Genomic Location: scaffold51:2681672...2765171
NR annotation: XP_047136909.1, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X2 [Hydra vulgaris]
| CDS | |||||
| scaffold51.g76.t1 | |||||
| Transcript |
| scaffold51.g76.t1 |
| Protein |
| scaffold51.g76.t1 |
| Uniprot term | Description |
|---|---|
| P0C1Q2 | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Mus musculus OX=10090 GN=Pde11a PE=1 SV=1 |
| Q9HCR9 | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Homo sapiens OX=9606 GN=PDE11A PE=1 SV=2 |
| Q1KKS3 | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Takifugu rubripes OX=31033 GN=pde11a PE=3 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00233 | PDEase_I | 3'5'-cyclic nucleotide phosphodiesterase | Domain | Interproscan |
| PF13185 | GAF_2 | GAF domain | Domain | Interproscan |
| PF01590 | GAF | GAF domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR023174 | Conserved_site | 3'5'-cyclic nucleotide phosphodiesterase, conserved site | Interproscan |
| IPR029016 | Homologous_superfamily | GAF-like domain superfamily | Interproscan |
| IPR002073 | Domain | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | Interproscan |
| IPR003018 | Domain | GAF domain | Interproscan |
| IPR023088 | Family | 3'5'-cyclic nucleotide phosphodiesterase | Interproscan |
| IPR003607 | Domain | HD/PDEase domain | Interproscan |
| IPR036971 | Homologous_superfamily | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11347 | CYCLIC NUCLEOTIDE PHOSPHODIESTERASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0008081 | Molecular Function | phosphoric diester hydrolase activity | Interproscan |
| GO:0004114 | Molecular Function | 3',5'-cyclic-nucleotide phosphodiesterase activity | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0004118 | Molecular Function | 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity | Interproscan |
| GO:0010754 | Biological Process | negative regulation of cGMP-mediated signaling | Interproscan |
| GO:0043951 | Biological Process | negative regulation of cAMP-mediated signaling | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K13298 | PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 | EC:3.1.4.17 EC:3.1.4.35 | Cushing syndrome | ko04934 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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