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This orthogroup contains 286 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 286 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR43016 | PRESEQUENCE PROTEASE | 247 / 286 | 86.4% | 100.0% of 247 | ≥80% support |
| GO | GO:0046872 Molecular Function | metal ion binding | 250 / 286 | 87.4% | 100.0% of 250 | ≥80% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 245 / 286 | 85.7% | 98.0% of 250 | ≥80% support |
| GO | GO:0016485 Biological Process | protein processing | 245 / 286 | 85.7% | 98.0% of 250 | ≥80% support |
| GO | GO:0005759 Cellular Component | mitochondrial matrix | 242 / 286 | 84.6% | 96.8% of 250 | ≥80% support |
| Pfam | PF08367 | M16C_assoc — Peptidase M16C associated | 214 / 286 | 74.8% | 89.2% of 240 | ≥50% support |
| Pfam | PF05193 | Peptidase_M16_C — Peptidase M16 inactive domain | 213 / 286 | 74.5% | 88.8% of 240 | ≥50% support |
| Pfam | PF00675 | Peptidase_M16 — Insulinase (Peptidase family M16) | 164 / 286 | 57.3% | 68.3% of 240 | ≥50% support |
| GO | GO:0006508 Biological Process | proteolysis | 217 / 286 | 75.9% | 86.8% of 250 | ≥50% support |
| KEGG | K06972 | PITRM1, PreP, CYM1 — Peptidases and inhibitors | 145 / 286 | 50.7% | 98.6% of 147 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Astrangia poculata | evm.model.Ap6.2473 | CAH3121497.1 | unnamed protein product [Pocillopora meandrina] | Q28BR5 Presequence protease, mitochondrial OS=Xenopus tropicalis OX | JBrowse |
| Astrangia poculata | evm.model.Ap6.2476 | XP_020626507.1 | presequence protease, mitochondrial-like [Orbicella faveolata] | Q28BR5 Presequence protease, mitochondrial OS=Xenopus tropicalis OX | JBrowse |
