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This orthogroup contains 301 genes from 136 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 301 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR22748 | AP ENDONUCLEASE | 253 / 301 | 84.1% | 97.3% of 260 | ≥80% support |
| Pfam | PF03372 | Exo_endo_phos — Endonuclease/Exonuclease/phosphatase family | 258 / 301 | 85.7% | 100.0% of 258 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 260 / 301 | 86.4% | 100.0% of 260 | ≥80% support |
| GO | GO:0008311 Molecular Function | double-stranded DNA 3'-5' DNA exonuclease activity | 259 / 301 | 86.1% | 99.6% of 260 | ≥80% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 258 / 301 | 85.7% | 99.2% of 260 | ≥80% support |
| GO | GO:0004518 Molecular Function | nuclease activity | 257 / 301 | 85.4% | 98.9% of 260 | ≥80% support |
| GO | GO:0003906 Molecular Function | DNA-(apurinic or apyrimidinic site) endonuclease activity | 253 / 301 | 84.1% | 97.3% of 260 | ≥80% support |
| GO | GO:0006284 Biological Process | base-excision repair | 253 / 301 | 84.1% | 97.3% of 260 | ≥80% support |
| GO | GO:0008081 Molecular Function | phosphoric diester hydrolase activity | 253 / 301 | 84.1% | 97.3% of 260 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 251 / 301 | 83.4% | 96.5% of 260 | ≥80% support |
| GO | GO:0004519 Molecular Function | endonuclease activity | 251 / 301 | 83.4% | 96.5% of 260 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 246 / 301 | 81.7% | 94.6% of 260 | ≥80% support |
| KEGG | K10771 | APEX1 — DNA repair and recombination proteins | 182 / 301 | 60.5% | 93.3% of 195 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| No member of this family matches the current filter. | |||||
