Genomic Location: :...
NR annotation: XP_032232203.2, degenerin mec-4 [Nematostella vectensis]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q9NY37 | Bile acid-sensitive ion channel OS=Homo sapiens OX=9606 GN=ASIC5 PE=1 SV=1 |
| O01635 | Degenerin-like protein asic-1 OS=Caenorhabditis elegans OX=6239 GN=asic-1 PE=3 SV=2 |
| Q9WU38 | Epithelial sodium channel subunit beta OS=Mus musculus OX=10090 GN=Scnn1b PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00860 | Xan_ur_permease | Permease family | Family | Interproscan |
| PF01472 | PUA | PUA domain | Family | Interproscan |
| PF00858 | ASC | Amiloride-sensitive sodium channel | Family | Interproscan |
| PF20806 | Integrin_A_Ig_3 | Integrin alpha Ig-like domain 3 | Domain | Interproscan |
| PF00566 | RabGAP-TBC | Rab-GTPase-TBC domain | Family | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF13540 | RCC1_2 | Regulator of chromosome condensation (RCC1) repeat | Repeat | Interproscan |
| PF06179 | Med22 | Surfeit locus protein 5 subunit 22 of Mediator complex | Family | Interproscan |
| PF02931 | Neur_chan_LBD | Neurotransmitter-gated ion-channel ligand binding domain | Family | Interproscan |
| PF17917 | RT_RNaseH | RNase H-like domain found in reverse transcriptase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006042 | Family | Xanthine/uracil permease | Interproscan |
| IPR006043 | Family | Nucleobase cation symporter 2 family | Interproscan |
| IPR002478 | Domain | PUA domain | Interproscan |
| IPR036974 | Homologous_superfamily | PUA domain superfamily | Interproscan |
| IPR015947 | Homologous_superfamily | PUA-like superfamily | Interproscan |
| IPR001873 | Family | Epithelial sodium channel | Interproscan |
| IPR048286 | Domain | Integrin alpha, third immunoglobulin-like domain | Interproscan |
| IPR018184 | Conserved_site | Integrin alpha chain, C-terminal cytoplasmic region, conserved site | Interproscan |
| IPR032695 | Homologous_superfamily | Integrin domain superfamily | Interproscan |
| IPR035969 | Homologous_superfamily | Rab-GAP-TBC domain superfamily | Interproscan |
| IPR045913 | Family | GTPase-activating protein TBC20/Gyp8-like | Interproscan |
| IPR000195 | Domain | Rab-GAP-TBC domain | Interproscan |
| IPR051997 | Family | Serine/threonine-protein kinase NEK | Interproscan |
| IPR000408 | Repeat | Regulator of chromosome condensation, RCC1 | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR009091 | Homologous_superfamily | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR009332 | Family | Mediator of RNA polymerase II transcription subunit 22 | Interproscan |
| IPR006202 | Domain | Neurotransmitter-gated ion-channel ligand-binding domain | Interproscan |
| IPR036734 | Homologous_superfamily | Neurotransmitter-gated ion-channel ligand-binding domain superfamily | Interproscan |
| IPR041373 | Domain | Reverse transcriptase, RNase H-like domain | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR050951 | Family | Retrovirus-related Pol polyprotein | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11119 | XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER | Interproscan |
| PTHR11690 | AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED | Interproscan |
| PTHR23220 | INTEGRIN ALPHA | Interproscan |
| PTHR20913 | TBC1 DOMAIN FAMILY MEMBER 20/GTPASE | Interproscan |
| PTHR44535 | PROTEIN CBG16200 | Interproscan |
| PTHR12434 | MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 | Interproscan |
| PTHR37984 | PROTEIN CBG26694 | Interproscan |
| PTHR46113 | SNAC DOMAIN-CONTAINING PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0022857 | Molecular Function | transmembrane transporter activity | Interproscan |
| GO:0055085 | Biological Process | transmembrane transport | Interproscan |
| GO:0005215 | Molecular Function | transporter activity | Interproscan |
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| GO:0005272 | Molecular Function | sodium channel activity | Interproscan |
| GO:0005887 | Cellular Component | plasma membrane | Interproscan |
| GO:0006814 | Biological Process | sodium ion transport | Interproscan |
| GO:0015280 | Molecular Function | ligand-gated sodium channel activity | Interproscan |
| GO:0035725 | Biological Process | sodium ion transmembrane transport | Interproscan |
| GO:0005178 | Molecular Function | integrin binding | Interproscan |
| GO:0007160 | Biological Process | cell-matrix adhesion | Interproscan |
| GO:0007229 | Biological Process | integrin-mediated signaling pathway | Interproscan |
| GO:0008305 | Cellular Component | integrin complex | Interproscan |
| GO:0009897 | Cellular Component | external side of plasma membrane | Interproscan |
| GO:0033627 | Biological Process | cell adhesion mediated by integrin | Interproscan |
| GO:0098609 | Biological Process | cell-cell adhesion | Interproscan |
| GO:0005096 | Molecular Function | GTPase activator activity | Interproscan |
| GO:0005789 | Cellular Component | endoplasmic reticulum membrane | Interproscan |
| GO:0006888 | Biological Process | endoplasmic reticulum to Golgi vesicle-mediated transport | Interproscan |
| GO:0016192 | Biological Process | vesicle-mediated transport | Interproscan |
| GO:0043547 | Biological Process | positive regulation of GTPase activity | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0003712 | Molecular Function | transcription coregulator activity | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0016592 | Cellular Component | mediator complex | Interproscan |
| GO:0005230 | Molecular Function | extracellular ligand-gated monoatomic ion channel activity | Interproscan |
| GO:0006811 | Biological Process | monoatomic ion transport | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K15139 | MED22; mediator of RNA polymerase II transcription subunit 22 | - | Ion channels | ko04040 | deepkoala |
| Transporters | ko02000 | deepkoala | |||
| Chromosome and associated proteins | ko03036 | deepkoala | |||
| Membrane trafficking | ko04131 | deepkoala | |||
| Transcription machinery | ko03021 | deepkoala |