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This orthogroup contains 1,175 genes from 146 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,175 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23220 | INTEGRIN ALPHA | 971 / 1,175 | 82.6% | 99.5% of 976 | ≥80% support |
| GO | GO:0008305 Cellular Component | integrin complex | 972 / 1,175 | 82.7% | 99.7% of 975 | ≥80% support |
| GO | GO:0009897 Cellular Component | external side of plasma membrane | 972 / 1,175 | 82.7% | 99.7% of 975 | ≥80% support |
| GO | GO:0005178 Molecular Function | integrin binding | 971 / 1,175 | 82.6% | 99.6% of 975 | ≥80% support |
| GO | GO:0007160 Biological Process | cell-matrix adhesion | 971 / 1,175 | 82.6% | 99.6% of 975 | ≥80% support |
| GO | GO:0007229 Biological Process | integrin-mediated signaling pathway | 971 / 1,175 | 82.6% | 99.6% of 975 | ≥80% support |
| GO | GO:0033627 Biological Process | cell adhesion mediated by integrin | 971 / 1,175 | 82.6% | 99.6% of 975 | ≥80% support |
| GO | GO:0098609 Biological Process | cell-cell adhesion | 971 / 1,175 | 82.6% | 99.6% of 975 | ≥80% support |
| Pfam | PF20806 | Integrin_A_Ig_3 — Integrin alpha Ig-like domain 3 | 730 / 1,175 | 62.1% | 82.3% of 887 | ≥50% support |
| Pfam | PF01839 | FG-GAP | 719 / 1,175 | 61.2% | 81.1% of 887 | ≥50% support |
| Pfam | PF20805 | Integrin_A_Ig_2 — Integrin alpha Ig-like domain 2 | 689 / 1,175 | 58.6% | 77.7% of 887 | ≥50% support |
| Pfam | PF08441 | Integrin_A_Ig_1 — Integrin alpha Ig-like domain 1 | 641 / 1,175 | 54.6% | 72.3% of 887 | ≥50% support |
| GO | GO:0007155 Biological Process | cell adhesion | 761 / 1,175 | 64.8% | 78.1% of 975 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
