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This orthogroup contains 308 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 308 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45888 | HL01030P-RELATED | 254 / 308 | 82.5% | 99.6% of 255 | ≥80% support |
| GO | GO:0003713 Molecular Function | transcription coactivator activity | 252 / 308 | 81.8% | 99.2% of 254 | ≥80% support |
| GO | GO:0042393 Molecular Function | histone binding | 252 / 308 | 81.8% | 99.2% of 254 | ≥80% support |
| GO | GO:0042800 Molecular Function | histone H3K4 methyltransferase activity | 252 / 308 | 81.8% | 99.2% of 254 | ≥80% support |
| GO | GO:0044666 Cellular Component | MLL3/4 complex | 252 / 308 | 81.8% | 99.2% of 254 | ≥80% support |
| GO | GO:0045944 Biological Process | positive regulation of transcription by RNA polymerase II | 252 / 308 | 81.8% | 99.2% of 254 | ≥80% support |
| Pfam | PF00628 | PHD | 206 / 308 | 66.9% | 81.8% of 252 | ≥50% support |
| Pfam | PF00856 | SET | 197 / 308 | 64.0% | 78.2% of 252 | ≥50% support |
| Pfam | PF05964 | FYRN — F/Y-rich N-terminus | 197 / 308 | 64.0% | 78.2% of 252 | ≥50% support |
| Pfam | PF05965 | FYRC — F/Y rich C-terminus | 195 / 308 | 63.3% | 77.4% of 252 | ≥50% support |
| Pfam | PF13771 | zf-HC5HC2H — PHD-like zinc-binding domain | 167 / 308 | 54.2% | 66.3% of 252 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 200 / 308 | 64.9% | 78.7% of 254 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 198 / 308 | 64.3% | 78.0% of 254 | ≥50% support |
| KEGG | K09188 | MLL3 — Chromosome and associated proteins | 183 / 308 | 59.4% | 97.3% of 188 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Astrangia poculata | evm.model.Ap7.1709 | XP_020624984.1 | histone-lysine N-methyltransferase 2D-like isoform X2 [Orbicella faveolata] | O14686 Histone-lysine N-methyltransferase 2D OS=Homo sapiens OX=960 | JBrowse |
