Gene Family

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Member genes
1,378
Species
143
Sequences
1,378
Best annotation support
85.6%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 85.6% of the 1,378 members.

Support counts the member genes carrying the term. % of genes is that count over all 1,378 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR11412MACROGLOBULIN / COMPLEMENT1180 / 1,37885.6%99.8%
of 1,182
≥80% support
PfamPF07678TED_complement — A-macroglobulin TED domain776 / 1,37856.3%66.0%
of 1,175
≥50% support
PfamPF07703A2M_BRD — Alpha-2-macroglobulin bait region domain728 / 1,37852.8%62.0%
of 1,175
≥50% support
PfamPF00207A2M — Alpha-2-macroglobulin family707 / 1,37851.3%60.2%
of 1,175
≥50% support
GOGO:0004866
Molecular Function
endopeptidase inhibitor activity869 / 1,37863.1%83.4%
of 1,042
≥50% support
GOGO:0005615
Cellular Component
extracellular space776 / 1,37856.3%74.5%
of 1,042
≥50% support
GOGO:0005576
Cellular Component
extracellular region698 / 1,37850.7%67.0%
of 1,042
≥50% support
📊 Total members in OG0000509: 15 (filtered to ASP2 · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

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