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This orthogroup contains 206 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 206 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13325 | PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE | 185 / 206 | 89.8% | 100.0% of 185 | ≥80% support |
| Pfam | PF02163 | Peptidase_M50 — Peptidase family M50 | 171 / 206 | 83.0% | 100.0% of 171 | ≥80% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 185 / 206 | 89.8% | 100.0% of 185 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 185 / 206 | 89.8% | 100.0% of 185 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 185 / 206 | 89.8% | 100.0% of 185 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 185 / 206 | 89.8% | 100.0% of 185 | ≥80% support |
| GO | GO:0031293 Biological Process | membrane protein intracellular domain proteolysis | 185 / 206 | 89.8% | 100.0% of 185 | ≥80% support |
| GO | GO:0051091 Biological Process | positive regulation of DNA-binding transcription factor activity | 185 / 206 | 89.8% | 100.0% of 185 | ≥80% support |
| GO | GO:1905897 Biological Process | regulation of response to endoplasmic reticulum stress | 185 / 206 | 89.8% | 100.0% of 185 | ≥80% support |
| GO | GO:1990440 Biological Process | obsolete positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 185 / 206 | 89.8% | 100.0% of 185 | ≥80% support |
| KEGG | K07765 | MBTPS2 — Peptidases and inhibitors | 138 / 206 | 67.0% | 99.3% of 139 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora palmata | XP_074627303.1 | XP_029214053.2 | membrane-bound transcription factor site-2 protease-like [Acropora millepora] | Q8CHX6 Membrane-bound transcription factor site-2 protease OS=Mus m | JBrowse |
