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This orthogroup contains 187 genes from 120 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 187 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR18945 | NEUROTRANSMITTER GATED ION CHANNEL | 168 / 187 | 89.8% | 98.8% of 170 | ≥80% support |
| Pfam | PF02932 | Neur_chan_memb — Neurotransmitter-gated ion-channel transmembrane region | 161 / 187 | 86.1% | 93.6% of 172 | ≥80% support |
| Pfam | PF02931 | Neur_chan_LBD — Neurotransmitter-gated ion-channel ligand binding domain | 154 / 187 | 82.4% | 89.5% of 172 | ≥80% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 176 / 187 | 94.1% | 100.0% of 176 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 176 / 187 | 94.1% | 100.0% of 176 | ≥80% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 169 / 187 | 90.4% | 96.0% of 176 | ≥80% support |
| GO | GO:0034220 Biological Process | monoatomic ion transmembrane transport | 169 / 187 | 90.4% | 96.0% of 176 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 169 / 187 | 90.4% | 96.0% of 176 | ≥80% support |
| GO | GO:0004888 Molecular Function | transmembrane signaling receptor activity | 169 / 187 | 90.4% | 96.0% of 176 | ≥80% support |
| GO | GO:0007268 Biological Process | chemical synaptic transmission | 168 / 187 | 89.8% | 95.5% of 176 | ≥80% support |
| GO | GO:0030594 Molecular Function | neurotransmitter receptor activity | 168 / 187 | 89.8% | 95.5% of 176 | ≥80% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 168 / 187 | 89.8% | 95.5% of 176 | ≥80% support |
| GO | GO:0042391 Biological Process | regulation of membrane potential | 168 / 187 | 89.8% | 95.5% of 176 | ≥80% support |
| GO | GO:0043005 Cellular Component | neuron projection | 168 / 187 | 89.8% | 95.5% of 176 | ≥80% support |
| GO | GO:0045202 Cellular Component | synapse | 168 / 187 | 89.8% | 95.5% of 176 | ≥80% support |
| GO | GO:0050877 Biological Process | nervous system process | 168 / 187 | 89.8% | 95.5% of 176 | ≥80% support |
| GO | GO:1904315 Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | 168 / 187 | 89.8% | 95.5% of 176 | ≥80% support |
| GO | GO:0005231 Molecular Function | excitatory extracellular ligand-gated monoatomic ion channel activity | 168 / 187 | 89.8% | 95.5% of 176 | ≥80% support |
| GO | GO:0005230 Molecular Function | extracellular ligand-gated monoatomic ion channel activity | 154 / 187 | 82.4% | 87.5% of 176 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinia mediterranea | ENSQPTP00000037000.1 | XP_031569728.1 | neuronal acetylcholine receptor subunit beta-4-like [Actinia tenebrosa] | P30926 Neuronal acetylcholine receptor subunit beta-4 OS=Homo sapie | JBrowse |
| Actinia mediterranea | ENSQPTP00000076595.1 | XP_031569728.1 | neuronal acetylcholine receptor subunit beta-4-like [Actinia tenebrosa] | P30926 Neuronal acetylcholine receptor subunit beta-4 OS=Homo sapie | JBrowse |
