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This orthogroup contains 265 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 265 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF19431 | MEKK4_N — MEKK4 N-terminal | 218 / 265 | 82.3% | 91.2% of 239 | ≥80% support |
| GO | GO:0000165 Biological Process | MAPK cascade | 218 / 265 | 82.3% | 90.8% of 240 | ≥80% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 213 / 265 | 80.4% | 88.8% of 240 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 213 / 265 | 80.4% | 88.8% of 240 | ≥80% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 213 / 265 | 80.4% | 88.8% of 240 | ≥80% support |
| PANTHER | PTHR48016 | MAP KINASE KINASE KINASE SSK2-RELATED-RELATED | 207 / 265 | 78.1% | 96.3% of 215 | ≥50% support |
| Pfam | PF00069 | Pkinase — Protein kinase domain | 211 / 265 | 79.6% | 88.3% of 239 | ≥50% support |
| KEGG | K04428 | MAP3K4, MEKK4 — Protein kinases | 162 / 265 | 61.1% | 98.2% of 165 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinia mediterranea | ENSQPTP00000014858.1 | XP_031553106.1 | mitogen-activated protein kinase kinase kinase 4-like isoform X1 [Actinia tenebrosa] | Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 OS=Homo sap | JBrowse |
| Actinia mediterranea | ENSQPTP00000055497.1 | XP_031553106.1 | mitogen-activated protein kinase kinase kinase 4-like isoform X1 [Actinia tenebrosa] | Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 OS=Homo sap | JBrowse |
