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This orthogroup contains 1,089 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,089 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11447 | CELLULAR TUMOR ANTIGEN P53 | 981 / 1,089 | 90.1% | 99.8% of 983 | ≥80% support |
| Pfam | PF00870 | P53 | 974 / 1,089 | 89.4% | 98.7% of 987 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 984 / 1,089 | 90.4% | 99.4% of 990 | ≥80% support |
| GO | GO:0003700 Molecular Function | DNA-binding transcription factor activity | 984 / 1,089 | 90.4% | 99.4% of 990 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 984 / 1,089 | 90.4% | 99.4% of 990 | ≥80% support |
| GO | GO:0006355 Biological Process | regulation of DNA-templated transcription | 984 / 1,089 | 90.4% | 99.4% of 990 | ≥80% support |
| GO | GO:0006915 Biological Process | apoptotic process | 982 / 1,089 | 90.2% | 99.2% of 990 | ≥80% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 981 / 1,089 | 90.1% | 99.1% of 990 | ≥80% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 981 / 1,089 | 90.1% | 99.1% of 990 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 981 / 1,089 | 90.1% | 99.1% of 990 | ≥80% support |
| GO | GO:0000976 Molecular Function | transcription cis-regulatory region binding | 974 / 1,089 | 89.4% | 98.4% of 990 | ≥80% support |
| KEGG | K10149 | TP63 — Transcription factors | 625 / 1,089 | 57.4% | 98.0% of 638 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Astrangia poculata | evm.model.Ap14.1683 | XP_020604946.1 | cellular tumor antigen p53-like isoform X2 [Orbicella faveolata] | Q9XSK8 Tumor protein p73 OS=Chlorocebus aethiops OX=9534 GN=TP73 PE | JBrowse |
| Astrangia poculata | evm.model.Ap6.234 | XP_020628162.1 | cellular tumor antigen p53-like isoform X2 [Orbicella faveolata] | Q9JJP2 Tumor protein p73 OS=Mus musculus OX=10090 GN=Tp73 PE=1 SV=1 | JBrowse |
| Astrangia poculata | evm.model.Ap6.377 | KAJ7393325.1 | hypothetical protein OS493_006295 [Desmophyllum pertusum] | Q9H3D4 Tumor protein 63 OS=Homo sapiens OX=9606 GN=TP63 PE=1 SV=1 | JBrowse |
| Astrangia poculata | evm.model.Ap6.377.1.5f15dcc1 | XP_020606342.1 | cellular tumor antigen p53-like [Orbicella faveolata] | Q9XSK8 Tumor protein p73 OS=Chlorocebus aethiops OX=9534 GN=TP73 PE | JBrowse |
