Detailed information of gfas1.m1.7392.m1 in Galaxea fascicularis

Genomic Location: Sc0000524:18099...25861
NR annotation: CAH3036850.1, unnamed protein product, partial [Porites lobata]
Species Galaxea fascicularis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q08BA6RNA demethylase ALKBH5 OS=Danio rerio OX=7955 GN=alkbh5 PE=1 SV=1
Q6GPB5RNA demethylase ALKBH5 OS=Xenopus laevis OX=8355 GN=alkbh5 PE=2 SV=1
D3ZKD3RNA demethylase ALKBH5 OS=Rattus norvegicus OX=10116 GN=Alkbh5 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0008303 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF13532
all species →
2OG-FeII_Oxy_22OG-Fe(II) oxygenase superfamilyDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR037151
all species →
Homologous_superfamilyAlpha-ketoglutarate-dependent dioxygenase AlkB-like superfamilyInterproscan
IPR032860
all species →
FamilyRNA demethylase ALKBH5Interproscan
IPR027450
all species →
DomainAlpha-ketoglutarate-dependent dioxygenase AlkB-likeInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR32074
all species →
RNA DEMETHYLASE ALKBH5Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0006397
all species →
Biological ProcessmRNA processingInterproscan
GO:0006406
all species →
Biological ProcessmRNA export from nucleusInterproscan
GO:0035515
all species →
Molecular Functionoxidative RNA demethylase activityInterproscan
GO:0035553
all species →
Biological Processobsolete oxidative single-stranded RNA demethylationInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K10767ALKBH5; mRNA N6-methyladenine demethylaseEC:1.14.11.53
Messenger RNA biogenesisko03019deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of gfas1.m1.7392.m1 across 22 RNA-seq samples of Galaxea fascicularis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

22Samples
18TPM > 0
4Conditions
51.2Max TPM
26.5Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
coral holosome · Control 7 6 31.52 51.17
coral holosome · 30ic treatment 6 5 21.02 31.12
coral holosome · Prometryn (herbicidess) treatment 5 3 20.88 42.75
coral holosome · Prometryn (herbicidess) and 30ic treatment 4 4 33.06 38.35

Per sample · hover a bar for the full sample record

Show the sample table (22 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR27118492 coral holosome · Control coral holosome not recorded Control SRP476288 51.17
SRR27118491 coral holosome · Control coral holosome not recorded Control SRP476288 49.11
SRR27118480 coral holosome · Control coral holosome not recorded Control SRP476288 40.27
SRR27118487 coral holosome · Control coral holosome not recorded Control SRP476288 28.94
SRR27118486 coral holosome · Control coral holosome not recorded Control SRP476288 25.69
SRR27118488 coral holosome · Control coral holosome not recorded Control SRP476288 25.49
SRR27118485 coral holosome · Control coral holosome not recorded Control SRP476288 0.00
SRR27118476 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 31.12
SRR27118479 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 28.81
SRR27118478 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 28.21
SRR27118466 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 27.53
SRR27118477 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 10.43
SRR27118468 coral holosome · 30ic treatment coral holosome not recorded 30ic treatment SRP476288 0.00
SRR27118469 coral holosome · Prometryn (herbicidess) treatment coral holosome not recorded Prometryn (herbicidess) treatment SRP476288 42.75
SRR27118484 coral holosome · Prometryn (herbicidess) treatment coral holosome not recorded Prometryn (herbicidess) treatment SRP476288 35.23
SRR27118481 coral holosome · Prometryn (herbicidess) treatment coral holosome not recorded Prometryn (herbicidess) treatment SRP476288 26.40
SRR27118482 coral holosome · Prometryn (herbicidess) treatment coral holosome not recorded Prometryn (herbicidess) treatment SRP476288 0.00
SRR27118483 coral holosome · Prometryn (herbicidess) treatment coral holosome not recorded Prometryn (herbicidess) treatment SRP476288 0.00
SRR27118475 coral holosome · Prometryn (herbicidess) and 30ic treatment coral holosome not recorded Prometryn (herbicidess) and 30ic treatment SRP476288 38.35
SRR27118472 coral holosome · Prometryn (herbicidess) and 30ic treatment coral holosome not recorded Prometryn (herbicidess) and 30ic treatment SRP476288 33.94
SRR27118490 coral holosome · Prometryn (herbicidess) and 30ic treatment coral holosome not recorded Prometryn (herbicidess) and 30ic treatment SRP476288 31.26
SRR27118489 coral holosome · Prometryn (herbicidess) and 30ic treatment coral holosome not recorded Prometryn (herbicidess) and 30ic treatment SRP476288 28.68

Source: CnidoSite RNA-seq expression matrices (GFASC_TPM, StringTie quantification over 22 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Galaxea fascicularis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated30gfas1.m1.2590.m10.896048025592214
Negatively correlated23gfas1.m1.17742.m1-0.813278696176966

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Galaxea fascicularis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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