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This orthogroup contains 207 genes from 129 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 207 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00619 | CARD — Caspase recruitment domain | 172 / 207 | 83.1% | 100.0% of 172 | ≥80% support |
| GO | GO:0042981 Biological Process | regulation of apoptotic process | 174 / 207 | 84.1% | 100.0% of 174 | ≥80% support |
| PANTHER | PTHR34920 | B-CELL LYMPHOMA/LEUKEMIA 10 | 133 / 207 | 64.3% | 79.6% of 167 | ≥50% support |
| GO | GO:0002250 Biological Process | adaptive immune response | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0003713 Molecular Function | transcription coactivator activity | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0006915 Biological Process | apoptotic process | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0007249 Biological Process | canonical NF-kappaB signal transduction | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0019209 Molecular Function | kinase activator activity | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0032449 Cellular Component | CBM complex | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0043422 Molecular Function | protein kinase B binding | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0051059 Molecular Function | NF-kappaB binding | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0051092 Biological Process | positive regulation of NF-kappaB transcription factor activity | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:2001238 Biological Process | positive regulation of extrinsic apoptotic signaling pathway | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinia mediterranea | ENSQPTP00000017922.1 | XP_031573626.1 | tight junction protein ZO-1-like isoform X6 [Actinia tenebrosa] | – | JBrowse |
| Actinia mediterranea | ENSQPTP00000020651.1 | XP_031573626.1 | tight junction protein ZO-1-like isoform X6 [Actinia tenebrosa] | – | JBrowse |
| Actinia mediterranea | ENSQPTP00000058095.1 | XP_031573626.1 | tight junction protein ZO-1-like isoform X6 [Actinia tenebrosa] | – | JBrowse |
| Actinia mediterranea | ENSQPTP00000060296.1 | XP_031573626.1 | tight junction protein ZO-1-like isoform X6 [Actinia tenebrosa] | – | JBrowse |
