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This orthogroup contains 372 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 372 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11561 | PHOSPHOENOLPYRUVATE CARBOXYKINASE | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| Pfam | PF00821 | PEPCK_GTP — Phosphoenolpyruvate carboxykinase C-terminal P-loop domain | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| Pfam | PF17297 | PEPCK_N — Phosphoenolpyruvate carboxykinase N-terminal domain | 315 / 372 | 84.7% | 94.3% of 334 | ≥80% support |
| GO | GO:0004611 Molecular Function | phosphoenolpyruvate carboxykinase activity | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| GO | GO:0004613 Molecular Function | phosphoenolpyruvate carboxykinase (GTP) activity | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| GO | GO:0005525 Molecular Function | GTP binding | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| GO | GO:0005829 Cellular Component | cytosol | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| GO | GO:0006094 Biological Process | gluconeogenesis | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| GO | GO:0017076 Molecular Function | purine nucleotide binding | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| GO | GO:0019543 Biological Process | propionate catabolic process | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| GO | GO:0030145 Molecular Function | manganese ion binding | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| GO | GO:0033993 Biological Process | response to lipid | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| GO | GO:0042594 Biological Process | response to starvation | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| GO | GO:0046327 Biological Process | glycerol biosynthetic process from pyruvate | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| GO | GO:0071333 Biological Process | cellular response to glucose stimulus | 334 / 372 | 89.8% | 100.0% of 334 | ≥80% support |
| KEGG | K01596 | E4.1.1.32, pckA, PCK — Insulin resistance | 311 / 372 | 83.6% | 99.4% of 313 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinia mediterranea | ENSQPTP00000020643.1 | XP_031568381.1 | phosphoenolpyruvate carboxykinase, cytosolic [GTP]-like isoform X1 [Actinia tenebrosa] | P07379 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] OS=Rattus | JBrowse |
| Actinia mediterranea | ENSQPTP00000058935.1 | XP_031568381.1 | phosphoenolpyruvate carboxykinase, cytosolic [GTP]-like isoform X1 [Actinia tenebrosa] | P07379 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] OS=Rattus | JBrowse |
