Gene detail

Detailed information of gene27105.t1 in Actinoscyphia liui

Genomic Location: chr8:17893706...17906678
NR annotation: XP_020916930.1, delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [Exaiptasia diaphana]
Species Actinoscyphia liui · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

gene27105.t1

ATGCTTTCTCTACGAACTAAGGTTGCCCAGCATCTCATCAGAGTTGCTGGAGCAAGAACATTGACCATGCCACCTAATGAACCAGCTACTGACTTTGTTGGTGAAAACAGAACCAAACTACTTGAAGCCATCAAAAAGCTTGAAAGTGAAACTCTTGAGGTTCCAGTGATTTCTGGTGGAGAGAAAATTTATACTGGGAACTGTTGTTACCAATCTATTCCATATGATCATGCCAAAAAGATAGCTAAATACCACACTGCAGACGAGGCATTAATTAAGAAAACAATTGAAAGAGCAATGGCAGCCAGAAAGGAATGGGAAAGAACTCCATTTGAAGAAAGGGCAGTTATCTTTGAAAAGGCTTCAGACCTGCTATGTAATAAATACAAATATGACATGCTTGCATCTACCATGGTTGGACAGGGAAAAACGGCCTATGAAGCTGACATTGATTCAGTCATGGAACTCATTGACTTCTATAGATTTGACATCTACAATGGCAGAAAACTCATGAAAGGTCCAGAACTCCATCAACCTCCTGGTGTAAAGAACTCTTTAGTCTACCGTGGATTAGAGGGTTTCGTCGCTGCTGTAGCTCCTTTCAACTTTACAGCCATTGGTGGCAATCTTGCTGCCACGCCTGCAATTATGGGCAATGTAGTCCTCTATAAACCTTCAAGTACAGCTGTTCATTCGTCGTACTTGATAACACAGATCTTTGAGGAGGCTGGACTTCCTGCTGGCATCTTAAATTTTGTGCCCAGTTCTGGACCTGTGTTTGGTAATGGTATCACAACATCTCCAGACTTAGCAGCTATCAACTTTACAGGCAGTGTAAATACATTCAAGACAATATGGCAGAATGTATCCAATAACCTGGATGTTTACAAAACATATCCAAGGCTCATAGGAGAATGTGGCGGCAAGAATTATCATTTTATTCACAACTCTGCTGACGTCAATCGAGTTGTACACTGCACACTGCGAGCAGCATATGGTTACCAGGGACAGAAATGTTCAGCGTGTTCTAGATTGTATGTACCAGAGTCTCTATGGCCTGAGATCAAAGAAGGTTTGCTAGAGGAGCACAAGAAAATACAAATGGGTTCACCTGCAGATCTTGAAAATACCTTTGTTACAGCAGTCATTGACGAAAAGTCCTTTGACAACATTAAGTCATACATTGACTTCTCTAATGACAGCGATGAACTCACAATTTTAGCTGGCGGCAAATGTGACAAGAGTGTGGGATACAACATTCAACCAACGATAGTACAGACAACAAACCCAATGAACAAGATGATGAAAGAAGAAATCTTTGGTCCTATTGTAACTGTGTATGTCTATCCTGATGCCAAGTACAAGGAGACTCTTGAACTGGTTGATCAGACTACTGAGTTTGGACTTACAGGAGCTATATTTGGAGAAGACAAGGATTTCTTAGCAGAAGCCAGCGATATACTGAGGGAGTCCGCTGGTAACTTCTACCTCAATGATAAGTGCACAGGTTCAGTTGTTCAACAGCAACCATTTGGAGGTGCACGAATGTCAGGTACCAATGATAAGGCTGGTGGGCTCATGTACCTTTTAAGGTGGACATCAGCCTTGATTGTCAAGGAGACGTCAGGAGACCCAGGACCCTGGCAGTACCCCCACATGAAGCAATAAATACCACCAACCTATTGCATAGGCCATTATGCACTAAGAGGTCACGTGACCCCATCCCCCTTAAATCAAGCAGCAGTGTCAACTAAAATGAACTCCAGAAATGAATTAAAGAGCAGCTCGATATTAGTAAAAAGGTGAAGTTTCAGCTCATAATATTTGATACAGGAGAAATGACATAAAATATAAAACTGAACGTTTCTAAAAAAAATATTTGGAAATGCATTGGATGGCAACTTTTGCCATCCAGCACATTTTCGTTTGACAATCCTAATAAAATTTTCGATTTTATATTTAAAGCTATTTCTCCTGTGTTAAACATTGTGAGATGAAACTTCGCGTTTTTACTAATATCGAGCTGCTCTTTTCATTTCTGGTGGGCATTTTGACACTGCTGCTTGATTTAAGGGAGGTAGGATCACGTGACCTCTTAGTCCATGTGGCCTTTTGCACTGAGAGTGGATATGGACACCAAAAACATTACCATACACTTATTTTAAAAGACGTTGCCAGTAGAAATGACCTTAAGTTTATGAGAGTAGACCGAGAATGAGTATGGTTTGAAATAATAGAGCTTACCTTGCCTTATACAACTTAAAGACCTTTACTTGCCATATTGTTGAAAATCAAAGTCAAAGCCGAAAATCGAGTGACTATTACATCTACCCATACTCCCTTTCGGTTTAGTCGCGTAGATTTGAGGTTCTGCGACCGCCAACGATTTAGAACTAGGTGTACGCTTAATGGCAAATGTTGTAGCAGTTGTACGCTGAATTGTAGAGTTATATTTTGATAGAATCAGCCAAGCAATGATTATTTAAGATGACTGTGTGCGAATTTTAACCCGTTTTATCAGTCAAAGTCGAC

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A7YWE4	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Bos taurus OX=9913 GN=ALDH4A1 PE=2 SV=1
P30038	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH4A1 PE=1 SV=3
Q8CHT0	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Aldh4a1 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004612 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00171 all species →	Aldedh	Aldehyde dehydrogenase family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR005931 all species →	Family	Delta-1-pyrroline-5-carboxylate dehydrogenase	Interproscan
IPR016161 all species →	Homologous_superfamily	Aldehyde/histidinol dehydrogenase	Interproscan
IPR016160 all species →	Conserved_site	Aldehyde dehydrogenase, cysteine active site	Interproscan
IPR016162 all species →	Homologous_superfamily	Aldehyde dehydrogenase, N-terminal	Interproscan
IPR050485 all species →	Family	Proline metabolism enzyme	Interproscan
IPR016163 all species →	Homologous_superfamily	Aldehyde dehydrogenase, C-terminal	Interproscan
IPR015590 all species →	Domain	Aldehyde dehydrogenase domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR42862 all species →	DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003842 all species →	Molecular Function	1-pyrroline-5-carboxylate dehydrogenase activity	Interproscan
GO:0010133 all species →	Biological Process	proline catabolic process to glutamate	Interproscan
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0005759 all species →	Cellular Component	mitochondrial matrix	Interproscan
GO:0016620 all species →	Molecular Function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00294	E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase	EC:1.2.1.88	Arginine and proline metabolism	ko00330	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.