Gene detail

Detailed information of g8222.t1 in Montipora capitata

Genomic Location: Sc0000199:80728...106429
NR annotation: XP_044163017.1, poly [ADP-ribose] polymerase 1-like isoform X1 [Acropora millepora]
Species Montipora capitata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

g8222.t1

atggccgatgatcttccattcaaagcagaatacgctaagtcaaatcggtcttcctgtaagtcttgcagggacaacatagcaaaggacagcctgagagtggcaaagatggtccagatccccaactggtttcattttagctgtttctttagaaaacacaaggtgaaagctttcactgacattgctgggtttgattcactcagatgggaggaccaggagaagctgaaagaaaaaactggagggggagggggagggggaggtggtgggaaaaaaggagaaacacctgctgttgtggaaaatgatgtttcagatgacctgttggcggagtacgcaaagtctagccgcagtaaatgcaagaactgcacagagcaaattgataagggtgaacttcgtcttgcaaaagtgcaggaacctgatgcagagtctaatgcacctgcaggggtccctatcccttggtggcaccatgttgactgctttgttaaaagccgcgagtctttgtcagtggatgcagctgtaacagcagaatctttcagtggatttaccaagcttaagaaagaagataaagatttgttgaagagtaagctagggtctgggggaaagaaaaaaggaaaaggtagtaagagaaaagctgtagcagtggatgaaacagatgcaaaaagaaaaaagactgcagaggaagatgagattgagataaagcttaaggaacaaagtcagctgttatggaaagtgagggacgacttgcagaagcattgttccttgccagagctaagagagatgttggaggacaatggaatgagtacccaaggaggcgaaagctctttgctcaacagatgctcagatggcatgacctttggcaggcttcttccttgcgaggaatgtagtgatggtcaactggtatacagaacagaaggttattgctgtactggcaatttaacagcatggaccaaatgtatgtttgttacaagggagcctaaacgagctaaatggaaaatttctgatgatctgaaagaggcttctgactttctgaaaaacttcaaatgcaagaaaagaaaaagggttttcccccaaactacttcttcaactgtagtatcacccaaaggaatcaagttagagggagccacgtcaaaaattgtcacaacccctggaaaacctctttctggaatgacatttgctgttattggaaggctccaacagagcaagggaaaactctctgcagcaattcaagatcttggtggttcagtagttgataaagtcaacacttcagtggactgttgtatcagttctcaagctgaagttgacaagaaaagcaagaaaatgtgcgatgcagagaagtctaatgtgccagttgtcagtgaagattaccttgaggctgttaaaaagggcggggccagattaatgatcatgcagcatagcattgtctcttggggaaagaaggatgccagtgtagtggatggtgggcctgtggttgttcccgtcggcaaaggttcaaaggttacaaaaagtgcattggaaggaggccctgcaaagaaaatgaaagtagctgttaaaggaggtgcagcggtagacccagaatcagaaatggaagacacatgtcatgttctccaagagaatggcaatatttacagcgcaactttgggtttggtggacattgtcagaggcgcaaactcttattacaaacttcagctgctgaaggacgacaaagtgaaatcttattatcttttccgttcttgggggcgagttggaacacacattggaggcaataaattggagagttgtggctcgaaggcgaacgccattcgcagctttttggatttgtatggggagaaaacagggaacagctgggaggacagaaagaattttgttaagcatccaaacaagttctatccactagagatcgactatggacaggataatgaagaactaaaatcatccattgcacccggaagtaaatcagtgctcgctcctgctatccaagagcttatcaagatgatatttgatgtggagtccatgaagaaaacactggttgaatttgaacttatttcagatggtggaagctccagctctctattagatgcttcaaacagattttatacattgcttccccatgactttggcatgaagaagccgccgttgttggacaacttggagcttatcaagactaaagttggcatgttggacaacttgcttgacatcgaggtggcttacagtttgttgaagagtggagaaggggatttggccaaagatcctttggacgtgaattacgaaaaactgcaaacagatttggaggttctcgcaaacgattccgaagaattttctatgatcaacgattatgtgaaaaacacccacgctgaaactcacactcagtacgagttgaatgtcatcgaggttttcaaggtgaatcgccatggtgaagccgatcggtttcaaccttttaaagaacttcacaatcgccgtttgttatggcatggatcacgcactacaaattacgctggcatcttgtctcaggggttgagaatcgcgcctcctgaagccccagtgtcggctaactactgtcgaaccacaccatcggataacattggtctgttgatgctctgtgaagtcgctttgggaaatatgcatgaactgactgacgctagttatgttgtgaaacctccaaaaggaaaacatagtgtcaagggatgtggtcggacaggccctgatcccgatgccgatattacgctaactgatggaacgattgttccaagtggtaaaggaaccaatacaactgttcccacgtcaagtcttctttacaacgagtatccttcaatgctacgttcagttttgttctcgccgtgtagtaacagcaatttttttagacctagttttagtcgaaggtcagaagcagagccattgcatcctgttttctga

Transcript

g8222.t1

ATGGCCGATGATCTTCCATTCAAAGCAGAATACGCTAAGTCAAATCGGTCTTCCTGTAAGTCTTGCAGGGACAACATAGCAAAGGACAGCCTGAGAGTGGCAAAGATGGTCCAGATCCCCAACTGGTTTCATTTTAGCTGTTTCTTTAGAAAACACAAGGTGAAAGCTTTCACTGACATTGCTGGGTTTGATTCACTCAGATGGGAGGACCAGGAGAAGCTGAAAGAAAAAactggagggggagggggagggggaggtggtgggaaaaaaggagaaacaCCTGCTGTTGTGGAAAATGATGTTTCAGATGACCTGTTGGCGGAGTACGCAAAGTCTAGCCGCAGTAAATGCAAGAACTGCACAGAGCAAATTGATAAGGGTGAACTTCGTCTTGCAAAAGTGCAGGAACCTGATGCAGAGTCTAATGCACCTGCAGGGGTCCCTATCCCTTGGTGGCACCATGTTGACTGCTTTGTTAAAAGCCGCGAGTCTTTGTCAGTGGATGCAGCTGTAACAGCAGAATCTTTCAGTGGATTTACCAAGCTTAAGAAAGAAGATAAAGATTTGTTGAAGAGTAAGCTAGGGTCTGggggaaagaaaaaaggaaaaggtaGTAAGAGAAAAGCTGTAGCAGTGGATGAAACagatgcaaaaagaaaaaagactgcAGAGGAAGATGAGATTGAGATAAAGCTTAAGGAACAAAGTCAGCTGTTATGGAAAGTGAGGGACGACTTGCAGAAGCATTGTTCCTTGCCAGAGCTAAGAGAGATGTTGGAGGACAATGGAATGAGTACCCAAGGAGGCGAAAGCTCTTTGCTCAACAGATGCTCAGATGGCATGACCTTTGGCAGGCTTCTTCCTTGCGAGGAATGTAGTGATGGTCAACTGGTATACAGaaCAGAAGGTTATTGCTGTACTGGCAATTTAACAGCATGGACCAAATGTATGTTTGTTACAAGGGAGCCTAAACGAGCTAAATGGAAAATTTCTGATGATCTGAAAGAGGCTTCTGACTTTCTGAAAAACTTCAaatgcaagaaaagaaaaagggtTTTCCCCCAAACTACTTCTTCAACTGTAGTATCACCCAAAGGAATCAAGTTAGAGGGAGCCACGTCAAAAATTGTCACAACCCCTGGAAAACCTCTTTCTGGAATGACATTTGCTGTTATTGGAAGGCTCCAACAGAGCAAGggaaAACTCTCTGCAGCAATTCAAGATCTTGGTGGTTCAGTAGTTGATAAAGTCAACACTTCAGTGGACTGTTGTATCAGTTCTCAAGctGAAGTTGAcaagaaaagcaagaaaatgTGCGATGCAGAGAAGTCTAATGTGCCAGTTGTCAGTGAAGATTACCTTGAGGCTGTTAAAAAGGGCGGGGCCAGATTAATGATCATGCAGCATAGCATTGTCTCTTGGGGAAAGAAGGATGCCAGTGTAGTGGATGGTGGGCCTGTGGTTGTTCCCGTCGGCAAAGGTTCAAAGGTTACAAAAAGTGCATTGGAAGGAGGCcctgcaaagaaaatgaaagtaGCTGTTAAAGGAGGTGCAGCGGTAGACCCAGAATCAGAAATGGAAGACACATGTCATGTTCTCCAAGAGAATGGCAATATTTACAGCGCAACTTTGGGTTTGGTGGACATTGTCAGAGGCGCAAACTCTTATTACAAACTTCAGCTGCTGAAGGACGACAAAGTGAAATCTTATTATCTTTTCCGTTCTTGGGGGCGAGTTGGAACACACATTGGAGGCAATAAATTGGAGAGTTGTGGCTCGAAGGCGAACGCCATTCGCAGCTTTTTGGATTTGTATGGGGAGAAAACAGGGAACAGCTGGGAGGACAGAAAGAATTTTGTTAAGCATCCAAACAAGTTCTATCCACTAGAGATCGACTATGGACAGGATAATGAAGAACTAAAATCATCCATTGCACCCGGAAGTAAATCAGTGCTCGCTCCTGCTATCCAAGAGCTTATCAAGATGATATTTGATGTGGAGTCCATGAAGAAAACACTGGTTGAATTTGAACTTATTTCAGATGGTGGAAGCTCCAGCTCTCTATTAGATGCTTCAAACAGATTTTATACATTGCTTCCCCATGACTTTGGCATGAAGAAGCCGCCGTTGTTGGACAACTTGGAGCTTATCAAGACTAAAGTTGGCATGTTGGACAACTTGCTTGACATCGAGGTGGCTTACAGTTTGTTGAAGAGTGGAGAAGGGGATTTGGCCAAAGATCCTTTGGACGTGAATTACGAAAAACTGCAAACAGATTTGGAGgTTCTCGCAAACGATTCCGAAGAATTTTCTATGATCAACGATTATGTGAAAAACACCCACGCTGAAACTCACACTCAGTACGAGTTGAATGTCATCGAGGTTTTCAAGGTGAATCGCCATGGTGAAGCCGATCGGTTTCAACCTTTTAAAGAACTTCACAATCGCCGTTTGTTATGGCATGGATCACGCACTACAAATTACGCTGGCATCTTGTCTCAGGGGTTGAGAATCGCGCCTCCTGAAGCCCCAGTGTCGGCTAACTACTGTCGAACCACACCATCGGATAACATTGGTCTGTTGATGCTCTGTGAAGTCGCTTTGGGAAATATGCATGAACTGACTGACGCTAGTTATGTTGTGAAACCTCCAAAAGGAAAACATAGTGTCAAGGGATGTGGTCGGACAGGCCCTGATCCCGATGCCGATATTACGCTAACTGATGGAACGATTGTTCCAAGTGGTAAAGGAACCAATACAACTGTTCCCACGTCAAGTCTTCTTTACAACGAGTATCCTTCAATGCTACGTTCAGTTTTGTTCTCGCCGTGTAGTAACAGCAATTTTTTTAGACCTAGTTTTAGTCGAAGGTCAGAAGCAGAGCCATTGCATCCTGTTTTCTGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P26446	Poly [ADP-ribose] polymerase 1 OS=Gallus gallus OX=9031 GN=PARP1 PE=1 SV=2
P27008	Poly [ADP-ribose] polymerase 1 OS=Rattus norvegicus OX=10116 GN=Parp1 PE=1 SV=4
P31669	Poly [ADP-ribose] polymerase 1 (Fragment) OS=Xenopus laevis OX=8355 GN=parp1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001433 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00533 all species →	BRCT	BRCA1 C Terminus (BRCT) domain	Family	Interproscan
PF21728 all species →	PADR1_N	PADR1, N-terminal helical domain	Domain	Interproscan
PF08063 all species →	PADR1_Zn_ribbon	PADR1 domain, zinc ribbon fold	Domain	Interproscan
PF00644 all species →	PARP	Poly(ADP-ribose) polymerase catalytic domain	Family	Interproscan
PF05406 all species →	WGR	WGR domain	Domain	Interproscan
PF02877 all species →	PARP_reg	Poly(ADP-ribose) polymerase, regulatory domain	Domain	Interproscan
PF00645 all species →	zf-PARP	Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001357 all species →	Domain	BRCT domain	Interproscan
IPR036616 all species →	Homologous_superfamily	Poly(ADP-ribose) polymerase, regulatory domain superfamily	Interproscan
IPR036957 all species →	Homologous_superfamily	Zinc finger, PARP-type superfamily	Interproscan
IPR036420 all species →	Homologous_superfamily	BRCT domain superfamily	Interproscan
IPR012317 all species →	Domain	Poly(ADP-ribose) polymerase, catalytic domain	Interproscan
IPR001510 all species →	Domain	Zinc finger, PARP-type	Interproscan
IPR008893 all species →	Domain	WGR domain	Interproscan
IPR008288 all species →	Family	Poly [ADP-ribose] polymerase	Interproscan
IPR003034 all species →	Domain	SAP domain	Interproscan
IPR049296 all species →	Domain	PARP1-like, PADR1 domain, N-terminal helical subdomain	Interproscan
IPR012982 all species →	Domain	PARP1-like, PADR1 domain, zinc ribbon fold	Interproscan
IPR036930 all species →	Homologous_superfamily	WGR domain superfamily	Interproscan
IPR050800 all species →	Family	ADP-ribosyltransferase diphtheria toxin-like	Interproscan
IPR004102 all species →	Domain	Poly(ADP-ribose) polymerase, regulatory domain	Interproscan
IPR038650 all species →	Homologous_superfamily	PADR1, C-terminal domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10459 all species →	DNA LIGASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003950 all species →	Molecular Function	NAD+-protein poly-ADP-ribosyltransferase activity	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0051287 all species →	Molecular Function	NAD binding	Interproscan
GO:0005730 all species →	Cellular Component	nucleolus	Interproscan
GO:0006302 all species →	Biological Process	double-strand break repair	Interproscan
GO:0070212 all species →	Biological Process	protein poly-ADP-ribosylation	Interproscan
GO:1990404 all species →	Molecular Function	NAD+-protein ADP-ribosyltransferase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K24070	PARP1; poly [ADP-ribose] polymerase 1	EC:2.4.2.30	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g8222.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

47TPM > 0

3Conditions

93.9Max TPM

24.3Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organisms · ambient pH treatment	21	20	28.22	93.88
whole organisms · low pH treatment	15	15	22.13	41.28
whole organisms · extra low pH treatment pH treatment	12	12	20.14	37.74

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11452232	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	93.88
SRR11452234	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	63.60
SRR11452233	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	53.69
SRR11452231	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	50.01
SRR11452243	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	41.78
SRR11452250	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	38.09
SRR11452242	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	37.73
SRR11452246	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	37.53
SRR11452230	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	35.86
SRR11452252	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	35.45
SRR11452237	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	33.39
SRR11452228	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	29.47
SRR11452222	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	26.62
SRR11452259	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	3.57
SRR11452254	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	3.39
SRR11452260	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	2.58
SRR11452262	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	1.86
SRR11452263	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	1.63
SRR11452217	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	1.33
SRR11452251	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	1.12
SRR11452240	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	0.00
SRR11452249	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	41.28
SRR11452245	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	40.90
SRR11452238	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	40.43
SRR11452247	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	37.48
SRR11452236	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	36.47
SRR11452241	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	35.47
SRR11452221	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	31.23
SRR11452223	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	27.26
SRR11452224	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	24.62
SRR11452255	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	4.36
SRR11452258	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	4.25
SRR11452218	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	2.80
SRR11452253	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	2.65
SRR11452229	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	1.66
SRR11452216	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	1.11
SRR11452248	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	37.74
SRR11452235	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	35.40
SRR11452239	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	35.39
SRR11452244	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	33.63
SRR11452225	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	29.78
SRR11452227	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	29.24
SRR11452226	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	26.55
SRR11452257	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	3.88
SRR11452256	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	3.59
SRR11452261	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	2.68
SRR11452219	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	2.08
SRR11452220	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	1.73

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.