Gene detail

Detailed information of gene14769.t1 in Actinoscyphia liui

Genomic Location: chr4:21193494...21201580
NR annotation: XP_020915481.1, breast cancer anti-estrogen resistance protein 3 [Exaiptasia diaphana]
Species Actinoscyphia liui · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

gene14769.t1

ATGTCAGGAAAGAAGAACAAATTGAGCCGCAGTTTTCCTGCTCGAGTTAAAAACGAATCAAAATCTCGATCCCAACTTCCATTTAAAAGGTTTGCCGACTTTCTAACTTTACGAAGAAAAAAGAAGAAAACCGACGATGGATCCAGCTCCCTCGAAAAACAGGCCTGGTTCCATGGCAAAATCAATGCGGAATACGCCGAGATACACTTGAAAAAAAGTGGCGAATTTCTTGTCCGTGAGGACCCTGCAATGCCTGGGGCCTGGTTCATAGCTGTACGAACTAAAGACGTCTCACTTCATCTTGCAATCAATAAACTAAAATCGTCCAAAGGTACGCGCTTCAAGTATCGAATCGAAGACTCCGACTTTGTGTTCGATAGTATTTCGGAACTGATTCGTTTTTACATCAACGAACGACGGCCGGTTTGTATCCGACCTCCTGCGGTTATAACGATCGCTGTGAGTCGAGAAGCTGCGCTACTTTCCGAGGAAGATTTCCGGGGAAGGTTTGCGACGGCAGGAAGTGCAAGACTGAGCCGTTCTTCGAGAAAATTGGAGAGGAAGTCTAGTGATCCAATGCTGTCGACGAGAGTGCCTTCAAGGCTCTATGAAGAAATCGCGGACTCAACACCAATACCAACACCGGAACAAAAAGACTTGAAAGCCGATCCACCGAGAATGGCCGTCAATGGCAGCGGTACTTTGAAGATCGAGAAAAGAAAAAGGTCTGAGGATCATTCGTTACAAACCTCACCTAGATCTCGATCAATGGACAATGTTCTTGATGACTCGAAGAGCGAATCGAAGGACTGGGCTGAGAATTCACTGAACTCGACGTATGACAGTCCGCGCAACATACCCACGCCCGCATCGCCGCCATTCAAAACTCCTTTCACACAGCAAGAGAAAAAGCGTAAAAACTTAGACCCCAGTCTTTTCGAGAGTGACACAGACTATGCAACACCTTCATCCATCCCAGCATCGACAGACGACGAACAAGTATCACGTGACATGAACTATGACATACCGCGTACTAATGTATCTGAAGGCTCAAAGACCTTACTGAACGACAAGAGTGATAGTAAAACTTGTGTGAATCAAAGCAAACGCCAGGAATCCCAGGACAATGAACCCAAAGTCATGGCACAAGATGATAGGCACAACCTTTATCTTACAGTCGTGAACAAGTTGCGTCACGCTGTCGTACAACCGTTTCTGCAACATGACTGTGTCACGTTGGCTCGTCACCTTACTAAAGTTGATCTTGAGGTTGTGTGGAGGGATTCAGACGGTGAAGACGAAGACGGAGGTGCCAAAGGCTTAGAGAGACTGGTGCTGCCACAAGGACGAGAGAAGCGATGCTCCGTCTTGGAAAGATACCAAAACTTGACCTATTGGGTTGGTGCACTAGTAATAGCCGCTGGGGAGATGGCATCAAGGGCTCAAATGGTATCCAAGCTTATTGAACTGGCAGACATATTGAGTGACAAACAAGGGAACCTTGTATCGTTTATGGCTATCGTCGATGGACTTGCCTTACCACAGGTGAGCCGTCTTCATCACACGTGGTCGTGTCTACATCACCAATTCTCCTCTTCAGCGGTTCTCATCCACAGCACTCTGAAGCCCCTAGCGGGACTTTTATCGTCTGGTGCTCCCAGCCCCTTCCCAGGAGTGTGCCTACCATATATGGTCCCCTTAGCCAGGCTTTTGGAGACGACGAGTGACTCAAGCATTGAAGGTTTAGTAAAAGATGATGACAGCCATGGCTTGGATGTTGTGCTTGCTCATTTGAGTGCTGGTAGAACACTTATTCAACAAATAGAGGCTTATAAAATGGAAGCCGAGAGAAACTTAACGTTTGAAGGTGAAAAGTCGGACTTAATGGAATATTTTCAAGAAGGGATCAACGTAAGCAAAGTGTTAGGTGTGAACTCGAATTCGTCGTCCAGGACGCAGAAGCTCATGACTTTGTTGACGTGGTTATCAGAAAACGTTGAACATGGAAGTATGCAAACGTTGTAA

Transcript

gene14769.t1

CGGTTATCGACTTCGGTGCATTGTTAACTCAGTAAATTTGCCTTTCTTTCATCAAACCACATATTCCTTAGACGGGCATTTACATATTGTACGAATCAAACAGGATAGCAGACAAACGCACGATCGTCGGTACACGAGGCCACGTTTTCGGCAAGGTTTTACTCAAGATAATTCATCGAAGGAAAAGATTGGATTTCTTTAACATTTAGAGAAAAACCGACAATCAAAGTTGCTAGTATTGGATTGCGTTACTCTACTCTATGTCACGCAATGTCAGGAAAGAAGAACAAATTGAGCCGCAGTTTTCCTGCTCGAGTTAAAAACGAATCAAAATCTCGATCCCAACTTCCATTTAAAAGGTTTGCCGACTTTCTAACTTTACGAAGAAAAAAGAAGAAAACCGACGATGGATCCAGCTCCCTCGAAAAACAGGCCTGGTTCCATGGCAAAATCAATGCGGAATACGCCGAGATACACTTGAAAAAAAGTGGCGAATTTCTTGTCCGTGAGGACCCTGCAATGCCTGGGGCCTGGTTCATAGCTGTACGAACTAAAGACGTCTCACTTCATCTTGCAATCAATAAACTAAAATCGTCCAAAGGTACGCGCTTCAAGTATCGAATCGAAGACTCCGACTTTGTGTTCGATAGTATTTCGGAACTGATTCGTTTTTACATCAACGAACGACGGCCGGTTTGTATCCGACCTCCTGCGGTTATAACGATCGCTGTGAGTCGAGAAGCTGCGCTACTTTCCGAGGAAGATTTCCGGGGAAGGTTTGCGACGGCAGGAAGTGCAAGACTGAGCCGTTCTTCGAGAAAATTGGAGAGGAAGTCTAGTGATCCAATGCTGTCGACGAGAGTGCCTTCAAGGCTCTATGAAGAAATCGCGGACTCAACACCAATACCAACACCGGAACAAAAAGACTTGAAAGCCGATCCACCGAGAATGGCCGTCAATGGCAGCGGTACTTTGAAGATCGAGAAAAGAAAAAGGTCTGAGGATCATTCGTTACAAACCTCACCTAGATCTCGATCAATGGACAATGTTCTTGATGACTCGAAGAGCGAATCGAAGGACTGGGCTGAGAATTCACTGAACTCGACGTATGACAGTCCGCGCAACATACCCACGCCCGCATCGCCGCCATTCAAAACTCCTTTCACACAGCAAGAGAAAAAGCGTAAAAACTTAGACCCCAGTCTTTTCGAGAGTGACACAGACTATGCAACACCTTCATCCATCCCAGCATCGACAGACGACGAACAAGTATCACGTGACATGAACTATGACATACCGCGTACTAATGTATCTGAAGGCTCAAAGACCTTACTGAACGACAAGAGTGATAGTAAAACTTGTGTGAATCAAAGCAAACGCCAGGAATCCCAGGACAATGAACCCAAAGTCATGGCACAAGATGATAGGCACAACCTTTATCTTACAGTCGTGAACAAGTTGCGTCACGCTGTCGTACAACCGTTTCTGCAACATGACTGTGTCACGTTGGCTCGTCACCTTACTAAAGTTGATCTTGAGGTTGTGTGGAGGGATTCAGACGGTGAAGACGAAGACGGAGGTGCCAAAGGCTTAGAGAGACTGGTGCTGCCACAAGGACGAGAGAAGCGATGCTCCGTCTTGGAAAGATACCAAAACTTGACCTATTGGGTTGGTGCACTAGTAATAGCCGCTGGGGAGATGGCATCAAGGGCTCAAATGGTATCCAAGCTTATTGAACTGGCAGACATATTGAGTGACAAACAAGGGAACCTTGTATCGTTTATGGCTATCGTCGATGGACTTGCCTTACCACAGGTGAGCCGTCTTCATCACACGTGGTCGTGTCTACATCACCAATTCTCCTCTTCAGCGGTTCTCATCCACAGCACTCTGAAGCCCCTAGCGGGACTTTTATCGTCTGGTGCTCCCAGCCCCTTCCCAGGAGTGTGCCTACCATATATGGTCCCCTTAGCCAGGCTTTTGGAGACGACGAGTGACTCAAGCATTGAAGGTTTAGTAAAAGATGATGACAGCCATGGCTTGGATGTTGTGCTTGCTCATTTGAGTGCTGGTAGAACACTTATTCAACAAATAGAGGCTTATAAAATGGAAGCCGAGAGAAACTTAACGTTTGAAGGTGAAAAGTCGGACTTAATGGAATATTTTCAAGAAGGGATCAACGTAAGCAAAGTGTTAGGTGTGAACTCGAATTCGTCGTCCAGGACGCAGAAGCTCATGACTTTGTTGACGTGGTTATCAGAAAACGTTGAACATGGAAGTATGCAAACGTTGTAATATTTAAAAAGAAACTTTAAAGACTTGAAGGGTTTTTGCTGTAAAAAAAACCTCGCCATGAAAGCGAATATCAATAGCTTCCTCCCAAATTTGTCATTTTATTACCATTCCAAATATGGAAATTCCAAATATGGAAATTCCAAATATGGAAATTCCAAATATGGAAATTCCAAATATGGAAATTCCAAATATGGAATTTAGTTACCTAATATGGATTGAAAGGAGCGACATGTTTTGTAAGATTATTTACACCTTAAACTACTATAGAAACAGAATACCTAAGGTATATTAATATAAATATTGTTTGAAACTAGAAGCCAATGAGTTAGGAGTGTAAATTCCCCATACTGAGTCTATATGAAACTCCATTTTCACAAGTCAGGTTATTTTTAGAATCCGCTGAGCCAATCAGAAGAGTCTGACGGATGGTGTCATGTGTTCGACACTTCCGGTTAACCTGACAGAAAAATGGCAGACGAGAGCGGTAGTAGTAGCGAAGCGAGTAGTACCAGTGACTATGAAGAATATGTCGAGAGTTCACTCAGAAGGGAGTTTTGATCCAAGTGAAGATTCAGAGAAAATGGAAATTTAAATTAGCATAATCTGAAAATAACTTAACTTGAGAATATGGGGTTTCACAGGATAAGGTCCAGTTGCATGCTGCTACCTCTTGGGCTACTGATGATACATTTTAGTTGATCTATAATGCACCTATCAATGTTAAGGTGGCACAAGAGCGTTGGGGGAAGGGAAGGTAGCCGGAGCCTAGGGCGGGTAATTGATAGTCATTGTTGGCCCGTGATTAGGGCTTTTACTCATCTTGCTGTGCTTTGTGGTAAAGTTTGACAAACTTTCTGAAAACGTAAATCCCCACCCTATGTCTCGCCTCGCCCAACACCAAATCCCACCCCTCCCACCGGCTTAACATTGATAAGTGAATAAAGGGATCCATGATAGCTGTCTTTAAGGGTAAAAACTAAATAAAACCACCCCACCCCTCCCACCGGCTTAAC

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9QZS8	SH2 domain-containing protein 3C OS=Mus musculus OX=10090 GN=Sh2d3c PE=1 SV=1
Q8N5H7	SH2 domain-containing protein 3C OS=Homo sapiens OX=9606 GN=SH2D3C PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0008455 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00617 all species →	RasGEF	RasGEF domain	Family	Interproscan
PF00017 all species →	SH2	SH2 domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR051853 all species →	Family	Adapter protein with SH2 and Ras-GEF domains	Interproscan
IPR023578 all species →	Homologous_superfamily	Ras guanine nucleotide exchange factor domain superfamily	Interproscan
IPR000980 all species →	Domain	SH2 domain	Interproscan
IPR001895 all species →	Domain	Ras guanine-nucleotide exchange factors catalytic domain	Interproscan
IPR036860 all species →	Homologous_superfamily	SH2 domain superfamily	Interproscan
IPR036964 all species →	Homologous_superfamily	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR14247 all species →	BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0033138 all species →	Biological Process	positive regulation of peptidyl-serine phosphorylation	Interproscan
GO:0005085 all species →	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0007264 all species →	Biological Process	small GTPase-mediated signal transduction	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K23688	BCAR3, SH2D3B; breast cancer anti-estrogen resistance protein 3	-	Domain-containing proteins not elsewhere classified	ko04990	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.