Gene detail

Detailed information of gene24061.t2 in Actinoscyphia liui

Genomic Location: chr7:6850921...6866769
NR annotation: XP_020896134.1, NPC intracellular cholesterol transporter 1 isoform X3 [Exaiptasia diaphana]
Species abbreviation ALIUI · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

gene24061.t2

ATGGGAATGTTGGGGTTTGTTTTGGTGGCTGTGTTGTTGGGTTTAGTTCAGGCGAAGGATCCTGCCCCTATCCACAAGAAAGGATACTGTGTATGGTACGATGTATGCTATGAACAAGAGGGCAAGGCGCTCAACTGTCTCTACAATGGACCCGCAAAGACACTAAATGACAGTCGAGGAATTGAAGTTCTAAACAAACTTTGTCCGAAATTTGCTGCTGATAGAAAAACATGTTGTTCCACCAAACAGCTTGTGTCTTTGGACAGCAATCTCGACACTTTGAGGCAGTTTGCAAGTCGCTGCCCAGCTTGTTTGCAAAATCTGATCGACTTGTTCTGCGAATCAACCTGTAGCCCCGATCAGTCGCTATTCATGGACCCATCTCAAATATTAAAGTTAACAAACGAATCCATCCTGGAAATAAATTATTATGCTTCTACTCAATTCAAGAAAGGTCTTTTTGATTCGTGCAAGAACGTTGTTTTTCCTGAAGATAACGAGAAAATTCTGAACCTTCTTTGTGGGCGGAGTGCTGAGACATGCACTCCCCAGAAATTACTGGAACACATGGGAAGCACTGCCAATGGTATGTCCCCTTTTAATATAATTTTCCCTCAGATTCGGCCAATGAACCTTACATGGATGGATGAGCCAACCTTCAAGTGCAATGAGAGTTTTGTCAACCAATGGACCAATAAGACAGAACTGAAATGTAGCTGTCAAGATTGTGCCTCTTCTTGTCCCGTCCTCCCACCCTTGCCCAAAGCAGGTGAACACAAGACGATTCTTGGAATGAGAGTGTTATCTTTCTCCTTGCTCATGGTCTACCTTGCATTCTTCTTCACATTTCTTCCTATAAGCTTCTATTTGATCTACAGACGACGACATCAATATGCTCGTATTCCAGATGGGCCAGAACCTGTATCCTCTAATATGCAATACACAAATGAGCAGCCTTCGAAACCTGTCAATGTTGCCCGGAAACCAGGCTGCTTTGAGGTGATGGGTTTCTGGATGGACAAGAAGTTCAGGGACGTCTTCTCCAAGTGGGGTCATTGGTGCAGTCTACATCCTTTCATTGTGATTGGTGCATCAGTGATCTTTGTTGGGATTTTAGCCATAGGACTGAGATATTACAAAGTTACCAAAGATCCTGTAGAACTGTGGTCGGCACCTGAAAGTACAGCAAGAAGAGAGAAAGATCTTTTCGATTCCAAGTTTACTCCATTTTATCGGACAGAACAACTGATCATAACTGCAAACCCAAAGTATCCTCAGAACCACACAGGGTATAAACGGTACCCCGACAGCAAGTTCATCCCATTTGGAAACATGTTCCACCTTGATTTACTGAATCAAGCTTTGGAACTTCAACAAGTACTCACCAACATGTCAGTGCCCTTTGAGGAAGATGGCAAAACTATCAACATTACCCTGGAAGATGTGTGCTTTAAGCCTCTGGCTCCTTACAACAGCAAGTGTGTCATACAGAGTTTATTCCAGTACTTTCAGAATAGCAAAGAAAAGCTGAATCGTTGCATAACCGATATTGAGTCCCACTCATGTTGGAACCACAAAAAAGAAAACTTCCAAGCTGACTTCCACGACCATGTTAGATATTGTACAAGTGCTCCATCTTCACTGACAGACAAGAAATGGGGTGGCGGCCCTTGTCTTGGAGAAAATGGCATTCCCATCAATCCTAACATCATCTTGGGTGGGTTTAATGGTACCGATTACAATATGGCGAATGCCTTGATCATTACCTTTGTTGTTAATAATCACAAAGACGAGAGCCTGAATGCCAAAGCTGAGGCCTGGGAAAAAGCATTTATTGAATTGATGACAGTTTATGTGAAGGATAAGGAACAGAATGGCAATCTGATCATTAGCTACTCATCAGAAAGATCCATCCAAGACGAGCTTGATCGGGAGAGTGAGACAGATGTAGCAACTATACTTGTTAGTTACACCATTATGTTCATTTATATCACTATCGCACTGGGACAAGTTAACTCCTGCAGACGAATAATGATTGATTCCAAGTTCACCTTGGGATTCTGTGGAATTATCATTGTACTATGTTCAGTAATTTGTTCCATTGGTTTCTGGAGTTACATTGGTGAACCAGCCACCCTCATTATCATAGAAGTCGTGCCATTCCTGGTCCTTGCGGTAGGTGTGGACAATTTCTTCATTTTGGTCCAAGCCTACCAGCGCTTTAATCGCTACAGTAACGAGGACATACCTAACAAAGTTGGTCGTGCTCTTGGCGAAGTTGCACCAAGTATGCTTCTATCATCTTTAGCAGAATCAGTTGCCTTTGCTTTTGGTGCCATGTCCAACATGCCTGCCGTCAAAGTATTCTCACTATATGCAGCTGTTGCCGTCTTCATTGATTTCATTTTCCAAATCACATGGTTTGTCGCTTTACTGTCATTGGACGCTAGACGTCAGGAAAGCAATCGAATGGACATCTTGTGCTGTGTGAAGGATAAGGACACCACTGTGAAGTACGAAGAGGGTTTTCTTCACCAGTTCATGGAAAAGATCTATGCTCCTGCTTTGCTGTCAGACTACGTCAGGCCTTGTGTGATTGCTTTCTTTGTGGGAATGTTATTCACTAGCATTTCAATGACTGCACATATATCGGTTGGGTTGGATCAAGAACTAGCATTACCCAAGGATTCCTTCCTTCTTGACTGGTTTAAAGACATGAAAGAATACCTGCATGTTGGTGCCCCTGTGTATTTTGTACTTGATGGTCCTTATGATTATGTAAATCCTAAAACACAAAATAAGATATGTGCTTCGGCAGGATGTGATTCTGATTCTCTTGTCCAGCAAGTCTTCATAGCTTCCCTCCGAAAAAACAGTTCCAAGATTGCCATGCCTGCATCATCCTGGCTTGATGACTACTTTTCTTGGATCGACCCTCGTAGCACATGCTGTCGGGTTCTACTCAATCAGACGACCCATAAACCTGTTATGCCTTTAGTGCTATGTAATGCTACAGATCACGAGCACAAGTGTCAACAATGCATGAACAAAACACAGGCAGGAAAACACCCCACATCTGAAGACTTCTACAAATTCTTACCACTCTATTTACAAGACATCCCAGAAACAACTTGTGCCAAGGGTGGGCATGCTGCCTATGGTCATGCTCTGCAGCTCAACACAAACCCTGGTGCTAAATACCCTGTCAACTCTTCATATTATATGTCCTATCACACAATCCTCAAGACTTCAGATGACTTTGTAGCTGCACTAAAGAGTGCCCATGAAATAGCAGACAGTATAACCAAGGTTATTGACGACCCAAATATCAAGGTCTTCCCTTACAGTGTTTTCTATGTCTTCTATGAACAGTACCTCACCATCGTAAGAGATTCCTGGCACAATCTCTTGTATTGTGCTGCGGCGGTATTTGTTGTGACCTTCCTCTTAATGGGTTTCAACCTGAGTATAGCGGCGATAGTAACGTTCACCGTAGCTATGATAGTAACCAACTTGTTAGGCCTGATGTACTGGTGGAATATAACACTGAATGCCATCTCTCTGGTAAACTTAGTCATGGCGGTTGGTATATCTGTGGAATTCTGTTCTCACATAGCAAGGGCATTTGCTGTTGATTTGCATGACACCAAAATTGAAAGAGCACAGGACGCACTGGCTCACATGGGAAGTTCTGTACTAAGTGGCATCACCCTTACTAAGTTTGGTGGTATTATAGTTTTAGCTTTTGCCAAATCAAGAATATTTGAGATATTTTACTTCAGAATGTACGTTGGGATGGTGCTCTTTGGGGCTCTACATGGCTTAGTTTTCTTACCAGTTTTGCTAAGTTACATTGGACCATGCTCATCTAGACTAAGAGCTCTAGTTGACGATGCAGGAACAGATGCTGAAAAAGCCCCTTTATTAACAAAACAATAA

Transcript

gene24061.t2

GTAAACCTTGGACTTTGCTCAAGGACTCTTCACTGGATTTGTCGAAAAAATTAGCATTTGTGACTTGGAATAAGTCACTGAGAACGGACTTTAAGCGTATTTGGACTTGACAGCGAAAAAAATCTGCCTGAAATGGGAATGTTGGGGTTTGTTTTGGTGGCTGTGTTGTTGGGTTTAGTTCAGGCGAAGGATCCTGCCCCTATCCACAAGAAAGGATACTGTGTATGGTACGATGTATGCTATGAACAAGAGGGCAAGGCGCTCAACTGTCTCTACAATGGACCCGCAAAGACACTAAATGACAGTCGAGGAATTGAAGTTCTAAACAAACTTTGTCCGAAATTTGCTGCTGATAGAAAAACATGTTGTTCCACCAAACAGCTTGTGTCTTTGGACAGCAATCTCGACACTTTGAGGCAGTTTGCAAGTCGCTGCCCAGCTTGTTTGCAAAATCTGATCGACTTGTTCTGCGAATCAACCTGTAGCCCCGATCAGTCGCTATTCATGGACCCATCTCAAATATTAAAGTTAACAAACGAATCCATCCTGGAAATAAATTATTATGCTTCTACTCAATTCAAGAAAGGTCTTTTTGATTCGTGCAAGAACGTTGTTTTTCCTGAAGATAACGAGAAAATTCTGAACCTTCTTTGTGGGCGGAGTGCTGAGACATGCACTCCCCAGAAATTACTGGAACACATGGGAAGCACTGCCAATGGTATGTCCCCTTTTAATATAATTTTCCCTCAGATTCGGCCAATGAACCTTACATGGATGGATGAGCCAACCTTCAAGTGCAATGAGAGTTTTGTCAACCAATGGACCAATAAGACAGAACTGAAATGTAGCTGTCAAGATTGTGCCTCTTCTTGTCCCGTCCTCCCACCCTTGCCCAAAGCAGGTGAACACAAGACGATTCTTGGAATGAGAGTGTTATCTTTCTCCTTGCTCATGGTCTACCTTGCATTCTTCTTCACATTTCTTCCTATAAGCTTCTATTTGATCTACAGACGACGACATCAATATGCTCGTATTCCAGATGGGCCAGAACCTGTATCCTCTAATATGCAATACACAAATGAGCAGCCTTCGAAACCTGTCAATGTTGCCCGGAAACCAGGCTGCTTTGAGGTGATGGGTTTCTGGATGGACAAGAAGTTCAGGGACGTCTTCTCCAAGTGGGGTCATTGGTGCAGTCTACATCCTTTCATTGTGATTGGTGCATCAGTGATCTTTGTTGGGATTTTAGCCATAGGACTGAGATATTACAAAGTTACCAAAGATCCTGTAGAACTGTGGTCGGCACCTGAAAGTACAGCAAGAAGAGAGAAAGATCTTTTCGATTCCAAGTTTACTCCATTTTATCGGACAGAACAACTGATCATAACTGCAAACCCAAAGTATCCTCAGAACCACACAGGGTATAAACGGTACCCCGACAGCAAGTTCATCCCATTTGGAAACATGTTCCACCTTGATTTACTGAATCAAGCTTTGGAACTTCAACAAGTACTCACCAACATGTCAGTGCCCTTTGAGGAAGATGGCAAAACTATCAACATTACCCTGGAAGATGTGTGCTTTAAGCCTCTGGCTCCTTACAACAGCAAGTGTGTCATACAGAGTTTATTCCAGTACTTTCAGAATAGCAAAGAAAAGCTGAATCGTTGCATAACCGATATTGAGTCCCACTCATGTTGGAACCACAAAAAAGAAAACTTCCAAGCTGACTTCCACGACCATGTTAGATATTGTACAAGTGCTCCATCTTCACTGACAGACAAGAAATGGGGTGGCGGCCCTTGTCTTGGAGAAAATGGCATTCCCATCAATCCTAACATCATCTTGGGTGGGTTTAATGGTACCGATTACAATATGGCGAATGCCTTGATCATTACCTTTGTTGTTAATAATCACAAAGACGAGAGCCTGAATGCCAAAGCTGAGGCCTGGGAAAAAGCATTTATTGAATTGATGACAGTTTATGTGAAGGATAAGGAACAGAATGGCAATCTGATCATTAGCTACTCATCAGAAAGATCCATCCAAGACGAGCTTGATCGGGAGAGTGAGACAGATGTAGCAACTATACTTGTTAGTTACACCATTATGTTCATTTATATCACTATCGCACTGGGACAAGTTAACTCCTGCAGACGAATAATGATTGATTCCAAGTTCACCTTGGGATTCTGTGGAATTATCATTGTACTATGTTCAGTAATTTGTTCCATTGGTTTCTGGAGTTACATTGGTGAACCAGCCACCCTCATTATCATAGAAGTCGTGCCATTCCTGGTCCTTGCGGTAGGTGTGGACAATTTCTTCATTTTGGTCCAAGCCTACCAGCGCTTTAATCGCTACAGTAACGAGGACATACCTAACAAAGTTGGTCGTGCTCTTGGCGAAGTTGCACCAAGTATGCTTCTATCATCTTTAGCAGAATCAGTTGCCTTTGCTTTTGGTGCCATGTCCAACATGCCTGCCGTCAAAGTATTCTCACTATATGCAGCTGTTGCCGTCTTCATTGATTTCATTTTCCAAATCACATGGTTTGTCGCTTTACTGTCATTGGACGCTAGACGTCAGGAAAGCAATCGAATGGACATCTTGTGCTGTGTGAAGGATAAGGACACCACTGTGAAGTACGAAGAGGGTTTTCTTCACCAGTTCATGGAAAAGATCTATGCTCCTGCTTTGCTGTCAGACTACGTCAGGCCTTGTGTGATTGCTTTCTTTGTGGGAATGTTATTCACTAGCATTTCAATGACTGCACATATATCGGTTGGGTTGGATCAAGAACTAGCATTACCCAAGGATTCCTTCCTTCTTGACTGGTTTAAAGACATGAAAGAATACCTGCATGTTGGTGCCCCTGTGTATTTTGTACTTGATGGTCCTTATGATTATGTAAATCCTAAAACACAAAATAAGATATGTGCTTCGGCAGGATGTGATTCTGATTCTCTTGTCCAGCAAGTCTTCATAGCTTCCCTCCGAAAAAACAGTTCCAAGATTGCCATGCCTGCATCATCCTGGCTTGATGACTACTTTTCTTGGATCGACCCTCGTAGCACATGCTGTCGGGTTCTACTCAATCAGACGACCCATAAACCTGTTATGCCTTTAGTGCTATGTAATGCTACAGATCACGAGCACAAGTGTCAACAATGCATGAACAAAACACAGGCAGGAAAACACCCCACATCTGAAGACTTCTACAAATTCTTACCACTCTATTTACAAGACATCCCAGAAACAACTTGTGCCAAGGGTGGGCATGCTGCCTATGGTCATGCTCTGCAGCTCAACACAAACCCTGGTGCTAAATACCCTGTCAACTCTTCATATTATATGTCCTATCACACAATCCTCAAGACTTCAGATGACTTTGTAGCTGCACTAAAGAGTGCCCATGAAATAGCAGACAGTATAACCAAGGTTATTGACGACCCAAATATCAAGGTCTTCCCTTACAGTGTTTTCTATGTCTTCTATGAACAGTACCTCACCATCGTAAGAGATTCCTGGCACAATCTCTTGTATTGTGCTGCGGCGGTATTTGTTGTGACCTTCCTCTTAATGGGTTTCAACCTGAGTATAGCGGCGATAGTAACGTTCACCGTAGCTATGATAGTAACCAACTTGTTAGGCCTGATGTACTGGTGGAATATAACACTGAATGCCATCTCTCTGGTAAACTTAGTCATGGCGGTTGGTATATCTGTGGAATTCTGTTCTCACATAGCAAGGGCATTTGCTGTTGATTTGCATGACACCAAAATTGAAAGAGCACAGGACGCACTGGCTCACATGGGAAGTTCTGTACTAAGTGGCATCACCCTTACTAAGTTTGGTGGTATTATAGTTTTAGCTTTTGCCAAATCAAGAATATTTGAGATATTTTACTTCAGAATGTACGTTGGGATGGTGCTCTTTGGGGCTCTACATGGCTTAGTTTTCTTACCAGTTTTGCTAAGTTACATTGGACCATGCTCATCTAGACTAAGAGCTCTAGTTGACGATGCAGGAACAGATGCTGAAAAAGCCCCTTTATTAACAAAACAATAAATTACCATAGGAACAAATTCAGATAGGTGTTCTACTTTCGTATGTACTTGGGCATGGTTGTGTTCGGTGCCCTACATGGGCTTGTCTTTTTACCTGTATTTTTAAGCTATATTGGACCCAGGCCTTCTCGTGATCCAAACATGTCGAAGGAAGAGCCCATGCGGGGTAGCTTCATCAATGGGGAAACCAAGCCACTGTTGGGTTCTAGTTATGCAACTATTCAATAACAGACATTGGAATTAAGTGATATAAAAATCAATAAGCTAGTCCAAATGAAATACAAATTTGAGTGAGTGGCTTATTATTCATCCCCTAATCACTGGGCAGTCAGTACATGTATGTATGTAAAGGGAAGGGAACAATGTAGTTTCCAGTTCCCCTCGTCTCGTGTTACACAGGGTTACCACAATCTCATGCTATGAGTACATGTTGAAGAACTATGTGGAACTTGTAACATACGTACGTCTCCAGATTTATTGATTAATATATGGAATTTTAAATATTGTCAACTAAGGATTACAGCACTACTGAATTTAGTCCTATATATCTATCAAATTACAATAAATGAGGTTTTATATCATG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O15118	NPC intracellular cholesterol transporter 1 OS=Homo sapiens OX=9606 GN=NPC1 PE=1 SV=2
P56941	NPC intracellular cholesterol transporter 1 OS=Sus scrofa OX=9823 GN=NPC1 PE=2 SV=1
O35604	NPC intracellular cholesterol transporter 1 OS=Mus musculus OX=10090 GN=Npc1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001652 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF16414 all species →	NPC1_N	Niemann-Pick C1 N terminus	Domain	Interproscan
PF12349 all species →	Sterol-sensing	Sterol-sensing domain of SREBP cleavage-activation	Family	Interproscan
PF02460 all species →	Patched	Patched family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR032190 all species →	Domain	Niemann-Pick C1, N-terminal	Interproscan
IPR000731 all species →	Domain	Sterol-sensing domain	Interproscan
IPR003392 all species →	Family	Protein patched/dispatched	Interproscan
IPR004765 all species →	Family	NPC1-like	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45727 all species →	NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0015918 all species →	Biological Process	sterol transport	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0032934 all species →	Molecular Function	sterol binding	Interproscan
GO:0005319 all species →	Molecular Function	lipid transporter activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K12385	NPC1; Niemann-Pick C1 protein	-	Transporters	ko02000	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.