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This orthogroup contains 395 genes from 146 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 395 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46006 | RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A | 205 / 395 | 51.9% | 60.8% of 337 | ≥50% support |
| Pfam | PF12763 | EF-hand_4 — Cytoskeletal-regulatory complex EF hand | 225 / 395 | 57.0% | 66.0% of 341 | ≥50% support |
| Pfam | PF14604 | SH3_9 — Variant SH3 domain | 223 / 395 | 56.5% | 65.4% of 341 | ≥50% support |
| Pfam | PF00621 | RhoGEF | 204 / 395 | 51.7% | 59.8% of 341 | ≥50% support |
| Pfam | PF16652 | PH_13 — Pleckstrin homology domain | 204 / 395 | 51.7% | 59.8% of 341 | ≥50% support |
| Pfam | PF00018 | SH3_1 — SH3 domain | 201 / 395 | 50.9% | 58.9% of 341 | ≥50% support |
| Pfam | PF00168 | C2 | 198 / 395 | 50.1% | 58.1% of 341 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 259 / 395 | 65.6% | 78.7% of 329 | ≥50% support |
| GO | GO:0005509 Molecular Function | calcium ion binding | 230 / 395 | 58.2% | 69.9% of 329 | ≥50% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 210 / 395 | 53.2% | 63.8% of 329 | ≥50% support |
| GO | GO:0035025 Biological Process | positive regulation of Rho protein signal transduction | 205 / 395 | 51.9% | 62.3% of 329 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Astrangia poculata | evm.model.Ap6.2740 | XP_020620178.1 | intersectin-1-like isoform X1 [Orbicella faveolata] | Q9WVE9 Intersectin-1 OS=Rattus norvegicus OX=10116 GN=Itsn1 PE=1 SV | JBrowse |
