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This orthogroup contains 266 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 266 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0005515 Molecular Function | protein binding | 218 / 266 | 82.0% | 94.8% of 230 | ≥80% support |
| PANTHER | PTHR22834 | NUCLEAR FUSION PROTEIN FUS2 | 209 / 266 | 78.6% | 91.3% of 229 | ≥50% support |
| Pfam | PF00621 | RhoGEF | 193 / 266 | 72.6% | 84.3% of 229 | ≥50% support |
| Pfam | PF03114 | BAR | 181 / 266 | 68.1% | 79.0% of 229 | ≥50% support |
| Pfam | PF14604 | SH3_9 — Variant SH3 domain | 179 / 266 | 67.3% | 78.2% of 229 | ≥50% support |
| Pfam | PF00018 | SH3_1 — SH3 domain | 162 / 266 | 60.9% | 70.7% of 229 | ≥50% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 212 / 266 | 79.7% | 92.2% of 230 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 210 / 266 | 79.0% | 91.3% of 230 | ≥50% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 166 / 266 | 62.4% | 72.2% of 230 | ≥50% support |
| KEGG | K20705 | DNMBP, ARHGEF36, TUBA — Membrane trafficking | 136 / 266 | 51.1% | 94.4% of 144 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Astrangia poculata | evm.model.Ap4.383 | XP_020612632.1 | uncharacterized protein LOC110050998 [Orbicella faveolata] | E7F1U2 Dynamin-binding protein OS=Danio rerio OX=7955 GN=dnmbp PE=2 | JBrowse |