Genomic Location: :...
NR annotation: XP_001629084.1, 116 kDa U5 small nuclear ribonucleoprotein component isoform X2 [Nematostella vectensis]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| O08810 | 116 kDa U5 small nuclear ribonucleoprotein component OS=Mus musculus OX=10090 GN=Eftud2 PE=1 SV=1 | ||||
| Q5F3X4 | 116 kDa U5 small nuclear ribonucleoprotein component OS=Gallus gallus OX=9031 GN=EFTUD2 PE=2 SV=1 | ||||
| Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | TF_bZIP |
| Ubiquitin Family | E3|E3 activity RING|PHD |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF10266 | Strumpellin | Hereditary spastic paraplegia protein strumpellin | Family | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF21040 | CEP104-like_TOG | Centrosomal protein CEP104-like, TOG domain | Repeat | Interproscan |
| PF02219 | MTHFR | Methylenetetrahydrofolate reductase | Domain | Interproscan |
| PF00188 | CAP | Cysteine-rich secretory protein family | Domain | Interproscan |
| PF00294 | PfkB | pfkB family carbohydrate kinase | Domain | Interproscan |
| PF04227 | Indigoidine_A | Indigoidine synthase A like protein | Family | Interproscan |
| PF04511 | DER1 | Der1-like family | Family | Interproscan |
| PF07716 | bZIP_2 | Basic region leucine zipper | Coiled-coil | Interproscan |
| PF00009 | GTP_EFTU | Elongation factor Tu GTP binding domain | Domain | Interproscan |
| PF16004 | EFTUD2 | 116 kDa U5 small nuclear ribonucleoprotein component N-terminus | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR019393 | Family | WASH complex, subunit strumpellin | Interproscan |
| IPR011989 | Homologous_superfamily | Armadillo-like helical | Interproscan |
| IPR001841 | Domain | Zinc finger, RING-type | Interproscan |
| IPR007527 | Domain | Zinc finger, SWIM-type | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR050538 | Family | Mitogen-activated protein kinase kinase kinase | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR004621 | Family | Eukaryotic-type methylenetetrahydrofolate reductase | Interproscan |
| IPR029041 | Homologous_superfamily | FAD-linked oxidoreductase-like | Interproscan |
| IPR003171 | Family | Methylenetetrahydrofolate reductase-like | Interproscan |
| IPR013087 | Domain | Zinc finger C2H2-type | Interproscan |
| IPR001283 | Family | Cysteine-rich secretory protein-related | Interproscan |
| IPR018244 | Conserved_site | Allergen V5/Tpx-1-related, conserved site | Interproscan |
| IPR036444 | Homologous_superfamily | Phospholipase A2 domain superfamily | Interproscan |
| IPR035940 | Homologous_superfamily | CAP superfamily | Interproscan |
| IPR034113 | Domain | Golgi-associated plant pathogenesis-related protein 1, SCP domain | Interproscan |
| IPR014044 | Domain | CAP domain | Interproscan |
| IPR022830 | Homologous_superfamily | Indigoidine synthase A-like | Interproscan |
| IPR029056 | Homologous_superfamily | Ribokinase-like | Interproscan |
| IPR002173 | Conserved_site | Carbohydrate/purine kinase, PfkB, conserved site | Interproscan |
| IPR011611 | Domain | Carbohydrate kinase PfkB | Interproscan |
| IPR007342 | Family | Pseudouridine-5'-phosphate glycosidase | Interproscan |
| IPR035952 | Homologous_superfamily | Rhomboid-like superfamily | Interproscan |
| IPR007599 | Family | Derlin | Interproscan |
| IPR046347 | Homologous_superfamily | Basic-leucine zipper domain superfamily | Interproscan |
| IPR004827 | Domain | Basic-leucine zipper domain | Interproscan |
| IPR031106 | Family | CCAAT/enhancer-binding protein C/EBP | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR000795 | Domain | Translational (tr)-type GTP-binding domain | Interproscan |
| IPR031950 | Domain | 116kDa U5 small nuclear ribonucleoprotein component, N-terminal | Interproscan |
| IPR008116 | Family | Sequence-specific single-strand DNA-binding protein | Interproscan |
| IPR006594 | Conserved_site | LIS1 homology motif | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR15691 | WASH COMPLEX SUBUNIT 5 | Interproscan |
| PTHR47027 | REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR48016 | MAP KINASE KINASE KINASE SSK2-RELATED-RELATED | Interproscan |
| PTHR45754 | METHYLENETETRAHYDROFOLATE REDUCTASE | Interproscan |
| PTHR10334 | CYSTEINE-RICH SECRETORY PROTEIN-RELATED | Interproscan |
| PTHR42909 | ZGC:136858 | Interproscan |
| PTHR44464 | WD REPEAT-CONTAINING PROTEIN 17 | Interproscan |
| PTHR11009 | DER1-LIKE PROTEIN, DERLIN | Interproscan |
| PTHR23334 | CCAAT/ENHANCER BINDING PROTEIN | Interproscan |
| PTHR42908 | TRANSLATION ELONGATION FACTOR-RELATED | Interproscan |
| PTHR12610 | SINGLE STRANDED DNA BINDING PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005768 | Cellular Component | endosome | Interproscan |
| GO:0007032 | Biological Process | endosome organization | Interproscan |
| GO:0030041 | Biological Process | actin filament polymerization | Interproscan |
| GO:0051125 | Biological Process | regulation of actin nucleation | Interproscan |
| GO:0071203 | Cellular Component | WASH complex | Interproscan |
| GO:0140285 | Biological Process | endosome fission | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0004489 | Molecular Function | methylenetetrahydrofolate reductase (NAD(P)H) activity | Interproscan |
| GO:0006555 | Biological Process | methionine metabolic process | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0009086 | Biological Process | methionine biosynthetic process | Interproscan |
| GO:0035999 | Biological Process | tetrahydrofolate interconversion | Interproscan |
| GO:0071949 | Molecular Function | FAD binding | Interproscan |
| GO:0005576 | Cellular Component | extracellular region | Interproscan |
| GO:0004623 | Molecular Function | phospholipase A2 activity | Interproscan |
| GO:0006644 | Biological Process | phospholipid metabolic process | Interproscan |
| GO:0050482 | Biological Process | arachidonate secretion | Interproscan |
| GO:0005615 | Cellular Component | extracellular space | Interproscan |
| GO:0004730 | Molecular Function | pseudouridylate synthase activity | Interproscan |
| GO:0016301 | Molecular Function | kinase activity | Interproscan |
| GO:0000839 | Cellular Component | Hrd1p ubiquitin ligase ERAD-L complex | Interproscan |
| GO:0030176 | Cellular Component | obsolete integral component of endoplasmic reticulum membrane | Interproscan |
| GO:0030433 | Biological Process | obsolete ubiquitin-dependent ERAD pathway | Interproscan |
| GO:0030968 | Biological Process | endoplasmic reticulum unfolded protein response | Interproscan |
| GO:0051787 | Molecular Function | misfolded protein binding | Interproscan |
| GO:1990381 | Molecular Function | ubiquitin-specific protease binding | Interproscan |
| GO:0003700 | Molecular Function | DNA-binding transcription factor activity | Interproscan |
| GO:0006355 | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0000978 | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Interproscan |
| GO:0000981 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | Interproscan |
| GO:0006351 | Biological Process | DNA-templated transcription | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0000398 | Biological Process | mRNA splicing, via spliceosome | Interproscan |
| GO:0003924 | Molecular Function | GTPase activity | Interproscan |
| GO:0030623 | Molecular Function | U5 snRNA binding | Interproscan |
| GO:0046540 | Cellular Component | U4/U6 x U5 tri-snRNP complex | Interproscan |
| GO:0071007 | Cellular Component | U2-type catalytic step 2 spliceosome | Interproscan |
| GO:1990904 | Cellular Component | ribonucleoprotein complex | Interproscan |
| GO:0005525 | Molecular Function | GTP binding | Interproscan |
| GO:0003697 | Molecular Function | single-stranded DNA binding | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0045944 | Biological Process | positive regulation of transcription by RNA polymerase II | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K04416 | MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 | EC:2.7.11.25 | Antifolate resistance | ko01523 | deepkoala |
| Ubiquitin system | ko04121 | deepkoala |