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This orthogroup contains 305 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 305 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0003677 Molecular Function | DNA binding | 247 / 305 | 81.0% | 97.6% of 253 | ≥80% support |
| PANTHER | PTHR10629 | CYTOSINE-SPECIFIC METHYLTRANSFERASE | 233 / 305 | 76.4% | 99.2% of 235 | ≥50% support |
| Pfam | PF00145 | DNA_methylase — C-5 cytosine-specific DNA methylase | 214 / 305 | 70.2% | 77.5% of 276 | ≥50% support |
| Pfam | PF01426 | BAH | 210 / 305 | 68.9% | 76.1% of 276 | ≥50% support |
| Pfam | PF12047 | DNMT1-RFD — Cytosine specific DNA methyltransferase replication foci domain | 187 / 305 | 61.3% | 67.8% of 276 | ≥50% support |
| Pfam | PF02008 | zf-CXXC — CXXC zinc finger domain | 178 / 305 | 58.4% | 64.5% of 276 | ≥50% support |
| GO | GO:0003886 Molecular Function | DNA (cytosine-5-)-methyltransferase activity | 221 / 305 | 72.5% | 87.4% of 253 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 220 / 305 | 72.1% | 87.0% of 253 | ≥50% support |
| GO | GO:0008168 Molecular Function | methyltransferase activity | 214 / 305 | 70.2% | 84.6% of 253 | ≥50% support |
| GO | GO:0003682 Molecular Function | chromatin binding | 212 / 305 | 69.5% | 83.8% of 253 | ≥50% support |
| GO | GO:0010216 Biological Process | obsolete negative regulation of gene expression via chromosomal DNA cytosine methylation | 206 / 305 | 67.5% | 81.4% of 253 | ≥50% support |
| GO | GO:0010424 Biological Process | obsolete DNA methylation on cytosine within a CG sequence | 206 / 305 | 67.5% | 81.4% of 253 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 180 / 305 | 59.0% | 71.2% of 253 | ≥50% support |
| GO | GO:0006346 Biological Process | DNA methylation-dependent constitutive heterochromatin formation | 154 / 305 | 50.5% | 60.9% of 253 | ≥50% support |
| KEGG | K00558 | DNMT1, dcm — Prokaryotic defense system | 176 / 305 | 57.7% | 97.2% of 181 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinia mediterranea | ENSQPTP00000009165.1 | XP_031560018.1 | DNA (cytosine-5)-methyltransferase 1-like [Actinia tenebrosa] | Q27746 DNA (cytosine-5)-methyltransferase PliMCI OS=Paracentrotus l | JBrowse |
| Actinia mediterranea | ENSQPTP00000049639.1 | XP_031560018.1 | DNA (cytosine-5)-methyltransferase 1-like [Actinia tenebrosa] | Q27746 DNA (cytosine-5)-methyltransferase PliMCI OS=Paracentrotus l | JBrowse |
