Genomic Location: chr3:54068933...54079239
NR annotation: XP_020906073.1, hypoxanthine-guanine phosphoribosyltransferase [Exaiptasia diaphana]
Species Actinoscyphia liui · all data for this species · gene families
| CDS |
| gene12686.t1 |
| Transcript |
| gene12686.t1 |
| Protein |
| gene12686.t1 |
| UniProt accession | Description |
|---|---|
| Q9W719 | Hypoxanthine-guanine phosphoribosyltransferase OS=Gallus gallus OX=9031 GN=HPRT1 PE=2 SV=1 |
| P47959 | Hypoxanthine-guanine phosphoribosyltransferase OS=Meriones unguiculatus OX=10047 GN=HPRT1 PE=2 SV=2 |
| P00492 | Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003271 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00156 all species → | Pribosyltran | Phosphoribosyl transferase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR029057 all species → | Homologous_superfamily | Phosphoribosyltransferase-like | Interproscan |
| IPR050408 all species → | Family | Hypoxanthine-guanine phosphoribosyltransferase | Interproscan |
| IPR000836 all species → | Domain | Phosphoribosyltransferase domain | Interproscan |
| IPR005904 all species → | Family | Hypoxanthine phosphoribosyl transferase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43340 all species → | HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000287 all species → | Molecular Function | magnesium ion binding | Interproscan |
| GO:0004422 all species → | Molecular Function | hypoxanthine phosphoribosyltransferase activity | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0006178 all species → | Biological Process | guanine salvage | Interproscan |
| GO:0032263 all species → | Biological Process | GMP salvage | Interproscan |
| GO:0032264 all species → | Biological Process | IMP salvage | Interproscan |
| GO:0046100 all species → | Biological Process | hypoxanthine metabolic process | Interproscan |
| GO:0006166 all species → | Biological Process | purine ribonucleoside salvage | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00760 | hprT, hpt, HPRT1; hypoxanthine phosphoribosyltransferase | EC:2.4.2.8 | Drug metabolism - other enzymes | ko00983 | deepkoala |
Genes whose expression across the transcriptome samples of Actinoscyphia liui tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinoscyphia liui, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |