Genomic Location: chr7:22218352...22222476
NR annotation: XP_020905061.1, caspase-3 [Exaiptasia diaphana]
Species Actinoscyphia liui · all data for this species · gene families
| CDS |
| gene25142.t2 |
| Transcript |
| gene25142.t2 |
| Protein |
| gene25142.t2 |
| UniProt accession | Description |
|---|---|
| P55866 | Caspase-3 OS=Xenopus laevis OX=8355 GN=casp3 PE=2 SV=1 |
| Q60431 | Caspase-3 OS=Mesocricetus auratus OX=10036 GN=CASP3 PE=2 SV=1 |
| P70677 | Caspase-3 OS=Mus musculus OX=10090 GN=Casp3 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000279 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00656 all species → | Peptidase_C14 | Caspase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011600 all species → | Domain | Peptidase C14, caspase domain | Interproscan |
| IPR029030 all species → | Homologous_superfamily | Caspase-like domain superfamily | Interproscan |
| IPR015917 all species → | Domain | Peptidase C14A, caspase catalytic domain | Interproscan |
| IPR033139 all species → | Active_site | Peptidase family C14A, cysteine active site | Interproscan |
| IPR002138 all species → | Domain | Peptidase C14, caspase non-catalytic subunit p10 | Interproscan |
| IPR016129 all species → | Active_site | Peptidase family C14A, His active site | Interproscan |
| IPR001309 all species → | Domain | Peptidase C14, p20 domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR47901 all species → | CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004197 all species → | Molecular Function | cysteine-type endopeptidase activity | Interproscan |
| GO:0006508 all species → | Biological Process | proteolysis | Interproscan |
| GO:0008234 all species → | Molecular Function | cysteine-type peptidase activity | Interproscan |
| GO:0050727 all species → | Biological Process | regulation of inflammatory response | Interproscan |
| GO:0072557 all species → | Cellular Component | IPAF inflammasome complex | Interproscan |
| GO:0072559 all species → | Cellular Component | NLRP3 inflammasome complex | Interproscan |
| GO:0097169 all species → | Cellular Component | AIM2 inflammasome complex | Interproscan |
gene25142.t2.Genes whose expression across the transcriptome samples of Actinoscyphia liui tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinoscyphia liui, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |