Genomic Location: :...
NR annotation: XP_032228501.2, STE20/SPS1-related proline-alanine-rich protein kinase isoform X2 [Nematostella vectensis]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| A0A8I5ZNK2 | Serine/threonine-protein kinase OSR1 OS=Rattus norvegicus OX=10116 GN=Oxsr1 PE=1 SV=1 | ||||
| Q6P9R2 | Serine/threonine-protein kinase OSR1 OS=Mus musculus OX=10090 GN=Oxsr1 PE=1 SV=1 | ||||
| Q5R495 | Serine/threonine-protein kinase OSR1 OS=Pongo abelii OX=9601 GN=OXSR1 PE=2 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Alpha-Helix|CUE |
| Ubiquitin Family | E3|E3 activity RING|RING |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF07647 | SAM_2 | SAM domain (Sterile alpha motif) | Domain | Interproscan |
| PF02845 | CUE | CUE domain | Domain | Interproscan |
| PF13639 | zf-RING_2 | Ring finger domain | Domain | Interproscan |
| PF06456 | Arfaptin | Arfaptin-like domain | Domain | Interproscan |
| PF10545 | MADF_DNA_bdg | Alcohol dehydrogenase transcription factor Myb/SANT-like | Domain | Interproscan |
| PF12202 | OSR1_C | Oxidative-stress-responsive kinase 1 C-terminal domain | Domain | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR028994 | Homologous_superfamily | Integrin alpha, N-terminal | Interproscan |
| IPR013761 | Homologous_superfamily | Sterile alpha motif/pointed domain superfamily | Interproscan |
| IPR001660 | Domain | Sterile alpha motif domain | Interproscan |
| IPR043446 | Family | Neurabin-like family | Interproscan |
| IPR003892 | Domain | Ubiquitin system component CUE | Interproscan |
| IPR001841 | Domain | Zinc finger, RING-type | Interproscan |
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR010504 | Domain | Arfaptin homology (AH) domain | Interproscan |
| IPR027267 | Homologous_superfamily | AH/BAR domain superfamily | Interproscan |
| IPR030798 | Family | Arfaptin family | Interproscan |
| IPR033616 | Family | Bridge-like lipid transfer protein family member 1 | Interproscan |
| IPR006578 | Domain | MADF domain | Interproscan |
| IPR039353 | Family | Transcription factor Adf-1 | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR024678 | Domain | Serine/threonine-protein kinase OSR1/WNK, CCT domain | Interproscan |
| IPR047173 | Family | STE20-related kinase adapter protein alpha/beta-like | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR043128 | Homologous_superfamily | Reverse transcriptase/Diguanylate cyclase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46580 | SENSOR KINASE-RELATED | Interproscan |
| PTHR16154 | NEURABIN | Interproscan |
| PTHR15067 | E3 UBIQUITIN-PROTEIN LIGASE RNF8 | Interproscan |
| PTHR12141 | ARFAPTIN-RELATED | Interproscan |
| PTHR31640 | TRANSMEMBRANE PROTEIN KIAA1109 | Interproscan |
| PTHR12243 | MADF DOMAIN TRANSCRIPTION FACTOR | Interproscan |
| PTHR48014 | SERINE/THREONINE-PROTEIN KINASE FRAY2 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0007015 | Biological Process | actin filament organization | Interproscan |
| GO:0014069 | Cellular Component | postsynaptic density | Interproscan |
| GO:0015629 | Cellular Component | actin cytoskeleton | Interproscan |
| GO:0019722 | Biological Process | calcium-mediated signaling | Interproscan |
| GO:0030425 | Cellular Component | dendrite | Interproscan |
| GO:0031175 | Biological Process | neuron projection development | Interproscan |
| GO:0051015 | Molecular Function | actin filament binding | Interproscan |
| GO:0000151 | Cellular Component | ubiquitin ligase complex | Interproscan |
| GO:0005783 | Cellular Component | endoplasmic reticulum | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0006511 | Biological Process | ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0016567 | Biological Process | protein ubiquitination | Interproscan |
| GO:0030968 | Biological Process | endoplasmic reticulum unfolded protein response | Interproscan |
| GO:0061630 | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| GO:0070936 | Biological Process | protein K48-linked ubiquitination | Interproscan |
| GO:0043130 | Molecular Function | ubiquitin binding | Interproscan |
| GO:0019904 | Molecular Function | protein domain specific binding | Interproscan |
| GO:0005543 | Molecular Function | phospholipid binding | Interproscan |
| GO:0006886 | Biological Process | intracellular protein transport | Interproscan |
| GO:0032588 | Cellular Component | trans-Golgi network membrane | Interproscan |
| GO:0034315 | Biological Process | regulation of Arp2/3 complex-mediated actin nucleation | Interproscan |
| GO:0048488 | Biological Process | synaptic vesicle endocytosis | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0006611 | Biological Process | protein export from nucleus | Interproscan |
| GO:0032147 | Biological Process | activation of protein kinase activity | Interproscan |
| GO:0043539 | Molecular Function | protein serine/threonine kinase activator activity | Interproscan |
| GO:1902554 | Cellular Component | serine/threonine protein kinase complex | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K20314 | ARFIP; arfaptin | - | Protein kinases | ko01001 | deepkoala |
| Ubiquitin system | ko04121 | deepkoala | |||
| Membrane trafficking | ko04131 | deepkoala |