Genomic Location: chr5:25173310...25202921
NR annotation: XP_020912663.1, structural maintenance of chromosomes protein 3 [Exaiptasia diaphana]
Species Actinoscyphia liui · all data for this species · gene families
| CDS |
| gene18890.t1 |
| Transcript |
| gene18890.t1 |
| Protein |
| gene18890.t1 |
| UniProt accession | Description |
|---|---|
| O93309 | Structural maintenance of chromosomes protein 3 OS=Xenopus laevis OX=8355 GN=smc3 PE=1 SV=2 |
| Q9CW03 | Structural maintenance of chromosomes protein 3 OS=Mus musculus OX=10090 GN=Smc3 PE=1 SV=2 |
| Q9UQE7 | Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003497 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02463 all species → | SMC_N | RecF/RecN/SMC N terminal domain | Domain | Interproscan |
| PF06470 all species → | SMC_hinge | SMC proteins Flexible Hinge Domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR024704 all species → | Family | Structural maintenance of chromosomes protein | Interproscan |
| IPR010935 all species → | Domain | SMCs flexible hinge | Interproscan |
| IPR003395 all species → | Domain | RecF/RecN/SMC, N-terminal | Interproscan |
| IPR041741 all species → | Domain | Structural maintenance of chromosomes 3, ABC domain, eukaryotic | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR036277 all species → | Homologous_superfamily | SMCs flexible hinge superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43977 all species → | STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0016887 all species → | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005694 all species → | Cellular Component | chromosome | Interproscan |
| GO:0051276 all species → | Biological Process | chromosome organization | Interproscan |
| GO:0003690 all species → | Molecular Function | double-stranded DNA binding | Interproscan |
| GO:0007064 all species → | Biological Process | mitotic sister chromatid cohesion | Interproscan |
| GO:0034990 all species → | Cellular Component | mitotic cohesin complex | Interproscan |
| GO:0061775 all species → | Molecular Function | cohesin loader activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06669 | SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) | - | Proteoglycans | ko00535 | deepkoala |
Genes whose expression across the transcriptome samples of Actinoscyphia liui tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinoscyphia liui, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |