Genomic Location: scaffold273:388655...465375
NR annotation: XP_027053924.1, ADAM 17-like protease [Pocillopora damicornis]
| CDS | |||||
| scaffold273.g11.t2 | |||||
| Transcript |
| scaffold273.g11.t2 |
| Protein |
| scaffold273.g11.t2 |
| Uniprot term | Description |
|---|---|
| Q9VAC5 | ADAM 17-like protease OS=Drosophila melanogaster OX=7227 GN=Tace PE=2 SV=2 |
| P78536 | Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ADAM17 PE=1 SV=1 |
| O77636 | Disintegrin and metalloproteinase domain-containing protein 17 OS=Sus scrofa OX=9823 GN=ADAM17 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13574 | Reprolysin_2 | Metallo-peptidase family M12B Reprolysin-like | Domain | Interproscan |
| PF00200 | Disintegrin | Disintegrin | Domain | Interproscan |
| PF16698 | ADAM17_MPD | Membrane-proximal domain, switch, for ADAM17 | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001762 | Domain | Disintegrin domain | Interproscan |
| IPR051489 | Family | Disintegrin and Metalloproteinase Domain-Containing | Interproscan |
| IPR001590 | Domain | Peptidase M12B, ADAM/reprolysin | Interproscan |
| IPR036436 | Homologous_superfamily | Disintegrin domain superfamily | Interproscan |
| IPR024079 | Homologous_superfamily | Metallopeptidase, catalytic domain superfamily | Interproscan |
| IPR032029 | Domain | ADAM17, membrane-proximal domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45702 | ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004222 | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0006509 | Biological Process | membrane protein ectodomain proteolysis | Interproscan |
| GO:0007219 | Biological Process | Notch signaling pathway | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0008237 | Molecular Function | metallopeptidase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K06059 | ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 | EC:3.4.24.86 | CD molecules | ko04090 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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