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This orthogroup contains 1,181 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,181 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12411 | CYSTEINE PROTEASE FAMILY C1-RELATED | 976 / 1,181 | 82.6% | 99.1% of 985 | ≥80% support |
| Pfam | PF00112 | Peptidase_C1 — Papain family cysteine protease | 983 / 1,181 | 83.2% | 96.6% of 1,018 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 985 / 1,181 | 83.4% | 99.5% of 990 | ≥80% support |
| GO | GO:0008234 Molecular Function | cysteine-type peptidase activity | 983 / 1,181 | 83.2% | 99.3% of 990 | ≥80% support |
| GO | GO:0004197 Molecular Function | cysteine-type endopeptidase activity | 976 / 1,181 | 82.6% | 98.6% of 990 | ≥80% support |
| GO | GO:0005615 Cellular Component | extracellular space | 976 / 1,181 | 82.6% | 98.6% of 990 | ≥80% support |
| GO | GO:0005764 Cellular Component | lysosome | 976 / 1,181 | 82.6% | 98.6% of 990 | ≥80% support |
| GO | GO:0051603 Biological Process | proteolysis involved in protein catabolic process | 976 / 1,181 | 82.6% | 98.6% of 990 | ≥80% support |
| Pfam | PF08246 | Inhibitor_I29 — Cathepsin propeptide inhibitor domain (I29) | 911 / 1,181 | 77.1% | 89.5% of 1,018 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinia mediterranea | ENSQPTP00000027389.1 | XP_031549846.1 | counting factor associated protein D-like [Actinia tenebrosa] | P43235 Cathepsin K OS=Homo sapiens OX=9606 GN=CTSK PE=1 SV=1 | JBrowse |
| Actinia mediterranea | ENSQPTP00000028827.1 | XP_031550457.1 | counting factor associated protein D-like [Actinia tenebrosa] | Q54TR1 Counting factor associated protein D OS=Dictyostelium discoi | JBrowse |
| Actinia mediterranea | ENSQPTP00000029915.1 | none | – | JBrowse | |
| Actinia mediterranea | ENSQPTP00000029921.1 | XP_031549756.1 | cysteine proteinase-like [Actinia tenebrosa] | A0A1S4F2V5 Cathepsin L-like peptidase OS=Aedes aegypti OX=7159 PE=1 SV= | JBrowse |
| Actinia mediterranea | ENSQPTP00000030944.1 | XP_031549819.1 | digestive cysteine proteinase 2-like [Actinia tenebrosa] | Q54TR1 Counting factor associated protein D OS=Dictyostelium discoi | JBrowse |
| Actinia mediterranea | ENSQPTP00000031378.1 | XP_031549821.1 | cathepsin K-like [Actinia tenebrosa] | A0A1S4F2V5 Cathepsin L-like peptidase OS=Aedes aegypti OX=7159 PE=1 SV= | JBrowse |
| Actinia mediterranea | ENSQPTP00000032152.1 | none | – | JBrowse | |
| Actinia mediterranea | ENSQPTP00000032163.1 | XP_031549754.1 | counting factor associated protein D-like isoform X1 [Actinia tenebrosa] | O70370 Cathepsin S OS=Mus musculus OX=10090 GN=Ctss PE=1 SV=2 | JBrowse |
| Actinia mediterranea | ENSQPTP00000068097.1 | none | – | JBrowse | |
| Actinia mediterranea | ENSQPTP00000068103.1 | XP_031549754.1 | counting factor associated protein D-like isoform X1 [Actinia tenebrosa] | O70370 Cathepsin S OS=Mus musculus OX=10090 GN=Ctss PE=1 SV=2 | JBrowse |
| Actinia mediterranea | ENSQPTP00000068392.1 | XP_031549821.1 | cathepsin K-like [Actinia tenebrosa] | A0A1S4F2V5 Cathepsin L-like peptidase OS=Aedes aegypti OX=7159 PE=1 SV= | JBrowse |
| Actinia mediterranea | ENSQPTP00000069375.1 | XP_031549846.1 | counting factor associated protein D-like [Actinia tenebrosa] | P43235 Cathepsin K OS=Homo sapiens OX=9606 GN=CTSK PE=1 SV=1 | JBrowse |
| Actinia mediterranea | ENSQPTP00000069619.1 | XP_031550457.1 | counting factor associated protein D-like [Actinia tenebrosa] | Q54TR1 Counting factor associated protein D OS=Dictyostelium discoi | JBrowse |
| Actinia mediterranea | ENSQPTP00000070738.1 | XP_031549819.1 | digestive cysteine proteinase 2-like [Actinia tenebrosa] | Q54TR1 Counting factor associated protein D OS=Dictyostelium discoi | JBrowse |
| Actinia mediterranea | ENSQPTP00000070845.1 | none | – | JBrowse | |
| Actinia mediterranea | ENSQPTP00000070852.1 | XP_031549756.1 | cysteine proteinase-like [Actinia tenebrosa] | A0A1S4F2V5 Cathepsin L-like peptidase OS=Aedes aegypti OX=7159 PE=1 SV= | JBrowse |