Gene detail

Detailed information of scaffold72.g32.t1 in Morbakka virulenta

Genomic Location: scaffold72:1719939...1756833
NR annotation: XP_047139218.1, C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Hydra vulgaris]

Gene Structure

More details in Jbrowse

Sequence

CDS

Transcript

scaffold72.g32.t1

AAGCCACAGGAAATCAGAAACCATCATGAATGTCGTTCACTTTAGCCTTTGAAAAAGAACAAAGTTAACACTGGACGGTGCATGCAATCCACTCATTTTCAGCTGATCTCAAGATGGCTCAGATTATCAAGGGAAACTTGATATCAAGGGAAATTCGTGAAGCAGTTGGACGAGAAACAGCAGCTATTAAGGAGCAATATGGCATGAAACCAGGATTGGCTGTTGTACAGGTTGGCAACAGGGAGGATTCTAATGTGTATGTCAAGAAAAAGATCCAGAATGCAACTGAGCTTGGTATGCATGCTGAACACCGAAAGCTGCCGCAAACTGTTGAAGAGGCAGAGGTTCTTGAGACTATTGACGAGCTAAACGAAGACCCAAATATCCATGGAATTATAGTTCAACTGCCTTTAGATTCAGTTAATCCGATTGACTCAGCAGCTTGCACCAATAGAGTTTTACCGGAAAAGGATGTGGATGGCATAAATGACATTAATGCTGGACGACTAGCCAGAGGTCAGCTGGACAATTGCTTTGTATGCTGTACCCCCAAAGGATGCCTTGAGCTCATTAAGGGAACAGGTGCACCGGTAAAAGGACAGAATGCAGTTGTTTTGGGCAGAAGCAAAATAGTGGGATCACCAATGGCAAATTTATTAACTTGGCATCATGCAACAGTCACAATTTGCCATTCAAAAACAAGAGATCTTCCTGACGTGGTTCGCAATGCTGATATTGTTGTTGCTGCTGTTGGGCAAGTCAATATGGTTAAGGGGAGTTGGATTAAACCAGGATCGGTTGTTATTGACTGTGGAATTACTGCAGTGCCAGATGCAAGTAAAAAGAGTGGACAGCGGCTAGTAGGCGATGTAGATTATGCGGAATGTCAGCCGATAGCTGGATGGATAACACCAGTTCCTGGAGGTGTTGGTCCTATGACAGTGGCCATGTTGCTGCAAAATACGGTTGAAAGCTGCAGACGTTTCGCTCAGACCAGGAAAACACAACAAGCTGGTCTGCATGGCGCTGTTGAGGCTTTGAAACTGGTTAAACGCCTTGCAAGATTTAGGTTTTGAGTGTTTTAAGGAATCATGAATATCTGTTTGCACGATATTGTCTTTGTCAAAAGTTATTTGATTTTGAATTCATTTTTTTATGTGGTTGGCAACGCTAACTATTAGGTTTCGTTAACGACAAGAAGCCCTATTCAGAGTGATATGTGTTTATATACACACTTCTGCATCGCATAGATGTAGACTTGCTTGATTGCTGTGATTTTGTTTTTAATAGTCAAATTAATCACTTGATTGCTGTGATTATCTCTTTAGATAGCCTAATTAATCCGTCGTGAAGAATCATGTAATTATGACTAAGGGTTGGAATTTTCAAGCGAGGTTCATGTTTGTTACACTAGTTCCAATTCAGTGGATGTGACCGCGTGGAATTTTTTTTTTTCGGAGGTTTTTGTTGTCTGAATGTGAGGAAAAGTGAAATTTTGATTTCACTTTGAACTGGAACAGAAGCCAGCATGCCTACTAGACTCGAATGGGTTATTAATTAATAAGGCGAGATTCTTTTTTGCCTAAGGGGTTATTTCCTTTTCATATATGGCTGTTTAATTTTCAAACAACTCAGGCTAGTTAATACGCTTAAGATATTACCTATGGTTCAGATGCAGAATAGTGGTTGATCaaataaacgatttgttgttcagatcttgaatgtcgcagttcaaaacgctttcattttgttcgaaagctttttttcgatctcgtccggagcatgacatcagaacgacagagcaaaaactattcggtattttattaataaggaaagaaaagGTAGATTTTAATACATCACCCTACTTTTTGTGATTGTTATCACaaacatctgaagactttttacagtacattttgtataacaaattggaggcgatgaaaactagataaagatagcctccagtgctcctggggagagtacagggataactctactaatGGCAAATAACAGTTTAGCCCCTAGAGATACATACTCGTTTTTGCTATCAAATATAGTCCCTTTTTTCCTATCTTTTTTGCTATTCTACGCACATTGTATCACATTAACACATATTCATGAACGTAGAGGTCTGGGGCCTACATATATCCTTAttaagcacgagcaaatattggagcgcttctaaatctttgtattttccttgatcttgtttttggacgttttatcttttcgttctagacaatttacataataatagactagtcatttaatgcgtgccctgtacgtgtgctccattgtgtaatggaacaataagttggtcaattcttaaactgagttgaatatagacctaatgggcactcatccatgtattaagtgaagttcagagttctttttatagacacttctttgctcagtaatgaaataaaatgaaataaataaaatactaagctcgcgcttatagactgaaggtttttcagtcttgttTTCTATATTTTTTCCTATTCCACGTACGTTGTATTACATTAACACATATTCATGAACGTAGAGGTCTGGGGCNTGATTGTTATCACaaacatctgaagactttttacagtacattttgtataacaaattggaggcgatgaaaactagataaagatagcctccagtgctcctggggagagtacagggataactctactaatGGCAAATAACAGTTTAGCCCCTAGAGATACATACTCGTTTTTGCTATCAAATATAGTCCCTTTTTTCCTATCTTTTTTGCTATTCTACGCACATTGTATCACATTAACACATATTCATGAACGTAGAGGTCTGGGGCCTACATATATCCTTAttaagcacgagcaaatattggagcgcttctaaatctttgtattttccttgatcttgtttttggacgttttatcttttcgttctagacaatttacataataatagactagtcatttaatgcgtgccctgtacgtgtgctccatt

Protein

Uniprot

Uniprot term	Description
O96553	C-1-tetrahydrofolate synthase, cytoplasmic OS=Drosophila melanogaster OX=7227 GN=pug PE=2 SV=4
P11586	C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4
P27653	C-1-tetrahydrofolate synthase, cytoplasmic OS=Rattus norvegicus OX=10116 GN=Mthfd1 PE=1 SV=3

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02882	THF_DHG_CYH_C	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain	Domain	Interproscan
PF00763	THF_DHG_CYH	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR020631	Domain	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain	Interproscan
IPR000672	Family	Tetrahydrofolate dehydrogenase/cyclohydrolase	Interproscan
IPR020630	Domain	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	Interproscan
IPR036291	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan
IPR020867	Conserved_site	Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site	Interproscan
IPR046346	Homologous_superfamily	Aminoacid dehydrogenase-like, N-terminal domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR48099	C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004488	Molecular Function	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Interproscan
GO:0004477	Molecular Function	methenyltetrahydrofolate cyclohydrolase activity	Interproscan
GO:0005829	Cellular Component	cytosol	Interproscan
GO:0035999	Biological Process	tetrahydrofolate interconversion	Interproscan
GO:0003824	Molecular Function	catalytic activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K01491	folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase	EC:1.5.1.5 EC:3.5.4.9	One carbon pool by folate	ko00670	deepkoala