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This orthogroup contains 263 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 263 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45747 | HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) | 220 / 263 | 83.7% | 98.2% of 224 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 221 / 263 | 84.0% | 99.1% of 223 | ≥80% support |
| GO | GO:0003682 Molecular Function | chromatin binding | 220 / 263 | 83.7% | 98.7% of 223 | ≥80% support |
| GO | GO:0006338 Biological Process | chromatin remodeling | 220 / 263 | 83.7% | 98.7% of 223 | ≥80% support |
| GO | GO:0031507 Biological Process | heterochromatin formation | 220 / 263 | 83.7% | 98.7% of 223 | ≥80% support |
| GO | GO:0035098 Cellular Component | ESC/E(Z) complex | 220 / 263 | 83.7% | 98.7% of 223 | ≥80% support |
| GO | GO:0042054 Molecular Function | histone methyltransferase activity | 220 / 263 | 83.7% | 98.7% of 223 | ≥80% support |
| GO | GO:0046976 Molecular Function | histone H3K27 methyltransferase activity | 220 / 263 | 83.7% | 98.7% of 223 | ≥80% support |
| Pfam | PF00856 | SET | 197 / 263 | 74.9% | 90.8% of 217 | ≥50% support |
| Pfam | PF18264 | preSET_CXC — CXC domain | 194 / 263 | 73.8% | 89.4% of 217 | ≥50% support |
| Pfam | PF21358 | Ezh2_MCSS — Ezh2, MCSS domain | 186 / 263 | 70.7% | 85.7% of 217 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 198 / 263 | 75.3% | 88.8% of 223 | ≥50% support |
| KEGG | K11430 | EZH2 — Chromosome and associated proteins | 183 / 263 | 69.6% | 96.3% of 190 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinia mediterranea | ENSQPTP00000001611.1 | XP_031552852.1 | histone-lysine N-methyltransferase EZH2-like [Actinia tenebrosa] | Q4V863 Histone-lysine N-methyltransferase EZH2 OS=Xenopus laevis OX | JBrowse |
| Actinia mediterranea | ENSQPTP00000040420.1 | XP_031552852.1 | histone-lysine N-methyltransferase EZH2-like [Actinia tenebrosa] | Q4V863 Histone-lysine N-methyltransferase EZH2 OS=Xenopus laevis OX | JBrowse |
