Gene detail

Detailed information of gene22798.t1 in Actinoscyphia liui

Genomic Location: chr6:34401786...34428722
NR annotation: XP_020917832.2, protein patched homolog 1 [Exaiptasia diaphana]
Species Actinoscyphia liui · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

gene22798.t1

ATGGCTAACTCAGAGAACTATGTATGGGCGAGAGAGGTTCTACAGGACATCGATGAGGGTCGTGCAACAGGCAACCGTTTAGCACTGAGGATCCGCGCACGCATTCAGAATGGACTCTTCAAATTGGGATGTACCTCTCAGCGCCATTGTGGAAAAATTGTACTTTTTGGATTTTTAGTAATGGCTATTTTTGCCTTTGGGCTTACGCGAGCGGGGCTAGAAACACGAGCCGAAAAGTTATGGGTTGAAGTTGGAGGCCGTCTTGCTGATGAAATACGTTACACTGAATCTGCACTTGGCAAAGAGTACGGCCTGACCTATGAAATTCTGATACAGACTCCTAATTATAAAGGGACTAATATTTTGACTGTGGACTCCATGTTACTACATTTAAAAGCGCTAAGGAAGGCAGCCAAGGTCAAGGTCAAGGTCGACGGTATCGAAAAACAATGGTCGCTACAAGATTTATGTTATAAGCCCAACCTGCCAGGGTTTGAGGATCGCCTTCTTAAAAACATCATGGAGCAGCTGGTACCATGTACTTTCATTACACCTATGGATTGTTTCTGGGAGGGAGCAAAGATCCATGGTCCAGAAATTGATGTAGCATTACCGGACGATCCGTCAAAGAAATACCTGAAATGGACAAGTCTTAATCCACTTGGATTGTTGAACCTTGTTCAGAAGCAGTTTTACCTTTACCCATGGGAAATGGAGAAAATACGGTTAATGTTTCGAGAGGCTGGAATAACCACAGGCTACTTACAGAAGCCGTGTCTTAACCCCAAAGACCCCGAGTGTCCTTCTTTGGCTCCCAATTTTAACTCCAAGGAGACCCCTGACGTTGGCTCGGTCCTTACTAGCGGTTGCCATGGTTTCGCAGTAAATTACATGAAGTGGCCCGAGGAGATGATAGTCGGTGGAGTCACAAAAAACCGATCTGGTACAATTAGAAGTGCGTCCGCCCTGCAGAGCGTCGTGTTGTTGATGGGTGCTGCTAATCTGCTGGAGTACCACCAAGATAAAGACTGGGCCAAGCAAGACTTGATAACCTGGAACATCACCACGGCAAGAAGGATCTTAGCAGCTTGGCAAAAACAGTTCACCAAGGAAATGAACGAGGTAGCAGATCCAAAGAAAGATGAATTCAGTATTTTAGCTTTTTCTTCAGCATCTTTCGATGAGCTGTTAAAGGACTTCTCTAAGACAAGTACCTTTCGACTTGCAATGGGATATATGCTAATGTTGGTGTATTCGTGCTTGACTCTCAAGCGATGGAATGACGCCGTGCAGTCCCAGGGTGCATTGGGTGTGGCAGGGGTGTTGTTGGTTACAGTATCTGTGGCGTCAGGACTTGGGTTCTGTTCGTTTTGTGGGATTGCACTTAACGCTGCCTCTACCCAGGTTTTGCCGTTTCTTGCTCTGGGGCTTGGAGTAGATGACATGTTTCTGTTGGCACACACCTACGCTGCGATCTCTGAGCGTGGACAAATCCATCCATCGGACCAAGTGGGCTACACCTTGGGCAACACGGGTGTCAGTATATTTCTGACATCCTTTAACAACATGTTCGCTTTTCTTATGGCAGCCATTATCCCTATTCCAGCATTGAGGGCGTTTTCCTTCCAGGCTGCCGTTATCGTGGTGTTCAACTACCTTGCTGTCATCATAGTCTACCCCGCCATGTTGGCTATCGATGTGAAGCGAAAACAGGATCAGCGTTACGACATCTTCTGCTGCTGTCAAAGTGATACACCCCAAAGGATATCTATAACACCCAACTCATCAAGTGATACTGCTATGGTTCTGAGAAGATACCACAACTCAAGTAGTTCGCTGTCTTCTGCGTCGTCCACCGCAATGAACGCCGGGGCCGCCGCAGTACTACCGGGAAGTGTGCAAGCTACAGCCAGTGGAACAGTGTCCCTACCTGGGGCTATTACTCTACGGGCCTCGGCTGTGGCGGAACTGAGTAACCGAACGATGCTACCGTTGTCCGTTAGTGAACTCGTACCTATGGATGAACTCTCAAATCGTGTATATAATGTACCTACAAGTAATGGGAGACCCCGTGCGGGAGGCTGCCATTGCATTGGAATTAGAGACCAGTCTAGTGAGGCGACTTTCTGCACAGATATCGTGCCGAGAGCAACTAACACAGTTCGTCATGACATTATCCCTACACTGGTACCCACGGGACGAAGACATTTACCACGAACTTACAACAAAACGTTAGAGCAAACTCTGCAGCCCAATGTTCGCACGAATGGACGCAGTTCGGCGCATTCTCAATGTGAAGCTCCTAAGCATGTGAATGATATTGAAACCACTACAACTTCAAAATGGACAAGTTTGAAAGAGAAACTGCAGCACTTCTCAATGTCCAACTTTGCAAAGTATTATTATGGACCGTGGCTACAGAAGTCTTCTACTAAGATCTTCGTCCTTTTTACATTCGCCGCCCTGTTTGGTGCCGGCATGTATAGTTGTCTACTTGTCCGTGATGGACTGGACCTAGCAGATGTGGTTCCCAGGAACAGCACGGAGCATCGGTTCGTGACGTCACAGGTCAAGTACTTCTCTATCTACAACATGTATCTTGTTACTATGAAGGACTTTGATTATCCCAACGGACAAAAGCTGCTCTACAAGTACCACGATGCTTTCAAAAGTGTAACCAATGTGGTTAAGACGCCTGAGATGAAGCTTGCACCATTTTGGTTGATGTACTTTAGAAACTGGCTCAAAGACGTTCAAAAGGCGTTTGATGAAGACTGGGCTCTAGGAGCAATAACATACGATGGGTGGAGGCAAAATGCTAGCGATAGTGGCATCATTGGCTATAAGCTACTGGCCCAGACTGGAAATGAAGACACCCCAATTGACAGATCACAAGTTCACTCCGTGCGGCTTGTCGACGATGAAGACATCATCAATCCTAAAGCGTTTTACAACTATTTGACGGCCTGGTATAATTCTGATCCCTTGGGTTTTGAGTCATCTAAGGGTAATATCCGACCCAACCCTGAACTGTGGAATAATAACAGAGACGTTAAGGAGTACCACAATATGAGGATCCAAGCTGCCAAACCCATCGAGTTTGCACAGATTATGTTTTACATTGTCAACCTTAAGGAAACCAGCGATTATGTCAAAATAATAAAGGATGTTCGTGAAATCTGTGACCAGTTCAAAGACAGGGGTCTGCCATCGTACCCTAGTGGAATTCCTTTCATCTTCTGGGAACAATACATTTGGCTGCGACATAATCTTCTCATGGCAATAGCTATTATCCTAGCTATCAGTTTTGTAGTCATGATGGTTGTCTTGTGTAATGTCTGGGCTGCAATGATCATAGTTGCTACCCTCACCGCGATAACAGTCGAAGTGTTTGGCTTCATGGGTGTGGCTGGCATCAAACTAAGTGCAGTTCCTGCTGTTACTCTGATTCTCTCTGTGGGCGTCGGTGTGGAGTTCACTGTCCACATGTGCCTGGCTTTCCAAACTGCACTTGGTGACAAGAACAGCCGTATGCAAAAGGCAGTCGAGCAGGTGTTTTCACCAATCACTGACGGTGCTGTATCAACTCTACTGGGCGTGATAATGCTTGCTGGCTCAGAGTTTGACTTCATTGTAAGATACTTTTTCCATCTCCTGTGCGCGTTGATCATCATTGGTTTTATGAATGGGTTGGTATTCCTTCCTGTTTTGCTCTCATTTATTGGACCGTCACCTGAGGTGGAAGAAATCCGACCACCAGGAACTGCGTCGTCTGCAGGCTCACAGCGTGAACTTCTACCCGTCTCGATATGTCGACGAGGAACTCCGCCAACAGATTCTCAAATTTGCATCCTCGAAACCTCAACCCACGACAGCAGACACGACGATCGAACAGAGAGTAGTCGTCGACATCGGAAAAGACAACGCGATGAAAATAGTTACGGCAATAGGCGTGTTCATGCGACTAACAGTCACAAATCGAGTACACCGACAAGAATGCAATATGAGTTGGAATCGACAAGTTCAGTTGTTGCGAGGGTAACGGCTACTGCTACTGTTACGGTCGAAGTGAAAACTGAGCAGATTCCTATTGAACATTATTGCGATACTGTTCAACCTAACCGAACAGATGGGGGTGTTACGATTGTAGACTTGGACGATCATAGCGTTGTTAAGTAG

Transcript

gene22798.t1

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q61115	Protein patched homolog 1 OS=Mus musculus OX=10090 GN=Ptch1 PE=1 SV=1
Q13635	Protein patched homolog 1 OS=Homo sapiens OX=9606 GN=PTCH1 PE=1 SV=2
Q98864	Protein patched homolog 1 OS=Danio rerio OX=7955 GN=ptch1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002045 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02460 all species →	Patched	Patched family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR003392 all species →	Family	Protein patched/dispatched	Interproscan
IPR000731 all species →	Domain	Sterol-sensing domain	Interproscan
IPR004766 all species →	Family	Transmembrane receptor, patched	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46022 all species →	PROTEIN PATCHED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0008158 all species →	Molecular Function	hedgehog receptor activity	Interproscan
GO:0005119 all species →	Molecular Function	smoothened binding	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0045879 all species →	Biological Process	negative regulation of smoothened signaling pathway	Interproscan
GO:0097108 all species →	Molecular Function	hedgehog family protein binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K06225	PTCH1; patched 1	-	Basal cell carcinoma	ko05217	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.