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This orthogroup contains 576 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 576 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11793 | BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR | 483 / 576 | 83.9% | 100.0% of 483 | ≥80% support |
| GO | GO:0000790 Cellular Component | chromatin | 483 / 576 | 83.9% | 100.0% of 483 | ≥80% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 483 / 576 | 83.9% | 100.0% of 483 | ≥80% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 483 / 576 | 83.9% | 100.0% of 483 | ≥80% support |
| GO | GO:0005667 Cellular Component | transcription regulator complex | 483 / 576 | 83.9% | 100.0% of 483 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 483 / 576 | 83.9% | 100.0% of 483 | ≥80% support |
| GO | GO:0046983 Molecular Function | protein dimerization activity | 468 / 576 | 81.3% | 96.9% of 483 | ≥80% support |
| Pfam | PF00010 | HLH — Helix-loop-helix DNA-binding domain | 460 / 576 | 79.9% | 100.0% of 460 | ≥50% support |
| KEGG | K15603 | TCF4_12 — Transcription factors | 335 / 576 | 58.2% | 100.0% of 335 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora palmata | XP_074614140.1 | XP_029197864.2 | transcription factor 12-like isoform X1 [Acropora millepora] | Q99081 Transcription factor 12 OS=Homo sapiens OX=9606 GN=TCF12 PE= | JBrowse |
| Acropora palmata | XP_074614141.1 | XP_029197865.2 | transcription factor 12-like isoform X2 [Acropora millepora] | Q99081 Transcription factor 12 OS=Homo sapiens OX=9606 GN=TCF12 PE= | JBrowse |
| Acropora palmata | XP_074614142.1 | XP_029197866.2 | transcription factor 12-like isoform X3 [Acropora millepora] | Q99081 Transcription factor 12 OS=Homo sapiens OX=9606 GN=TCF12 PE= | JBrowse |
| Acropora palmata | XP_074614143.1 | XP_029197868.2 | transcription factor 12-like isoform X5 [Acropora millepora] | Q99081 Transcription factor 12 OS=Homo sapiens OX=9606 GN=TCF12 PE= | JBrowse |
| Acropora palmata | XP_074614144.1 | XP_029197870.2 | transcription factor 12-like isoform X7 [Acropora millepora] | Q99081 Transcription factor 12 OS=Homo sapiens OX=9606 GN=TCF12 PE= | JBrowse |
| Acropora palmata | XP_074614145.1 | XP_029197874.2 | transcription factor 12-like isoform X11 [Acropora millepora] | Q62655 Transcription factor 4 OS=Rattus norvegicus OX=10116 GN=Tcf4 | JBrowse |
