Genomic Location: :...
NR annotation: CAH1266220.1, MFHAS1 [Branchiostoma lanceolatum]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 OS=Homo sapiens OX=9606 GN=LRRK2 PE=1 SV=2 | ||||
| Q5S006 | Leucine-rich repeat serine/threonine-protein kinase 2 OS=Mus musculus OX=10090 GN=Lrrk2 PE=1 SV=2 | ||||
| Q3UHC2 | Leucine-rich repeat serine/threonine-protein kinase 1 OS=Mus musculus OX=10090 GN=Lrrk1 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | Fork_head |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF18701 | DUF5641 | Family of unknown function (DUF5641) | Domain | Interproscan |
| PF00250 | Forkhead | Forkhead domain | Domain | Interproscan |
| PF00098 | zf-CCHC | Zinc knuckle | Domain | Interproscan |
| PF13855 | LRR_8 | Leucine rich repeat | Repeat | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF08477 | Roc | Ras of Complex, Roc, domain of DAPkinase | Domain | Interproscan |
| PF16095 | COR | C-terminal of Roc, COR, domain | Family | Interproscan |
| PF12842 | DUF3819 | CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819 | Domain | Interproscan |
| PF16417 | CNOT1_TTP_bind | CCR4-NOT transcription complex subunit 1 TTP binding domain | Repeat | Interproscan |
| PF04054 | Not1 | CCR4-Not complex component, Not1 | Repeat | Interproscan |
| PF16415 | CNOT1_CAF1_bind | CCR4-NOT transcription complex subunit 1 CAF1-binding domain | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR040676 | Domain | Domain of unknown function DUF5641 | Interproscan |
| IPR036259 | Homologous_superfamily | MFS transporter superfamily | Interproscan |
| IPR050327 | Family | Proton-linked Monocarboxylate Transporter | Interproscan |
| IPR001766 | Domain | Fork head domain | Interproscan |
| IPR036388 | Homologous_superfamily | Winged helix-like DNA-binding domain superfamily | Interproscan |
| IPR036390 | Homologous_superfamily | Winged helix DNA-binding domain superfamily | Interproscan |
| IPR030456 | Conserved_site | Fork head domain conserved site 2 | Interproscan |
| IPR050211 | Family | Forkhead box domain-containing protein | Interproscan |
| IPR047388 | Domain | Protein fork head-like, forkhead domain | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR001878 | Domain | Zinc finger, CCHC-type | Interproscan |
| IPR043128 | Homologous_superfamily | Reverse transcriptase/Diguanylate cyclase domain | Interproscan |
| IPR036875 | Homologous_superfamily | Zinc finger, CCHC-type superfamily | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR001611 | Repeat | Leucine-rich repeat | Interproscan |
| IPR032675 | Homologous_superfamily | Leucine-rich repeat domain superfamily | Interproscan |
| IPR020859 | Domain | Roc domain | Interproscan |
| IPR036770 | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR015943 | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR003591 | Repeat | Leucine-rich repeat, typical subtype | Interproscan |
| IPR036322 | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR051420 | Family | Ser/Thr Protein Kinases with Diverse Regulatory Roles | Interproscan |
| IPR011989 | Homologous_superfamily | Armadillo-like helical | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR016024 | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR032171 | Domain | C-terminal of Roc (COR) domain | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR039034 | Family | Inositol 3,4-bisphosphate 4-phosphatase | Interproscan |
| IPR038535 | Homologous_superfamily | CCR4-NOT subunit 1, TTP binding domain superfamily | Interproscan |
| IPR024557 | Domain | CCR4-NOT transcription complex subunit 1, domain 4 | Interproscan |
| IPR032193 | Domain | CCR4-NOT transcription complex subunit 1, TTP binding domain | Interproscan |
| IPR040398 | Family | CCR4-NOT transcription complex subunit 1 | Interproscan |
| IPR007196 | Domain | CCR4-Not complex component, Not1, C-terminal | Interproscan |
| IPR032191 | Domain | CCR4-NOT transcription complex subunit 1, CAF1-binding domain | Interproscan |
| IPR009011 | Homologous_superfamily | Mannose-6-phosphate receptor binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22955 | RETROTRANSPOSON | Interproscan |
| PTHR11360 | MONOCARBOXYLATE TRANSPORTER | Interproscan |
| PTHR11829 | FORKHEAD BOX PROTEIN | Interproscan |
| PTHR48005 | LEUCINE RICH REPEAT KINASE 2 | Interproscan |
| PTHR12187 | AGAP000124-PA | Interproscan |
| PTHR13162 | CCR4-NOT TRANSCRIPTION COMPLEX | Interproscan |
| PTHR47331 | PHD-TYPE DOMAIN-CONTAINING PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0016021 | Cellular Component | membrane | Interproscan |
| GO:0003700 | Molecular Function | DNA-binding transcription factor activity | Interproscan |
| GO:0006355 | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0043565 | Molecular Function | sequence-specific DNA binding | Interproscan |
| GO:0000978 | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Interproscan |
| GO:0000981 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0009653 | Biological Process | anatomical structure morphogenesis | Interproscan |
| GO:0030154 | Biological Process | cell differentiation | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0016316 | Molecular Function | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity | Interproscan |
| GO:0000288 | Biological Process | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | Interproscan |
| GO:0000932 | Cellular Component | P-body | Interproscan |
| GO:0017148 | Biological Process | negative regulation of translation | Interproscan |
| GO:0030015 | Cellular Component | CCR4-NOT core complex | Interproscan |
| GO:0060090 | Molecular Function | molecular adaptor activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K08035 | FOXA2, HNF3B; forkhead box protein A2, hepatocyte nuclear factor 3-beta | - | Exosome | ko04147 | deepkoala |
| Messenger RNA biogenesis | ko03019 | deepkoala | |||
| Transcription factors | ko03000 | deepkoala |