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This orthogroup contains 255 genes from 126 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 255 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11748 | D-LACTATE DEHYDROGENASE | 220 / 255 | 86.3% | 94.8% of 232 | ≥80% support |
| Pfam | PF02913 | FAD-oxidase_C — FAD linked oxidases, C-terminal domain | 216 / 255 | 84.7% | 93.1% of 232 | ≥80% support |
| Pfam | PF01565 | FAD_binding_4 — FAD binding domain | 207 / 255 | 81.2% | 89.2% of 232 | ≥80% support |
| GO | GO:0050660 Molecular Function | flavin adenine dinucleotide binding | 233 / 255 | 91.4% | 100.0% of 233 | ≥80% support |
| GO | GO:0004458 Molecular Function | D-lactate dehydrogenase (cytochrome) activity | 219 / 255 | 85.9% | 94.0% of 233 | ≥80% support |
| GO | GO:0008720 Molecular Function | D-lactate dehydrogenase activity | 219 / 255 | 85.9% | 94.0% of 233 | ≥80% support |
| GO | GO:1903457 Biological Process | lactate catabolic process | 219 / 255 | 85.9% | 94.0% of 233 | ≥80% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 217 / 255 | 85.1% | 93.1% of 233 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 212 / 255 | 83.1% | 91.0% of 233 | ≥80% support |
| GO | GO:0071949 Molecular Function | FAD binding | 210 / 255 | 82.4% | 90.1% of 233 | ≥80% support |
| KEGG | K00102 | LDHD, dld — Pyruvate metabolism | 176 / 255 | 69.0% | 97.8% of 180 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Astrangia poculata | evm.model.Ap4.6805 | XP_020624327.1 | probable D-lactate dehydrogenase, mitochondrial isoform X1 [Orbicella faveolata] | F1QXM5 Probable D-lactate dehydrogenase, mitochondrial OS=Danio rer | JBrowse |
