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This orthogroup contains 1,022 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,022 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24340 | HOMEOBOX PROTEIN NKX | 921 / 1,022 | 90.1% | 99.9% of 922 | ≥80% support |
| Pfam | PF00046 | Homeodomain | 922 / 1,022 | 90.2% | 100.0% of 922 | ≥80% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 922 / 1,022 | 90.2% | 100.0% of 922 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 922 / 1,022 | 90.2% | 100.0% of 922 | ≥80% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 921 / 1,022 | 90.1% | 99.9% of 922 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 921 / 1,022 | 90.1% | 99.9% of 922 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 921 / 1,022 | 90.1% | 99.9% of 922 | ≥80% support |
| GO | GO:0030154 Biological Process | cell differentiation | 921 / 1,022 | 90.1% | 99.9% of 922 | ≥80% support |
| GO | GO:0006355 Biological Process | regulation of DNA-templated transcription | 786 / 1,022 | 76.9% | 85.3% of 922 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Astrangia poculata | evm.model.Ap11.1613 | KAJ7373206.1 | negative regulation of epithelial cell proliferation [Desmophyllum pertusum] | P42587 Homeobox protein XENK-2 OS=Xenopus laevis OX=8355 PE=2 SV=1 | JBrowse |
| Astrangia poculata | evm.model.Ap11.1614 | KAJ7373205.1 | DNA binding [Desmophyllum pertusum] | P97273 Thyroid transcription factor 1 (Fragment) OS=Cavia porcellus | JBrowse |
| Astrangia poculata | evm.model.Ap11.1615 | XP_020626113.1 | homeobox protein Nkx-2.8-like isoform X2 [Orbicella faveolata] | P42587 Homeobox protein XENK-2 OS=Xenopus laevis OX=8355 PE=2 SV=1 | JBrowse |
| Astrangia poculata | evm.model.Ap11.1615.1.5f15de5a | XP_020626112.1 | homeobox protein Nkx-2.8-like isoform X1 [Orbicella faveolata] | P42587 Homeobox protein XENK-2 OS=Xenopus laevis OX=8355 PE=2 SV=1 | JBrowse |
| Astrangia poculata | evm.model.Ap11.1616 | XP_020626111.1 | homeobox protein Nkx-2.2-like [Orbicella faveolata] | P42586 Homeobox protein Nkx-2.2 OS=Mus musculus OX=10090 GN=Nkx2-2 | JBrowse |
| Astrangia poculata | evm.model.Ap11.1617 | KAJ7373202.1 | hypothetical protein OS493_014350 [Desmophyllum pertusum] | Q90481 Homeobox protein Nkx-2.2a OS=Danio rerio OX=7955 GN=nkx2.2a | JBrowse |
| Astrangia poculata | evm.model.Ap2.1394 | KAJ7336657.1 | atrioventricular node cell fate commitment [Desmophyllum pertusum] | Q90788 Homeobox protein Nkx-2.5 OS=Gallus gallus OX=9031 GN=NKX-2.5 | JBrowse |
