTGGACCAAAGCTGGAGGCTGCGAACcacaaaatcaaagaattagAAGAGCAAGTTAGTTTGGAAATGCAAGCTAGAGATGAAGTGGAACACAATTACAGaaaTGTCAGTTCCAAACTAGAGAAAGTAATGAAGGAACTGGACAGCGAGTTGGAAAATAAAAGAGCGATTGAGTCAGCAAACCGAGAACTTGAGAGAAAGGCAGCACTCTTTAAACATGATTTAAAAGAGGCCCAGAGACGAGGcgaatttgaaaatgaagcCAAAAGGAAGCTTGAAGGCAAAGTTCAAGAACTTCAGAGCCGTCTTGATGCAGAATTGGATGCTCGAGATAAAATCTCGCAGACTTCACACAGCGTGCAGAACAAAATCAGCCAACTTGAGAAGCAGGTCTGGGATCTTACGGACCAGCTGAAAAAGGAGACAGATGCACATGCCAAAGTGAATAAGTCGCATGGCGAATTGCAAAAGTTATATGCTGTAATGGAAAGGTCACACGGGGATCTTCAAGACAAGAACAGGGTCATTAGTGAACAGAAGGCAAAAGCCAATACTGAATATGAGCTCAAGTCAATGAAGAGCAAATTTGAAAAGGTCACTAGTGATTACCAGCAACAAATTACCAGTTTTCAAACAGAGAAGAATAGGCTATCATTGACCTTGGAGGAGAGAACTGAACAGGAGCGTGCAGAACAAACCAAGACTTTGGAAAGACTGGAACAAGAGCTGGAATTTCGAGGAAAAGCTGAAGCAGCAGCCGCAGAGGCTGAAAGACAGCGGCAAGTCCTAGCTGTGGATCTTAAAGATATGAATCAAAAGTATGAGAGACTGCTGCAGGAACACAATGCTCTTCTTGACGAGAATAAAGCTTTGAATACCAGGCTCGACTGCGACaaccaaaagaaaacaaatctaGAAAGTGAATTGGAACTCAATGCTCAAGAAATTCTCGGTCTTAGAGCAACAGAAAAGCAGCTGACAAAGcAAATAGAGGAACTGATGGATGAACGGAAACGGTTGGAGGATGCATGTGCAAAACTAAAAAATGCGAGTGCTGTGGATGACTTGCAGATGAAAGAACTTCAAGATCAGCTTGAGGCAGAAACGTACTTTTCGACTTTATACAAAACACAAGTCAAAGAGTTACAAGAAGAGGTCGTTGAGAAAGCCAAACAGTTACAGGATTTGAATTCTGAGATCAACCAGCTTAACGAAGAACGGGAATCTCTATCAGCGCAGCTGGAGTTAACATTAACGAAGGCTCACTCGGAACAGCTCGCCAGGTCAATTGCTGAAGAGCAGTATTCAGACTTGGAAAAGGAAAAGACCATGATTGAGTTGGAGGTCAAAGAATTGATTGCCAGGCACAAGAGCGACATGTCCGAAAAAGGCGCACAGATAAGCCAGTTAGAGGAGCTAAATCAACAGCTAACGGACTCTTTGGGTCAGAAAATGGCGGAGAAAGATGAGATAAATTCTAAAATCAAGGGTTTGCAAGAGGAACTCGAGAAAGCAAAGGACAATCGCAATGAAATTGATACTGTCACGGAACAATTCAAAAAGCAGCTTGAAATCGAGAAATCAAAAACAATCCAAGCTGTGAATAAACTGGCTGAGATAATGAACAGGAAGGACTTTCAGCGTGAGACCAGCAAGAAACGAAAAGCACCATCTGATGACTTGAGAAGGAAGGAGAAAGAAAATAGGAAACTCCATCAGGAACTAGGGGCGGAAGTACAGAAAAGAGTCAAAGTACACAATGTGCCACCAAACGGAACGGAACTGTGCATGGATAATTATGACAATTTCGGATACAGCAACAATTATGTATGCGACGACgacgaagatgatgatgatgttgagtGTGACCAGGACGATGGTAGGTTCATTTGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O75116	Rho-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=ROCK2 PE=1 SV=4
Q62868	Rho-associated protein kinase 2 OS=Rattus norvegicus OX=10116 GN=Rock2 PE=1 SV=2
Q28021	Rho-associated protein kinase 2 OS=Bos taurus OX=9913 GN=ROCK2 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002895 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF08912 all species →	Rho_Binding	Rho Binding	Coiled-coil	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR050839 all species →	Family	Rho-associated Serine/Threonine Kinase	Interproscan
IPR015008 all species →	Domain	ROCK, Rho binding domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22988 all species →	MYOTONIC DYSTROPHY S/T KINASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0000281 all species →	Biological Process	mitotic cytokinesis	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005856 all species →	Cellular Component	cytoskeleton	Interproscan
GO:0007266 all species →	Biological Process	Rho protein signal transduction	Interproscan
GO:0018107 all species →	Biological Process	peptidyl-threonine phosphorylation	Interproscan
GO:0030866 all species →	Biological Process	cortical actin cytoskeleton organization	Interproscan
GO:0031032 all species →	Biological Process	actomyosin structure organization	Interproscan
GO:0048598 all species →	Biological Process	embryonic morphogenesis	Interproscan
GO:0072518 all species →	Molecular Function	Rho-dependent protein serine/threonine kinase activity	Interproscan
GO:1901888 all species →	Biological Process	regulation of cell junction assembly	Interproscan
GO:0031267 all species →	Molecular Function	small GTPase binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K17388	ROCK2; Rho-associated protein kinase 2	EC:2.7.11.1	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g7888.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

48TPM > 0

3Conditions

108.4Max TPM

29.7Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organisms · ambient pH treatment	21	21	32.07	108.39
whole organisms · low pH treatment	15	15	24.08	83.21
whole organisms · extra low pH treatment pH treatment	12	12	32.56	103.30

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11452230	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	108.39
SRR11452222	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	104.46
SRR11452228	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	87.24
SRR11452232	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	78.72
SRR11452234	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	53.78
SRR11452231	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	38.16
SRR11452263	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	28.84
SRR11452233	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	26.33
SRR11452251	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	25.23
SRR11452250	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	16.46
SRR11452217	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	12.99
SRR11452262	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	12.46
SRR11452242	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	11.83
SRR11452252	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	11.51
SRR11452246	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	10.58
SRR11452240	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	10.11
SRR11452243	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	9.32
SRR11452259	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	7.49
SRR11452260	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	7.13
SRR11452254	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	6.34
SRR11452237	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	6.08
SRR11452221	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	83.21
SRR11452223	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	79.53
SRR11452224	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	76.67
SRR11452247	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	15.09
SRR11452241	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	14.11
SRR11452249	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	14.04
SRR11452218	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	13.61
SRR11452229	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	12.72
SRR11452216	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	12.55
SRR11452245	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	11.14
SRR11452238	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	9.53
SRR11452236	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	7.56
SRR11452258	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	4.26
SRR11452255	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	3.76
SRR11452253	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	3.40
SRR11452225	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	103.30
SRR11452227	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	98.03
SRR11452226	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	89.62
SRR11452219	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	17.92
SRR11452220	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	14.91
SRR11452244	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	14.71
SRR11452248	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	14.23
SRR11452261	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	11.45
SRR11452239	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	9.37
SRR11452235	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	9.13
SRR11452256	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	4.38
SRR11452257	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	3.59

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.