Gene detail

Detailed information of gene09235.t2 in Actinoscyphia liui

Genomic Location: chr3:630080...664112
NR annotation: XP_020900540.1, mothers against decapentaplegic homolog 4 [Exaiptasia diaphana]
Species Actinoscyphia liui · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

gene09235.t2

ATGGATTTCACTTGTCCAATAGATGGCAAAGACAGCAGTTTTGGTAGCAGCCAAAGTGAACCAGACTTTAGACAGGCTGTTGTACCAACAGCTCATCACTTTCCTGGAGGACAAACCATCCCCCCACCTGTATTAGCACCTCAGGAGTTGTATCCCATACATGGTGCAGTAGAGACAGGAATTATTAATCATGATAACCAAGATTCTTCTGCTGGTGTGCCCACACCTTCAGGATGGAGCAGCCCAACGACTCCTAATTTTTCACAGACATCACAAAGTACCCAGGGTTTCTGGACACAGCAAGAGCCTGCAGTTGAGGATGCTGGTCCTATATCAAAACATCCACCACCAGAACATTGGTGTTCGATAGCATACTTTGAACTTGATCAGCAAGTAGGAGAAATCTTCAAAGTGACATCAAGCTGTCCATCAGTAACAGTTGATGGCTATGTTGATCCATCTGGTGGAAGCAGGTTCTGTCTTGGGCAATTATCCAATGTTCATCGAACTGAAGCCAGTGAAAGAGCACGATTGCATATAGGTAAAGGAGTGCAACTGGATGTACGGGGAGAGGGTGATGTGTGGGTACGCTGTTTGAGTGAACACAGTGTCTTTGTTCAAAGCTATTACCTTGATCGGGAAGCAGGAAGGTGTCCTGGTGATGCTGTGCACAAGATATATCCTAGTGCCTACATAAAAGTGTTTGATTTGCGTCAATGTTACCGACAAATGAAGCAACAAGCACAATCTGCCCAGGCTGCAGCAGCTGCTCAAGCTGCTGCTGTTGTGAGTGGTGTGGGACCAGGAGCCCTACTTCCTCAACTGGGACAAGTTAGTGTTGGTGTAGATGACTTAAGGCGGTTATGTATTCTGAGATTAAGTTTTGTCAAGGGATGGGGTCCAGATTATCCACGTAAAAGTATAAAAGAAACACCATGCTGGATTGAAATTCATCTCCACCGTGCTCTTCAACTACTGGATGAAATTCTCATAGGAATGCCCATGCATGAACCACGCCCTCATGATGCATAACTCATAATAATGTACCATTGAAATGAAACATCATCTCATAGGCATCCATGGGACATGAAAAGTGTTTCCTGCTCTAGAAACGAGAAGGGAGAGATTTGATTTATGGCATGGTAGTGAAAGTTTGAATGATCATCCACATGACAGAGAAAAAGGCGATAGTTTACACTAATTGAAGATTATGATTTTATTAAAAATGGGTTGAAATAAGCTGGATGACGTCATTGAGGTTTAGGGCATATATATGAAAATGTTGACTTTTGATACACTTTGATTTCTACACATTTTGCCCTTCATTACTAGAAAATAAAATTCTCAAACTCATTAATAATTCATGAGGATAAAATAAAGAAAATCACTACCATAAAGGAGGTCTGAAAATGTGATACTAATTAAGAAGTTAAATGACTAATAATTATTTGGCTGCGCCTGGTTTTTTCAACCCACTTCCTCAGTGTTTTAAAATCAGAGGAAGAACAGTTACATGTACTCTTTCTCATGCTTGATATATTACTTCCAATAGCACCAAATAACTTTTCATCAACACTAAAAGCATAGTTATTTTAGCAAATCAGATAAGCTTTTTCTATGTTCATTTAAATTATTAACTCCAAAAAAGGTTCATTTCAATGTAAGTTGCATTCTTTAATTATTTAACATCATTACTATCAACATTTATGTTAATAAAATTTCATTATCGCTCATACATACATGTAATTTGGGAATTGAAGCCAAATACCGATTAAATAAAGTCAGTGTCTAACTGAATCGTGAATGTTTGAGGTCAAAACCAAGGAATAATGAATACTGACATTTGTGTATAATATATATGACATTTGCCTAGAATACATACAGGGTGTCTCAAAAGTTCGTGCCTCCTACTTTATAACCGTACATGTATATCTTATTCAATTTTCGCATCAAAGGAATGATGTTTTCAAAAAAGCCTCTACATTATATTAGATATGAGATGTAAGTCTTATATCAAAGTTCAAAATAATATAACGGCAATTTTTTATTTCCCACCAAAACGTGTGGTGTGCGTACTGTTCCATTTCCTGCCTTTTTGTCGGTTGTCTTTCAGTTTAATAATGTTTCTTTAGTTTAGACTTCTTTTTCAGTGATGCATCCTCTAAATACAGCAAAAATATCATGTTTGAGAGCACAAGCTTCTATACTAAGATCCTCAGGGCTGTCTGTAAAAGAAACTTCAAAATTATTTAAGAAAAGTGAGCATTGGGTGAAAAAGTGGTCAGGTTGAGAAGAGTTCGAAGACAAAGCAAGAACGGGAAGGCCAGCAATCTTGAGCAAAATAGCGAAAAATGTCATCGAAAAAGCCAAGTACAAACGAGGTAACTCCACTCAGTAGATTACTAAAAATCTACAGAATAATGGTTTATCTGGTTCAAGAGCGACAGTATGGCGATATATGAATAAAAAATGTGGAAGCCGTTCGACGACAGAATAAACCACTTTCGACAGAAAAACAACTCACAGATCACCTAAAGTTTGCAAAAGAAAACAAACACCTTACTGCACTAGAGCGGGATGATTTTCTTTTTTCAGACGAATGCCCTAACTACCTATTCCAGCTGCCAAATCTGAAGAATGATGTGGTATGGGGCTCACAAGAAAGCCAAGTTCCCCTAGCTTATCAAGTTAAGCAAAGTTCAAAATGGCTCATTTGGGGTGGGATGACCGGTCGCGGCTTGACAAATTTGCACTTTATTCCACAAGGGCAAACTGTCACAGCCAACTACTATACATTGTATCAACAGAATCCTAGAGAAGGAGGCCAAACCATTACTTAGCCGGAGATCTACAACTGAGAAACCCATAAAGAGAAAGTTGTTCAGCTCAAACAAGAACATGACCTTGGTACAAGATGGAGCACCAGCCCATACAGCAAAGTCTACCCAAAATTGGTGTCATCGAAACTTGCCGAATTTCATAAAAAAAGCTGATTGGCCTGCTAATTCTCCAGATATTAACCCAATCGAGAATCTCTGGAGTATTATGGATGAGATTGCATATTACAGAGATCCGATCCTGAAAACCGTGGTACAGCTAAAGAGGCGGCTCTCCGAAGCTTGGAGAAATATCCCCTTGACGTCACTGCAGGAACTGTCGCATTCGATGCCACAACGTCTATGAAACATTATAAAATATAAAGGAGGCCATGCAGGCAGTAATAGTGTAGAATAACGTACCAAAGCACTTGTCGGCCGTTTGTCGGTCGTTTGTCGACCGACTGTTGGCCATTTGTCGGTCGTTTGTCGGTAGTTTGTCGGCCGTTTGTCGGTAGTTTGTCAGCCGTTTGTCGGTCGTTTGTCGGCCATTTGTCGGCCGACTGTCGGTGCAATAATTGTCGGTGGTTTGTCGACCGACTGTTGGTGAACTGTCGGCGGCTTATCGGCGCCATAACTGGTCAAACGACATTGGATAATAAACTCTAAAACTTTCATAAGTCTGACAGATTGGAAAGTACGTTTTCCATCTGTCCAAAGTAGGGGCACGAACTTTTGAGACATATCTTATTAGACAGGGACCGTGGAGACGGAGGGGCTGGGGCGGCTATAGCCACCCCACTTTTTTCAAATATATAAATGAAAATAAGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P97471	Mothers against decapentaplegic homolog 4 OS=Mus musculus OX=10090 GN=Smad4 PE=1 SV=2
Q13485	Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1
Q9GKQ9	Mothers against decapentaplegic homolog 4 OS=Sus scrofa OX=9823 GN=SMAD4 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006604 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03166 all species →	MH2	MH2 domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR017855 all species →	Homologous_superfamily	SMAD-like domain superfamily	Interproscan
IPR001132 all species →	Domain	SMAD domain, Dwarfin-type	Interproscan
IPR008984 all species →	Homologous_superfamily	SMAD/FHA domain superfamily	Interproscan
IPR013790 all species →	Family	Dwarfin	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13703 all species →	SMAD	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006355 all species →	Biological Process	regulation of DNA-templated transcription	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0000978 all species →	Molecular Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Interproscan
GO:0000981 all species →	Molecular Function	DNA-binding transcription factor activity, RNA polymerase II-specific	Interproscan
GO:0006357 all species →	Biological Process	regulation of transcription by RNA polymerase II	Interproscan
GO:0007179 all species →	Biological Process	transforming growth factor beta receptor signaling pathway	Interproscan
GO:0009653 all species →	Biological Process	anatomical structure morphogenesis	Interproscan
GO:0030154 all species →	Biological Process	cell differentiation	Interproscan
GO:0030509 all species →	Biological Process	BMP signaling pathway	Interproscan
GO:0060395 all species →	Biological Process	SMAD protein signal transduction	Interproscan
GO:0070411 all species →	Molecular Function	I-SMAD binding	Interproscan
GO:0071144 all species →	Cellular Component	heteromeric SMAD protein complex	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04501	SMAD4; mothers against decapentaplegic homolog 4	-	AGE-RAGE signaling pathway in diabetic complications	ko04933	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.