Genomic Location: :...
NR annotation: XP_047139351.1, NAD-dependent protein deacetylase sirtuin-6 [Hydra vulgaris]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| A0A250YGJ5 | NAD-dependent protein deacylase sirtuin-6 OS=Castor canadensis OX=51338 GN=SIRT6 PE=1 SV=1 |
| A0A2K5TU92 | NAD-dependent protein deacylase sirtuin-6 OS=Macaca fascicularis OX=9541 GN=SIRT6 PE=1 SV=2 |
| P59941 | NAD-dependent protein deacylase sirtuin-6 OS=Mus musculus OX=10090 GN=Sirt6 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02146 | SIR2 | Sir2 family | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR029035 | Homologous_superfamily | DHS-like NAD/FAD-binding domain superfamily | Interproscan |
| IPR050134 | Family | NAD-dependent sirtuin protein deacylases | Interproscan |
| IPR026590 | Domain | Sirtuin family, catalytic core domain | Interproscan |
| IPR003000 | Family | Sirtuin family | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11085 | NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0000122 | Biological Process | negative regulation of transcription by RNA polymerase II | Interproscan |
| GO:0003714 | Molecular Function | transcription corepressor activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0046969 | Molecular Function | histone H3K9 deacetylase activity, NAD-dependent | Interproscan |
| GO:0070403 | Molecular Function | NAD+ binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11416 | SIRT6, SIR2L6; NAD-dependent protein deacetylase sirtuin 6 | EC:2.3.1.286 | Chromosome and associated proteins | ko03036 | deepkoala |