Gene detail

Detailed information of gene06236.t1 in Actinoscyphia liui

Genomic Location: chr2:31733416...31744240
NR annotation: XP_020914725.1, uncharacterized protein LOC110252281 [Exaiptasia diaphana]
Species Actinoscyphia liui · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

gene06236.t1

ATGGACTCCAAATTAAGAACATCTCAAGCTAAAACTTCAGAAAAGTTTTTTTTCCTGCTTGGCCTATTGTTGGCGTTGATCAGCGATCGCTTCTTTGTGGAGGGCTCACGATCAGGATGCGATGTTCCTTTAGGGATGGAGGATGGAAGAATTAAAGATTGGCAACTGAAAGCATATTCCTATAGCTCAGGATATGATGCAAGGAATGGTCGATTGAATGGTAAAGGGGCATGGTGTGGTCATAGCCTGCAGAAAGATTGGGGAGAGTATTTTCAAATCCGTTTGGATAGAGTGAGGCATGTGTCTGGTGTTGGCACCCAAGGATTGAATATATCAGGAATAACTGGCCTTTTTCCTCAATCATACTGGGTCACGAGATATGCTATAAAGTACAGTTATGATGGCTTTAAATGGTACTGGTACAAATACAGTGGTTCTTCTATGGAATTCATTGGTAATGTTGATTCTACTTCTGAAAGACGTAATAAATTTCGTGACACTTTTATCACAAATTTCCTAAGAATTTATCCTCTTGATTACAAAACAAGCATGTGTCTACGGGTGGAGGTATATGGCTGTCCTCATGATAAAGCTCTTCTACCTCCTCGCATATCCATGACACCAGACCACAACCCGTCTCCTGGTGCTACTATTACATTAACTTGTATTGCTAACATGCCACATGGATTCGAATCACCACGTTTTTACTGGGTCAAAGACGAGGTGCCTGTTAAACCTGATGTTCAACATCACATCTACTCTTTCCAAAACCAATCGGTTTTAAACATTTTTAAAATCGATCCTGTCAATGAGGGTAACTACCAGTGCATTATCAGAAAGTCAAGTCTGCACGCCTCGTCTGACATTAAAACCGTAAAAGTAAAGCCAGTAATATCGATTGTACCAATGGCCTTGACCAAGGTTGAAGGCGAGTCTGCAAACATTTCCTGTCAAGTGGTCAGCGGTGATATCAGCTCAATGAAACTTGTACTGGTTAAACCAGGACCAGCGCCAACAAAGATCGGTGACAACGAAACAACCTTTAGTAATCTTCGTATCAGTAATGGGAACACAAGACAGATTATCACTCACCAGTGTCTTTTAGTCTTCAACAATTCACTGAAAAATCCAGTGGCAAAAAGTCGAGTAGCGTATTTAACGATCATCAAATCAAATTTTCCAAAATGTCGCCAACAACTTGCAAGCAATGTTTATTGGTCATCAACAGCGGCAGGGCTGACTGACGTCAAGCGTTGTCCTGGAAACGACATTGTTTCAGGCCAGGCTACCAGGCGATGTCTAATAGGACGTGATTCTAAACCAACTTGGAGTCAGCCTAATTTTGGCAACTGCACTTCAAAGGAATTCAAAAATTATCTTTTGCAGGCTGAAGCAATATCGAGCGACTACACACCCTCTTACAACGCAAGCGTATTTCTGGAAGTACTGGACAATGCTACAAAGACAGATCCGAACAAGACGCAAGAATTAAATGGTGGAGATATCGCCGTGACTGTGGAGATTCTAGCAATGTTAGTTCACAGCAGCCAAGCCAACATTTCTAGCAATGAAGACCAACAGAATTTCCTACAAGTCTGTAGTAATATTCTAGAAACTACAAATACACAACACTGGACACAGTATGAAGACCAGAGAGAAAAGGGACTGGGTACCAAGGCCTTGTGGAATCAATTGGTTGTTACTGTCGATAGCTATGGTCTTCAGCTGACCAATCAGATGGCAGACTCTACGTACAGGCTCCTCAATACAACAAACATCGCTATGAGACTAGATAGAGTCAATCAGCATAATAAGGTGAAGAAGGAAGGTTTACAGTTTGATTACAAGGAGTTCGGAAGCTCTTTGTTTTTACCAGCAGAATTGTTTTCCAGTGGCTCAGATCATCAGGTCGTTAGTCTAGTGTACAAGACACTAAACTCTGTAATGAGATTTACAAACGATACCAATACCACACAAGTTTTGTCATCCAATACCACCATGGTCTCTAGTGTTGTACGACCAACACCCACTGGACAACTCAAGGAAAAAGTCAAAATCGTTGTAAAAAACAATAGGGTCGTCGACCCAGTTCCACCACGAACGTGTGTGTTTTGGAGACATGGGATGCCAAGATGGTTGACAGACGGTTGTAGCCTGGTAACTAGTGAATCAGACAAACGCGTGACTACTTGTGAATGCGACCACTTGACGGTGTTTGCAGCCCTCATGGATCCTTATGGAGGACCGATTCCAGAGGAACATCGCAACGCTCTAGAGTTAATCTCCATCATAGGTTGTGCCATCTCGTTGTTTGCTGTCCTGTTGACTATCTTAGTGACGATGGTTTTCTGGAGGACTCTGAAAGCACCACGAACCACCGTGCTAATGAACATATGCGTGGCTATTGCTGTGGTGTGTATTCTTGTGATAGCAGAAGAAACTGCACGGGACTCTAAGGTTGGATGCACTGTCATGGCTGTTTTATTGCATTACTTCCTATTGGCTGTGTTCTGCTGGATGTTGTGTGAAGGAGTGCTACTTTATCTCATGATCGTCAGAGTCATTGGTACAATACCTGAAGCAAAAATGAAGTTGTTCTTCCTCTTTGGATGGGGATTTCCTCTCGTTATCGTCGGCATTTCATTGGCTGCCACTCAAACACAGGGTTATGGTTACTATGGAGATCAGACCGCTTGCTGGCTGGCAGTGGACAATGGGCTCATCTGGGCTTTTGTCGCACCTGCTATTGTCGTTCTTTTGATAAACATGGTAGTTTTTATTCTGGTCATACGTCAAATGATGGGCACGCGTCACGTGCAAAATATGTCACGTGATGAAAAAATACGCAATGGTGTCAAGGCAACCGTGGTCATTCTGCCTCTGCTTGGAATCACGTGGGTGTTTGGTTTGCTGGCCTTCAATTCAGCGACGTTGGCCTTCAAGTACATTTTTGCTATCTTCAACTCTCTGCAAGCACTCGTGATCTTTATCTGCCATTGTGTCCTGAACCCACAGGTCAAGGATGCTTGTAAACGTAAATTCAGTCAGTTCAGCAGTTCTGATTTCACTGGTTTGCCTAAACGCAAAGCTTCGCTTGGTAAAATTCGAAAGAAAGAGCAGCTAACTTGCAAGACTTCGAATTGA

Transcript

gene06236.t1

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q5R7Y0	Adhesion G protein-coupled receptor B2 OS=Pongo abelii OX=9601 GN=ADGRB2 PE=2 SV=2
O60241	Adhesion G protein-coupled receptor B2 OS=Homo sapiens OX=9606 GN=ADGRB2 PE=1 SV=2
Q80T32	Adhesion G-protein coupled receptor D1 OS=Mus musculus OX=10090 GN=Adgrd1 PE=2 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000036 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01825 all species →	GPS	GPCR proteolysis site, GPS, motif	Motif	Interproscan
PF00002 all species →	7tm_2	7 transmembrane receptor (Secretin family)	Family	Interproscan
PF00754 all species →	F5_F8_type_C	F5/8 type C domain	Domain	Interproscan
PF13927 all species →	Ig_3	Immunoglobulin domain	Domain	Interproscan
PF16489 all species →	GAIN	GPCR-Autoproteolysis INducing (GAIN) domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036445 all species →	Homologous_superfamily	GPCR family 2, extracellular hormone receptor domain superfamily	Interproscan
IPR046338 all species →	Homologous_superfamily	GAIN domain superfamily	Interproscan
IPR000421 all species →	Domain	Coagulation factor 5/8 C-terminal domain	Interproscan
IPR013783 all species →	Homologous_superfamily	Immunoglobulin-like fold	Interproscan
IPR000832 all species →	Family	GPCR, family 2, secretin-like	Interproscan
IPR017981 all species →	Domain	GPCR, family 2-like, 7TM	Interproscan
IPR000203 all species →	Conserved_site	GPS motif	Interproscan
IPR003598 all species →	Domain	Immunoglobulin subtype 2	Interproscan
IPR036179 all species →	Homologous_superfamily	Immunoglobulin-like domain superfamily	Interproscan
IPR001879 all species →	Domain	GPCR, family 2, extracellular hormone receptor domain	Interproscan
IPR003599 all species →	Domain	Immunoglobulin subtype	Interproscan
IPR007110 all species →	Domain	Immunoglobulin-like domain	Interproscan
IPR008077 all species →	Family	GPCR, family 2, brain-specific angiogenesis inhibitor	Interproscan
IPR032471 all species →	Domain	GAIN domain, N-terminal	Interproscan
IPR008979 all species →	Homologous_superfamily	Galactose-binding-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12011 all species →	ADHESION G-PROTEIN COUPLED RECEPTOR	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004930 all species →	Molecular Function	G protein-coupled receptor activity	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0007186 all species →	Biological Process	G protein-coupled receptor signaling pathway	Interproscan
GO:0004888 all species →	Molecular Function	transmembrane signaling receptor activity	Interproscan
GO:0007166 all species →	Biological Process	cell surface receptor signaling pathway	Interproscan
GO:0005887 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007189 all species →	Biological Process	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Interproscan
GO:0016525 all species →	Biological Process	negative regulation of angiogenesis	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for gene06236.t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinoscyphia liui tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinoscyphia liui, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →