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This orthogroup contains 5,156 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 5,156 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR18945 | NEUROTRANSMITTER GATED ION CHANNEL | 4668 / 5,156 | 90.5% | 99.9% of 4,674 | ≥80% support |
| Pfam | PF02931 | Neur_chan_LBD — Neurotransmitter-gated ion-channel ligand binding domain | 4502 / 5,156 | 87.3% | 95.2% of 4,727 | ≥80% support |
| Pfam | PF02932 | Neur_chan_memb — Neurotransmitter-gated ion-channel transmembrane region | 4371 / 5,156 | 84.8% | 92.5% of 4,727 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 4779 / 5,156 | 92.7% | 100.0% of 4,779 | ≥80% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 4779 / 5,156 | 92.7% | 100.0% of 4,779 | ≥80% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 4713 / 5,156 | 91.4% | 98.6% of 4,779 | ≥80% support |
| GO | GO:0034220 Biological Process | monoatomic ion transmembrane transport | 4712 / 5,156 | 91.4% | 98.6% of 4,779 | ≥80% support |
| GO | GO:0004888 Molecular Function | transmembrane signaling receptor activity | 4712 / 5,156 | 91.4% | 98.6% of 4,779 | ≥80% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 4669 / 5,156 | 90.6% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0007268 Biological Process | chemical synaptic transmission | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0030594 Molecular Function | neurotransmitter receptor activity | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0042391 Biological Process | regulation of membrane potential | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0043005 Cellular Component | neuron projection | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0045202 Cellular Component | synapse | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0050877 Biological Process | nervous system process | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0005230 Molecular Function | extracellular ligand-gated monoatomic ion channel activity | 4537 / 5,156 | 88.0% | 94.9% of 4,779 | ≥80% support |
| GO | GO:0005254 Molecular Function | chloride channel activity | 3382 / 5,156 | 65.6% | 70.8% of 4,779 | ≥50% support |
| GO | GO:1902476 Biological Process | chloride transmembrane transport | 3382 / 5,156 | 65.6% | 70.8% of 4,779 | ≥50% support |
| GO | GO:1904315 Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | 3377 / 5,156 | 65.5% | 70.7% of 4,779 | ≥50% support |
| GO | GO:0005231 Molecular Function | excitatory extracellular ligand-gated monoatomic ion channel activity | 3377 / 5,156 | 65.5% | 70.7% of 4,779 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora palmata | XP_074610428.1 | XP_029196997.1 | glycine receptor subunit alphaZ1-like isoform X2 [Acropora millepora] | P24046 Gamma-aminobutyric acid receptor subunit rho-1 OS=Homo sapie | JBrowse |
| Acropora palmata | XP_074610438.1 | XP_029196997.1 | glycine receptor subunit alphaZ1-like isoform X2 [Acropora millepora] | P24046 Gamma-aminobutyric acid receptor subunit rho-1 OS=Homo sapie | JBrowse |
| Acropora palmata | XP_074610448.1 | XP_029196997.1 | glycine receptor subunit alphaZ1-like isoform X2 [Acropora millepora] | P24046 Gamma-aminobutyric acid receptor subunit rho-1 OS=Homo sapie | JBrowse |
| Acropora palmata | XP_074610458.1 | XP_029196997.1 | glycine receptor subunit alphaZ1-like isoform X2 [Acropora millepora] | P24046 Gamma-aminobutyric acid receptor subunit rho-1 OS=Homo sapie | JBrowse |
| Acropora palmata | XP_074610467.1 | XP_029196997.1 | glycine receptor subunit alphaZ1-like isoform X2 [Acropora millepora] | P24046 Gamma-aminobutyric acid receptor subunit rho-1 OS=Homo sapie | JBrowse |
| Acropora palmata | XP_074610475.1 | XP_015773503.1 | PREDICTED: glycine receptor subunit alphaZ1-like isoform X1 [Acropora digitifera] | P24045 Gamma-aminobutyric acid receptor subunit beta-4 OS=Gallus ga | JBrowse |
| Acropora palmata | XP_074612126.1 | XP_029189093.2 | gamma-aminobutyric acid receptor subunit beta-like [Acropora millepora] | P26714 Gamma-aminobutyric acid receptor subunit beta OS=Lymnaea sta | JBrowse |
| Acropora palmata | XP_074614030.1 | XP_015774143.1 | PREDICTED: gamma-aminobutyric acid receptor subunit beta-like [Acropora digitifera] | P26714 Gamma-aminobutyric acid receptor subunit beta OS=Lymnaea sta | JBrowse |
| Acropora palmata | XP_074614031.1 | XP_015774143.1 | PREDICTED: gamma-aminobutyric acid receptor subunit beta-like [Acropora digitifera] | P26714 Gamma-aminobutyric acid receptor subunit beta OS=Lymnaea sta | JBrowse |
| Acropora palmata | XP_074614032.1 | XP_044172452.1 | uncharacterized protein LOC114958415 [Acropora millepora] | O75311 Glycine receptor subunit alpha-3 OS=Homo sapiens OX=9606 GN= | JBrowse |
| Acropora palmata | XP_074614033.1 | XP_044173351.1 | glycine receptor subunit alpha-2-like isoform X1 [Acropora millepora] | Q7TNC8 Glycine receptor subunit alpha-2 OS=Mus musculus OX=10090 GN | JBrowse |
| Acropora palmata | XP_074614034.1 | XP_044173354.1 | glycine receptor subunit alpha-2-like isoform X3 [Acropora millepora] | Q7TNC8 Glycine receptor subunit alpha-2 OS=Mus musculus OX=10090 GN | JBrowse |
| Acropora palmata | XP_074614035.1 | XP_044173351.1 | glycine receptor subunit alpha-2-like isoform X1 [Acropora millepora] | P18505 Gamma-aminobutyric acid receptor subunit beta-1 OS=Homo sapi | JBrowse |
| Acropora palmata | XP_074614036.1 | XP_029192012.2 | gamma-aminobutyric acid receptor subunit beta-like [Acropora millepora] | Q61603 Glycine receptor subunit alpha-4 OS=Mus musculus OX=10090 GN | JBrowse |
| Acropora palmata | XP_074614037.1 | XP_029192012.2 | gamma-aminobutyric acid receptor subunit beta-like [Acropora millepora] | Q61603 Glycine receptor subunit alpha-4 OS=Mus musculus OX=10090 GN | JBrowse |
| Acropora palmata | XP_074614038.1 | XP_029192012.2 | gamma-aminobutyric acid receptor subunit beta-like [Acropora millepora] | Q61603 Glycine receptor subunit alpha-4 OS=Mus musculus OX=10090 GN | JBrowse |
| Acropora palmata | XP_074614039.1 | XP_029192012.2 | gamma-aminobutyric acid receptor subunit beta-like [Acropora millepora] | Q61603 Glycine receptor subunit alpha-4 OS=Mus musculus OX=10090 GN | JBrowse |
| Acropora palmata | XP_074615000.1 | XP_029212016.1 | gamma-aminobutyric acid receptor subunit beta-1-like isoform X1 [Acropora millepora] | Q9GJS9 Glycine receptor subunit beta OS=Bos taurus OX=9913 GN=GLRB | JBrowse |
| Acropora palmata | XP_074615001.1 | XP_029212017.1 | glycine receptor subunit beta-like isoform X2 [Acropora millepora] | Q9GJS9 Glycine receptor subunit beta OS=Bos taurus OX=9913 GN=GLRB | JBrowse |
| Acropora palmata | XP_074615002.1 | XP_029212017.1 | glycine receptor subunit beta-like isoform X2 [Acropora millepora] | P56475 Gamma-aminobutyric acid receptor subunit rho-1 OS=Mus muscul | JBrowse |
