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This orthogroup contains 75 genes from 38 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 75 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11539 | VDJ RECOMBINATION ACTIVATING PROTEIN 1 RAG1 | 52 / 75 | 69.3% | 94.6% of 55 | ≥50% support |
| Pfam | PF12940 | RAG1 | 46 / 75 | 61.3% | 86.8% of 53 | ≥50% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 53 / 75 | 70.7% | 98.2% of 54 | ≥50% support |
| GO | GO:0002250 Biological Process | adaptive immune response | 52 / 75 | 69.3% | 96.3% of 54 | ≥50% support |
| GO | GO:0002331 Biological Process | pre-B cell allelic exclusion | 52 / 75 | 69.3% | 96.3% of 54 | ≥50% support |
| GO | GO:0004519 Molecular Function | endonuclease activity | 52 / 75 | 69.3% | 96.3% of 54 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 52 / 75 | 69.3% | 96.3% of 54 | ≥50% support |
| GO | GO:0033151 Biological Process | V(D)J recombination | 52 / 75 | 69.3% | 96.3% of 54 | ≥50% support |
| GO | GO:0043565 Molecular Function | sequence-specific DNA binding | 52 / 75 | 69.3% | 96.3% of 54 | ≥50% support |
| GO | GO:0097519 Cellular Component | DNA recombinase complex | 52 / 75 | 69.3% | 96.3% of 54 | ≥50% support |
| GO | GO:1905347 Cellular Component | endodeoxyribonuclease complex | 52 / 75 | 69.3% | 96.3% of 54 | ≥50% support |
| GO | GO:1990238 Molecular Function | double-stranded DNA endonuclease activity | 52 / 75 | 69.3% | 96.3% of 54 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| No member of this family matches the current filter. | |||||
