Detailed information of gene02653.t1 in Actinoscyphia liui

Genomic Location: chr1:40158084...40174606
NR annotation: XP_031572435.1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 [Actinia tenebrosa]
Species Actinoscyphia liui · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q8IZJ3C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CPAMD8 PE=1 SV=2
P01023Alpha-2-macroglobulin OS=Homo sapiens OX=9606 GN=A2M PE=1 SV=3
Q5R4N8Alpha-2-macroglobulin OS=Pongo abelii OX=9601 GN=A2M PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0000509 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01835
all species →
MG2MG2 domainDomainInterproscan
PF17789
all species →
MG4Macroglobulin domain MG4DomainInterproscan
PF07703
all species →
A2M_BRDAlpha-2-macroglobulin bait region domainDomainInterproscan
PF07678
all species →
TED_complementA-macroglobulin TED domainRepeatInterproscan
PF00207
all species →
A2MAlpha-2-macroglobulin familyFamilyInterproscan
PF07677
all species →
A2M_recepA-macroglobulin receptor binding domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR002890
all species →
DomainMacroglobulin domainInterproscan
IPR040839
all species →
DomainMacroglobulin domain MG4Interproscan
IPR050473
all species →
FamilyAlpha-2-macroglobulin/Complement systemInterproscan
IPR013783
all species →
Homologous_superfamilyImmunoglobulin-like foldInterproscan
IPR011625
all species →
DomainAlpha-2-macroglobulin, bait region domainInterproscan
IPR009048
all species →
DomainAlpha-macroglobulin, receptor-bindingInterproscan
IPR036595
all species →
Homologous_superfamilyAlpha-macroglobulin, receptor-binding domain superfamilyInterproscan
IPR011626
all species →
DomainAlpha-macroglobulin-like, TED domainInterproscan
IPR019742
all species →
Conserved_siteAlpha-2-macroglobulin, conserved siteInterproscan
IPR041813
all species →
DomainAlpha-2-macroglobulin, TED domainInterproscan
IPR047565
all species →
Conserved_siteAlpha-macroglobulin-like, thiol-ester bond-forming regionInterproscan
IPR001599
all species →
DomainAlpha-2-macroglobulinInterproscan
IPR014756
all species →
Homologous_superfamilyImmunoglobulin E-setInterproscan
IPR008930
all species →
Homologous_superfamilyTerpenoid cyclases/protein prenyltransferase alpha-alpha toroidInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11412
all species →
MACROGLOBULIN / COMPLEMENTInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004866
all species →
Molecular Functionendopeptidase inhibitor activityInterproscan
GO:0005576
all species →
Cellular Componentextracellular regionInterproscan
GO:0005615
all species →
Cellular Componentextracellular spaceInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for gene02653.t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinoscyphia liui tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinoscyphia liui, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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