Genomic Location: Sc0000089:175083...187611
NR annotation: CAH3120142.1, unnamed protein product [Pocillopora meandrina]
Species Galaxea fascicularis · all data for this species · gene families
| CDS |
| gfas1.m1.2454.m1 |
| Transcript |
| gfas1.m1.2454.m1 |
| Protein |
| gfas1.m1.2454.m1 |
| UniProt accession | Description |
|---|---|
| O14681 | Etoposide-induced protein 2.4 homolog OS=Homo sapiens OX=9606 GN=EI24 PE=1 SV=4 |
| Q61070 | Etoposide-induced protein 2.4 OS=Mus musculus OX=10090 GN=Ei24 PE=1 SV=3 |
| Q4KM77 | Etoposide-induced protein 2.4 homolog OS=Rattus norvegicus OX=10116 GN=Ei24 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0006537 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF07264 all species → | EI24 | Etoposide-induced protein 2.4 (EI24) | Family | Interproscan |
| PF00067 all species → | p450 | Cytochrome P450 | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002401 all species → | Family | Cytochrome P450, E-class, group I | Interproscan |
| IPR039983 all species → | Family | Cholesterol 24-hydroxylase | Interproscan |
| IPR036396 all species → | Homologous_superfamily | Cytochrome P450 superfamily | Interproscan |
| IPR001128 all species → | Family | Cytochrome P450 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR24293 all species → | CYTOCHROME P450 FAMILY 46 SUBFAMILY A | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004497 all species → | Molecular Function | monooxygenase activity | Interproscan |
| GO:0005506 all species → | Molecular Function | iron ion binding | Interproscan |
| GO:0016705 all species → | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Interproscan |
| GO:0020037 all species → | Molecular Function | heme binding | Interproscan |
| GO:0006707 all species → | Biological Process | cholesterol catabolic process | Interproscan |
| GO:0033781 all species → | Molecular Function | cholesterol 24-hydroxylase activity | Interproscan |
gfas1.m1.2454.m1.Transcript abundance of gfas1.m1.2454.m1 across 22 RNA-seq samples of Galaxea fascicularis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| coral holosome · Control | 7 | 5 | 23.98 | 96.92 | |
| coral holosome · 30ic treatment | 6 | 4 | 10.95 | 27.96 | |
| coral holosome · Prometryn (herbicidess) treatment | 5 | 3 | 20.84 | 75.45 | |
| coral holosome · Prometryn (herbicidess) and 30ic treatment | 4 | 4 | 26.05 | 40.34 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR27118491 | coral holosome · Control | coral holosome | not recorded | Control | SRP476288 | 96.92 |
| SRR27118492 | coral holosome · Control | coral holosome | not recorded | Control | SRP476288 | 21.57 |
| SRR27118480 | coral holosome · Control | coral holosome | not recorded | Control | SRP476288 | 20.11 |
| SRR27118487 | coral holosome · Control | coral holosome | not recorded | Control | SRP476288 | 16.01 |
| SRR27118486 | coral holosome · Control | coral holosome | not recorded | Control | SRP476288 | 13.27 |
| SRR27118485 | coral holosome · Control | coral holosome | not recorded | Control | SRP476288 | 0.00 |
| SRR27118488 | coral holosome · Control | coral holosome | not recorded | Control | SRP476288 | 0.00 |
| SRR27118466 | coral holosome · 30ic treatment | coral holosome | not recorded | 30ic treatment | SRP476288 | 27.96 |
| SRR27118476 | coral holosome · 30ic treatment | coral holosome | not recorded | 30ic treatment | SRP476288 | 13.71 |
| SRR27118478 | coral holosome · 30ic treatment | coral holosome | not recorded | 30ic treatment | SRP476288 | 12.89 |
| SRR27118479 | coral holosome · 30ic treatment | coral holosome | not recorded | 30ic treatment | SRP476288 | 11.15 |
| SRR27118468 | coral holosome · 30ic treatment | coral holosome | not recorded | 30ic treatment | SRP476288 | 0.00 |
| SRR27118477 | coral holosome · 30ic treatment | coral holosome | not recorded | 30ic treatment | SRP476288 | 0.00 |
| SRR27118483 | coral holosome · Prometryn (herbicidess) treatment | coral holosome | not recorded | Prometryn (herbicidess) treatment | SRP476288 | 75.45 |
| SRR27118481 | coral holosome · Prometryn (herbicidess) treatment | coral holosome | not recorded | Prometryn (herbicidess) treatment | SRP476288 | 15.13 |
| SRR27118469 | coral holosome · Prometryn (herbicidess) treatment | coral holosome | not recorded | Prometryn (herbicidess) treatment | SRP476288 | 13.62 |
| SRR27118482 | coral holosome · Prometryn (herbicidess) treatment | coral holosome | not recorded | Prometryn (herbicidess) treatment | SRP476288 | 0.00 |
| SRR27118484 | coral holosome · Prometryn (herbicidess) treatment | coral holosome | not recorded | Prometryn (herbicidess) treatment | SRP476288 | 0.00 |
| SRR27118489 | coral holosome · Prometryn (herbicidess) and 30ic treatment | coral holosome | not recorded | Prometryn (herbicidess) and 30ic treatment | SRP476288 | 40.34 |
| SRR27118490 | coral holosome · Prometryn (herbicidess) and 30ic treatment | coral holosome | not recorded | Prometryn (herbicidess) and 30ic treatment | SRP476288 | 31.85 |
| SRR27118475 | coral holosome · Prometryn (herbicidess) and 30ic treatment | coral holosome | not recorded | Prometryn (herbicidess) and 30ic treatment | SRP476288 | 20.42 |
| SRR27118472 | coral holosome · Prometryn (herbicidess) and 30ic treatment | coral holosome | not recorded | Prometryn (herbicidess) and 30ic treatment | SRP476288 | 11.59 |
Source: CnidoSite RNA-seq expression matrices (GFASC_TPM,
StringTie quantification over 22 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Galaxea fascicularis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 28 | gfas1.m1.9681.m1 | 0.921953556989398 |
| Negatively correlated | 9 | gfas1.m1.15223.m1 | -0.794285494139687 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Galaxea fascicularis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
