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This orthogroup contains 262 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 262 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0003677 Molecular Function | DNA binding | 224 / 262 | 85.5% | 99.6% of 225 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 224 / 262 | 85.5% | 99.6% of 225 | ≥80% support |
| GO | GO:0006260 Biological Process | DNA replication | 224 / 262 | 85.5% | 99.6% of 225 | ≥80% support |
| GO | GO:0006310 Biological Process | DNA recombination | 211 / 262 | 80.5% | 93.8% of 225 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 211 / 262 | 80.5% | 93.8% of 225 | ≥80% support |
| PANTHER | PTHR23273 | REPLICATION FACTOR A 1, RFA1 | 209 / 262 | 79.8% | 98.6% of 212 | ≥50% support |
| Pfam | PF08646 | Rep_fac-A_C — Replication factor-A C terminal domain | 196 / 262 | 74.8% | 84.1% of 233 | ≥50% support |
| Pfam | PF16900 | REPA_OB_2 — Replication protein A OB domain | 195 / 262 | 74.4% | 83.7% of 233 | ≥50% support |
| Pfam | PF04057 | Rep-A_N — Replication factor-A protein 1, N-terminal domain | 184 / 262 | 70.2% | 79.0% of 233 | ≥50% support |
| Pfam | PF01336 | tRNA_anti-codon — OB-fold nucleic acid binding domain | 173 / 262 | 66.0% | 74.3% of 233 | ≥50% support |
| GO | GO:0006289 Biological Process | nucleotide-excision repair | 209 / 262 | 79.8% | 92.9% of 225 | ≥50% support |
| GO | GO:0005662 Cellular Component | DNA replication factor A complex | 209 / 262 | 79.8% | 92.9% of 225 | ≥50% support |
| GO | GO:0007004 Biological Process | telomere maintenance via telomerase | 209 / 262 | 79.8% | 92.9% of 225 | ≥50% support |
| GO | GO:0043047 Molecular Function | single-stranded telomeric DNA binding | 209 / 262 | 79.8% | 92.9% of 225 | ≥50% support |
| GO | GO:0051321 Biological Process | meiotic cell cycle | 209 / 262 | 79.8% | 92.9% of 225 | ≥50% support |
| GO | GO:0003684 Molecular Function | damaged DNA binding | 209 / 262 | 79.8% | 92.9% of 225 | ≥50% support |
| GO | GO:0000724 Biological Process | double-strand break repair via homologous recombination | 209 / 262 | 79.8% | 92.9% of 225 | ≥50% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 173 / 262 | 66.0% | 76.9% of 225 | ≥50% support |
| KEGG | K07466 | RFA1, RPA1, rpa — DNA repair and recombination proteins | 162 / 262 | 61.8% | 97.6% of 166 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Astrangia poculata | evm.model.Ap3.5 | XP_020607756.1 | replication protein A 70 kDa DNA-binding subunit-like [Orbicella faveolata] | Q01588 Replication protein A 70 kDa DNA-binding subunit OS=Xenopus | JBrowse |
