Genomic Location: chr5:35675550...35685831
NR annotation: XP_020905586.1, malate dehydrogenase, cytoplasmic [Exaiptasia diaphana]
Species Actinoscyphia liui · all data for this species · gene families
| CDS |
| gene19793.t1 |
| Transcript |
| gene19793.t1 |
| Protein |
| gene19793.t1 |
| UniProt accession | Description |
|---|---|
| Q5ZME2 | Malate dehydrogenase, cytoplasmic OS=Gallus gallus OX=9031 GN=MDH1 PE=2 SV=1 |
| Q3T145 | Malate dehydrogenase, cytoplasmic OS=Bos taurus OX=9913 GN=MDH1 PE=2 SV=3 |
| P14152 | Malate dehydrogenase, cytoplasmic OS=Mus musculus OX=10090 GN=Mdh1 PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004850 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00056 all species → | Ldh_1_N | lactate/malate dehydrogenase, NAD binding domain | Domain | Interproscan |
| PF02866 all species → | Ldh_1_C | lactate/malate dehydrogenase, alpha/beta C-terminal domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011274 all species → | Family | Malate dehydrogenase, NAD-dependent, cytosolic | Interproscan |
| IPR010945 all species → | Family | Malate dehydrogenase, type 2 | Interproscan |
| IPR015955 all species → | Homologous_superfamily | Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal | Interproscan |
| IPR001557 all species → | Family | L-lactate/malate dehydrogenase | Interproscan |
| IPR001236 all species → | Domain | Lactate/malate dehydrogenase, N-terminal | Interproscan |
| IPR001252 all species → | Active_site | Malate dehydrogenase, active site | Interproscan |
| IPR022383 all species → | Domain | Lactate/malate dehydrogenase, C-terminal | Interproscan |
| IPR036291 all species → | Homologous_superfamily | NAD(P)-binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23382 all species → | MALATE DEHYDROGENASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0006108 all species → | Biological Process | malate metabolic process | Interproscan |
| GO:0030060 all species → | Molecular Function | L-malate dehydrogenase (NAD+) activity | Interproscan |
| GO:0016615 all species → | Molecular Function | malate dehydrogenase activity | Interproscan |
| GO:0003824 all species → | Molecular Function | catalytic activity | Interproscan |
| GO:0016616 all species → | Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Interproscan |
| GO:0019752 all species → | Biological Process | carboxylic acid metabolic process | Interproscan |
| GO:0005739 all species → | Cellular Component | mitochondrion | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0006099 all species → | Biological Process | tricarboxylic acid cycle | Interproscan |
| GO:0006107 all species → | Biological Process | oxaloacetate metabolic process | Interproscan |
| GO:0006734 all species → | Biological Process | NADH metabolic process | Interproscan |
| GO:0016491 all species → | Molecular Function | oxidoreductase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00025 | MDH1; malate dehydrogenase | EC:1.1.1.37 | Proximal tubule bicarbonate reclamation | ko04964 | deepkoala |
Genes whose expression across the transcriptome samples of Actinoscyphia liui tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinoscyphia liui, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
