Detailed information of gfas1.m1.1786.m1 in Galaxea fascicularis

Genomic Location: Sc0000058:73810...78435
NR annotation: XP_015754936.1, PREDICTED: LON peptidase N-terminal domain and RING finger protein 3-like [Acropora digitifera]
Species Galaxea fascicularis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
D3YY23LON peptidase N-terminal domain and RING finger protein 1 OS=Mus musculus OX=10090 GN=Lonrf1 PE=1 SV=2
Q17RB8LON peptidase N-terminal domain and RING finger protein 1 OS=Homo sapiens OX=9606 GN=LONRF1 PE=1 SV=2
Q496Y0LON peptidase N-terminal domain and RING finger protein 3 OS=Homo sapiens OX=9606 GN=LONRF3 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001318 (this species only) · gene tree & orthology
Ubiquitin familyE3|E3 activity RING|RING · all ubiquitin genes in this species
Ubiquitin familyE3|E3 activity RING|U-box · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02190
all species →
LON_substr_bdgATP-dependent protease La (LON) substrate-binding domain FamilyInterproscan
PF13923
all species →
zf-C3HC4_2Zinc finger, C3HC4 type (RING finger)DomainInterproscan
PF13445
all species →
zf-RING_UBOXRING-type zinc-fingerDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR003111
all species →
DomainLon protease, N-terminal domainInterproscan
IPR015947
all species →
Homologous_superfamilyPUA-like superfamilyInterproscan
IPR011990
all species →
Homologous_superfamilyTetratricopeptide-like helical domain superfamilyInterproscan
IPR046336
all species →
Homologous_superfamilyLon protease, N-terminal domain superfamilyInterproscan
IPR001841
all species →
DomainZinc finger, RING-typeInterproscan
IPR027370
all species →
DomainZinc finger, RING-type, eukaryoticInterproscan
IPR017907
all species →
Conserved_siteZinc finger, RING-type, conserved siteInterproscan
IPR013083
all species →
Homologous_superfamilyZinc finger, RING/FYVE/PHD-typeInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR23327
all species →
RING FINGER PROTEIN 127Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0061630
all species →
Molecular Functionubiquitin protein ligase activityInterproscan
GO:0005515
all species →
Molecular Functionprotein bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for gfas1.m1.1786.m1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of gfas1.m1.1786.m1 across 22 RNA-seq samples of Galaxea fascicularis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

22Samples
22TPM > 0
4Conditions
184.4Max TPM
104.8Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
coral holosome · Control 7 7 112.21 184.41
coral holosome · 30ic treatment 6 6 107.78 134.39
coral holosome · Prometryn (herbicidess) treatment 5 5 96.34 139.66
coral holosome · Prometryn (herbicidess) and 30ic treatment 4 4 97.90 117.30

Per sample · hover a bar for the full sample record

Show the sample table (22 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR27118485 coral holosome · Control coral holosome not recorded Control SRP476288 184.41
SRR27118488 coral holosome · Control coral holosome not recorded Control SRP476288 156.50
SRR27118487 coral holosome · Control coral holosome not recorded Control SRP476288 130.02
SRR27118486 coral holosome · Control coral holosome not recorded Control SRP476288 122.73
SRR27118491 coral holosome · Control coral holosome not recorded Control SRP476288 94.95
SRR27118480 coral holosome · Control coral holosome not recorded Control SRP476288 56.81
SRR27118492 coral holosome · Control coral holosome not recorded Control SRP476288 40.02
SRR27118478 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 134.39
SRR27118476 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 133.71
SRR27118479 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 133.31
SRR27118468 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 111.52
SRR27118477 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 72.15
SRR27118466 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 61.60
SRR27118482 coral holosome · Prometryn (herbicidess) treatment coral holosome not recorded Prometryn (herbicidess) treatment SRP476288 139.66
SRR27118483 coral holosome · Prometryn (herbicidess) treatment coral holosome not recorded Prometryn (herbicidess) treatment SRP476288 108.94
SRR27118481 coral holosome · Prometryn (herbicidess) treatment coral holosome not recorded Prometryn (herbicidess) treatment SRP476288 104.67
SRR27118484 coral holosome · Prometryn (herbicidess) treatment coral holosome not recorded Prometryn (herbicidess) treatment SRP476288 86.93
SRR27118469 coral holosome · Prometryn (herbicidess) treatment coral holosome not recorded Prometryn (herbicidess) treatment SRP476288 41.52
SRR27118472 coral holosome · Prometryn (herbicidess) and 30ic treatment coral holosome not recorded Prometryn (herbicidess) and 30ic treatment SRP476288 117.30
SRR27118475 coral holosome · Prometryn (herbicidess) and 30ic treatment coral holosome not recorded Prometryn (herbicidess) and 30ic treatment SRP476288 103.16
SRR27118489 coral holosome · Prometryn (herbicidess) and 30ic treatment coral holosome not recorded Prometryn (herbicidess) and 30ic treatment SRP476288 92.59
SRR27118490 coral holosome · Prometryn (herbicidess) and 30ic treatment coral holosome not recorded Prometryn (herbicidess) and 30ic treatment SRP476288 78.55

Source: CnidoSite RNA-seq expression matrices (GFASC_TPM, StringTie quantification over 22 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Galaxea fascicularis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated20gfas1.m1.8266.m10.817955191459437
Negatively correlated50gfas1.m1.9184.m1-0.815204897654385

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Galaxea fascicularis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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