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This orthogroup contains 268 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 268 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR43866 | MALONATE-SEMIALDEHYDE DEHYDROGENASE | 243 / 268 | 90.7% | 99.6% of 244 | ≥80% support |
| Pfam | PF00171 | Aldedh — Aldehyde dehydrogenase family | 244 / 268 | 91.0% | 100.0% of 244 | ≥80% support |
| GO | GO:0016491 Molecular Function | oxidoreductase activity | 244 / 268 | 91.0% | 100.0% of 244 | ≥80% support |
| GO | GO:0004491 Molecular Function | methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity | 243 / 268 | 90.7% | 99.6% of 244 | ≥80% support |
| GO | GO:0006210 Biological Process | thymine catabolic process | 243 / 268 | 90.7% | 99.6% of 244 | ≥80% support |
| GO | GO:0006574 Biological Process | valine catabolic process | 243 / 268 | 90.7% | 99.6% of 244 | ≥80% support |
| GO | GO:0018478 Molecular Function | malonate-semialdehyde dehydrogenase (acetylating) activity | 243 / 268 | 90.7% | 99.6% of 244 | ≥80% support |
| GO | GO:0016620 Molecular Function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | 227 / 268 | 84.7% | 93.0% of 244 | ≥80% support |
| KEGG | K00140 | mmsA, iolA, ALDH6A1 — beta-Alanine metabolism | 217 / 268 | 81.0% | 99.1% of 219 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 199 / 268 | 74.3% | 81.6% of 244 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Astrangia poculata | evm.model.Ap11.1517 | XP_020610339.1 | methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial-like [Orbicella faveolata] | Q02253 Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogen | JBrowse |
